Recent Developments in Artificial Molecular-Machine–Based Active Nanomaterials and Nanosystems

Artificial molecular machines capable of converting chemical, electrochemical, and photochemical energy into mechanical motion represent a high-impact, fast-growing field of interdisciplinary research. These molecular-scale systems utilize a "bottom-up" technology centered upon the design and manipulation of molecular assemblies and are potentially capable of delivering efficient actuation at length scales dramatically smaller than traditional microscale actuators. As actuation materials, molecular machines have many advantages, such as high strain (40%-60%), high force and energy densities, and the capability to maintain their actuation properties from the level of a single molecule to the macroscale. These advantages have inspired researchers to develop molecular-machine-based active nanomaterials and nanosystems, including electroactive and photoactive polymers. This article will discuss the structures and properties of artificial molecular machines, as well as review recent progress on efforts to move molecular machines from solution to surfaces to devices.

[1]  Francesco Zerbetto,et al.  Macroscopic transport by synthetic molecular machines , 2005, Nature materials.

[2]  Hsian-Rong Tseng,et al.  Molecular-mechanical switch-based solid-state electrochromic devices. , 2004, Angewandte Chemie.

[3]  Stoddart,et al.  Artificial Molecular Machines. , 2000, Angewandte Chemie.

[4]  Francesco Zerbetto,et al.  Patterning through controlled submolecular motion: rotaxane-based switches and logic gates that function in solution and polymer films. , 2005, Angewandte Chemie.

[5]  Chih-Ming Ho,et al.  Linear artificial molecular muscles. , 2005, Journal of the American Chemical Society.

[6]  J. F. Stoddart,et al.  A chemically and electrochemically switchable molecular shuttle , 1994, Nature.

[7]  A. Ulman.  Characterization of Organic Thin Films , 1994 .

[8]  Kazuhiko Kinosita,et al.  Direct observation of the rotation of F1-ATPase , 1997, Nature.

[9]  R. Vale,et al.  The way things move: looking under the hood of molecular motor proteins. , 2000, Science.

[10]  Stoddart,et al.  Electronically configurable molecular-based logic gates , 1999, Science.

[11]  Xiang Zhang,et al.  The metastability of an electrochemically controlled nanoscale machine on gold surfaces. , 2004, Chemphyschem : a European journal of chemical physics and physical chemistry.

[12]  Richard A. Silva,et al.  Unidirectional rotary motion in a molecular system , 1999, Nature.

[13]  D. Hackney,et al.  The kinetic cycles of myosin, kinesin, and dynein. , 1996, Annual review of physiology.

[14]  F. Paolucci,et al.  Photoinduction of Fast, Reversible Translational Motion in a Hydrogen-Bonded Molecular Shuttle , 2001, Science.

[15]  T. Aida,et al.  Toward intelligent molecular machines: directed motions of biological and artificial molecules and assemblies. , 2005, Chemical reviews.

[16]  Masahiro Higuchi,et al.  Current/Voltage Characteristics of Monolayers of Redox‐Switchable [2]Catenanes on Gold , 2000 .

[17]  J Fraser Stoddart,et al.  An acid-base switchable [2]rotaxane. , 2002, The Journal of organic chemistry.

[18]  Chih-Ming Ho,et al.  Mechanical Shuttling of Linear Motor-Molecules in Condensed Phases on Solid Substrates , 2004 .

[19]  Michael C. Petty,et al.  Langmuir-Blodgett films: Interaction of electromagnetic radiation with organic thin films , 1996 .

[20]  Tohru Yamamoto,et al.  Langmuir and Langmuir-Blodgett films of amphiphilic bistable rotaxanes. , 2004, Langmuir : the ACS journal of surfaces and colloids.

[21]  Laurence Raehm,et al.  A Transition Metal Containing Rotaxane in Motion: Electrochemically Induced Pirouetting of the Ring on the Threaded Dumbbell , 1999 .

[22]  Chih-Ming Ho,et al.  A nanomechanical device based on linear molecular motors , 2004 .

[23]  Yi Liu,et al.  Understanding and harnessing biomimetic molecular machines for NEMS actuation materials , 2006, IEEE Transactions on Automation Science and Engineering.

[24]  Vincenzo Balzani,et al.  Molecular Devices and Machines– A Journey into the Nano World , 2003 .

[25]  H. Craighead,et al.  Powering an inorganic nanodevice with a biomolecular motor. , 2000, Science.

[26]  A new structural state of myosin. , 2004, Trends in biochemical sciences.

[27]  J. Howard,et al.  Molecular motors: structural adaptations to cellular functions , 1997, Nature.

[28]  Ronald D. Vale,et al.  Crystal structure of the kinesin motor domain reveals a structural similarity to myosin , 1996, Nature.

[29]  Nathalie Katsonis,et al.  Molecular machines: Nanomotor rotates microscale objects , 2006, Nature.

[30]  Yoseph Bar-Cohen,et al.  Electroactive Polymer (EAP) Actuators as Artificial Muscles: Reality, Potential, and Challenges, Second Edition , 2004 .