Improving tuberculosis prevention and care through addressing the global diabetes epidemic: from evidence to policy and practice.

Diabetes triples the risk of tuberculosis and is also a risk factor for adverse tuberculosis treatment outcomes, including death. Prevalence of diabetes is increasing globally, but most rapidly in low-income and middle-income countries where tuberculosis is a grave public health problem. Growth in this double disease burden creates additional obstacles for tuberculosis care and prevention. We review how the evolution of evidence on the link between tuberculosis and diabetes has informed global policy on collaborative activities, and how practice is starting to change as a consequence. We conclude that coordinated planning and service delivery across communicable and non-communicable disease programmes is necessary, feasible, and creates synergies that will help to reduce the burden of both tuberculosis and diabetes.

[1]  A. Harries,et al.  Screening tuberculosis patients for diabetes in a tribal area in South India. , 2013, Public health action.

[2]  M. Uplekar,et al.  Tuberculosis and noncommunicable diseases: neglected links and missed opportunities , 2010, European Respiratory Journal.

[3]  K. Stronks,et al.  Non-communicable diseases , 2011 .

[4]  C. Dye,et al.  Targets for global tuberculosis control. , 2006, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[5]  B. Weigl,et al.  New screening technologies for type 2 diabetes mellitus appropriate for use in tuberculosis patients. , 2013, Public health action.

[6]  C. Dye,et al.  Drivers of tuberculosis epidemics: the role of risk factors and social determinants. , 2009, Social science & medicine.

[7]  Bachti Alisjahbana,et al.  Clinical management of concurrent diabetes and tuberculosis and the implications for patient services. , 2014, The Lancet Diabetes and Endocrinology.

[8]  S. Satyanarayana,et al.  Tuberculosis-diabetes mellitus bidirectional screening at a tertiary care centre, South India. , 2013, Public health action.

[9]  D. Cook,et al.  Isoniazid for preventing tuberculosis in non-HIV infected persons. , 1999, The Cochrane database of systematic reviews.

[10]  A. Harries,et al.  Characteristics of patients with diabetes screened for tuberculosis in a tertiary care hospital in South India. , 2013, Public health action.

[11]  K. Dooley,et al.  Tuberculosis and diabetes mellitus: convergence of two epidemics. , 2009, The Lancet. Infectious diseases.

[12]  A. Harries,et al.  The impact of diabetes on tuberculosis treatment outcomes: A systematic review , 2011, BMC medicine.

[13]  G. Leung,et al.  Diabetic control and risk of tuberculosis: a cohort study. , 2008, American journal of epidemiology.

[14]  K. Floyd,et al.  Beyond UHC: Monitoring Health and Social Protection Coverage in the Context of Tuberculosis Care and Prevention , 2014, PLoS medicine.

[15]  M. Murray,et al.  Diabetes Mellitus Increases the Risk of Active Tuberculosis: A Systematic Review of 13 Observational Studies , 2008, PLoS medicine.

[16]  Z. Memish,et al.  Tuberculosis 2013 : 3 Tuberculosis comorbidity with communicable and non-communicable diseases : integrating health services and control eff orts , 2013 .

[17]  Eric S. Ramos,et al.  The Innovative Socio-economic Interventions Against Tuberculosis (ISIAT) project: an operational assessment. , 2011, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[18]  M. Uplekar,et al.  Systematic screening for active tuberculosis: rationale, definitions and key considerations. , 2013, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[19]  M. Raviglione,et al.  Financial burden for tuberculosis patients in low- and middle-income countries: a systematic review , 2014, European Respiratory Journal.

[20]  A. Harries,et al.  Bi‐directional screening for tuberculosis and diabetes: a systematic review , 2010, Tropical medicine & international health : TM & IH.

[21]  A. Harries,et al.  Is screening for diabetes among tuberculosis patients feasible at the field level? , 2013, Public health action.

[22]  B. Alisjahbana,et al.  Implications of the global increase of diabetes for tuberculosis control and patient care , 2010, Tropical medicine & international health : TM & IH.

[23]  A. V. Lesnichiĭ,et al.  [Experience with the chemoprophylaxis of pulmonary tuberculosis in diabetes mellitus patients]. , 1969, Problemy tuberkuleza.

[24]  G. Roglić,et al.  Nutrition, Diabetes and Tuberculosis in the Epidemiological Transition , 2011, PloS one.

[25]  A. Harries,et al.  Screening of patients with tuberculosis for diabetes mellitus in China , 2012, Tropical medicine & international health : TM & IH.

[26]  A. Harries,et al.  The looming epidemic of diabetes-associated tuberculosis: learning lessons from HIV-associated tuberculosis. , 2011, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[27]  R. Erasmus,et al.  The significance of glucose intolerance in pulmonary tuberculosis. , 1990, Tubercle.

[28]  Richard G. White,et al.  The effect of diabetes and undernutrition trends on reaching 2035 global tuberculosis targets. , 2014, The lancet. Diabetes & endocrinology.

[29]  Philippe Glaziou,et al.  Tuberculosis control and elimination 2010–50: cure, care, and social development , 2010, The Lancet.

[30]  J. Hackman,et al.  Three months of rifapentine and isoniazid for latent tuberculosis infection. , 2011, The New England journal of medicine.

[31]  Bernadette A. Thomas,et al.  Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 , 2012, The Lancet.

[32]  M. Ezzati,et al.  National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants , 2011, The Lancet.

[33]  G. Roglić,et al.  Diabetes and the risk of tuberculosis: a neglected threat to public health? , 2007, Chronic illness.

[34]  M. Raviglione The Global Plan to Stop TB, 2006-2015. , 2006, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[35]  T. Cohen,et al.  Diabetes mellitus and tuberculosis in countries with high tuberculosis burdens: individual risks and social determinants. , 2011, International journal of epidemiology.

[36]  K. Floyd,et al.  Scaling up interventions to achieve global tuberculosis control: progress and new developments , 2012, The Lancet.

[37]  R. Pfaffenberg,et al.  [Isoniazid & recurrence of tuberculosis in diabetics]. , 1958, Zeitschrift fur Tuberkulose.

[38]  Lesnichiĭ Av,et al.  Experience with the chemoprophylaxis of pulmonary tuberculosis in diabetes mellitus patients , 1969 .

[39]  A. Harries,et al.  Epidemiology and interaction of diabetes mellitus and tuberculosis and challenges for care: a review. , 2013, Public health action.

[40]  K. Mathur,et al.  Manifest, chemical and latent chemical diabetes in pulmonary tuberculosis. , 1973, The Journal of the Association of Physicians of India.

[41]  Xiaolin Wei,et al.  Providing financial incentives to rural-to-urban tuberculosis migrants in Shanghai: an intervention study , 2012, Infectious Diseases of Poverty.

[42]  G. Roglić,et al.  Defining the research agenda to reduce the joint burden of disease from Diabetes mellitus and Tuberculosis , 2010, Tropical medicine & international health : TM & IH.

[43]  Z. Memish,et al.  Tuberculosis comorbidity with communicable and non-communicable diseases: integrating health services and control efforts. , 2013, The Lancet. Infectious diseases.

[44]  G. Bjune,et al.  A systematic review of delay in the diagnosis and treatment of tuberculosis , 2008, BMC public health.

[45]  P. Garner,et al.  Systematic review of randomised controlled trials of strategies to promote adherence to tuberculosis treatment , 1997, BMJ.

[46]  Screening of patients with diabetes mellitus for tuberculosis in India , 2013, Tropical medicine & international health : TM & IH.

[47]  A. Harries,et al.  Screening patients with tuberculosis for diabetes mellitus in Gujarat, India. , 2013, Public health action.

[48]  A. Motala,et al.  Global estimates of undiagnosed diabetes in adults. , 2014, Diabetes research and clinical practice.

[49]  Z. Gülbaş,et al.  Impaired glucose tolerance in pulmonary tuberculosis. , 1987, European journal of respiratory diseases.

[50]  J. Golub,et al.  The benefits to communities and individuals of screening for active tuberculosis disease: a systematic review. , 2013, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[51]  K. Dou,et al.  Prevalence of diabetes among men and women in China. , 2010, The New England journal of medicine.

[52]  A. Harries,et al.  Screening patients with Diabetes Mellitus for Tuberculosis in China , 2012, Tropical medicine & international health : TM & IH.

[53]  A. Harries,et al.  Consultation meeting on tuberculosis and diabetes mellitus: meeting summary and recommendations. , 2010, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[54]  S. Nair,et al.  High prevalence of undiagnosed diabetes among tuberculosis patients in peripheral health facilities in Kerala. , 2013, Public health action.

[55]  K. Floyd,et al.  MDR tuberculosis--critical steps for prevention and control. , 2010, The New England journal of medicine.