Isolation of Prenylated Flavone from the Bark of Artocarpus Elasticus Alor Island – East Nusa Tenggara

Artonin E, is a prenylated flavoned in the form of a yellow solid with a melting point 143-145 C,. It has been isolated from the bark of Artocarpus Elasticus, which is an endemic plant from Alor Island – East Nusa Tenggara with local name Tongtong that has potential as a flavonoids source. The separation process resulted from the ethyl acetate extraction was fractionated by vacuum liquid chromatography with methylene chloride, ethyl acetate, and methanol based on increasing polarity. Purification was done by recrystallization using a solvent mixture of heated methylene chloride and n-hexane. The structure of compound was determined by UV, IR and NMR spectroscopy.