Molecular engineering of a backwards-moving myosin motor

[1]  G. Schulz,et al.  Self-Assembly of Proteins into Designed Networks , 2003, Science.

[2]  A. Becker,et al.  A structural model for actin-induced nucleotide release in myosin , 2003, Nature Structural Biology.

[3]  D. Manstein,et al.  Mutations in the relay loop region result in dominant‐negative inhibition of myosin II function in Dictyostelium , 2002, EMBO reports.

[4]  M. Kollmar,et al.  Crystal structure of the motor domain of a class‐I myosin , 2002, The EMBO journal.

[5]  D. Soldati,et al.  Toxoplasma gondii myosin A and its light chain: a fast, single‐headed, plus‐end‐directed motor , 2002, The EMBO journal.

[6]  T. Ikemura,et al.  Creation and characterization of temperature-sensitive CENP-C mutants in vertebrate cells. , 2001, Nucleic acids research.

[7]  Mitsuo Ikebe,et al.  The core of the motor domain determines the direction of myosin movement , 2001, Nature.

[8]  A. Nakai,et al.  Cell cycle transition under stress conditions controlled by vertebrate heat shock factors , 2001, The EMBO journal.

[9]  J. Berg,et al.  A millennial myosin census. , 2001, Molecular biology of the cell.

[10]  Dietmar J. Manstein,et al.  Single-molecule tracking of myosins with genetically engineered amplifier domains , 2001, Nature Structural Biology.

[11]  M. Kollmar,et al.  Structure of a genetically engineered molecular motor , 2001, The EMBO journal.

[12]  Alfred Wittinghofer,et al.  Triphosphate structure of guanylate‐binding protein 1 and implications for nucleotide binding and GTPase mechanism , 2000, The EMBO journal.

[13]  B. Graveley.  Sorting out the complexity of SR protein functions. , 2000, RNA.

[14]  B. Remmel,et al.  Stabilization of the actomyosin complex by negative charges on myosin. , 2000, Biochemistry.

[15]  T. James,et al.  Dynamic changes in small nuclear ribonucleoproteins of heat-stressed and thermotolerant HeLa cells. , 2000, The international journal of biochemistry & cell biology.

[16]  R. Vale,et al.  The way things move: looking under the hood of molecular motor proteins. , 2000, Science.

[17]  D. Manstein,et al.  Charge changes in loop 2 affect the thermal unfolding of the myosin motor domain bound to F-actin. , 2000, Biochemistry.

[18]  Daniel Safer,et al.  Myosin VI is an actin-based motor that moves backwards , 1999, Nature.

[19]  D. Manstein,et al.  Disturbed Communication between Actin- and Nucleotide-binding Sites in a Myosin II with Truncated 50/20-kDa Junction* , 1999, The Journal of Biological Chemistry.

[20]  Justin E. Molloy,et al.  The motor protein myosin-I produces its working stroke in two steps , 1999, Nature.

[21]  J. Tazi,et al.  Antagonism between RSF1 and SR proteins for both splice-site recognition in vitro and Drosophila development. , 1999, Genes & development.

[22]  O. Bensaude,et al.  Heat shock of HeLa cells inactivates a nuclear protein phosphatase specific for dephosphorylation of the C-terminal domain of RNA polymerase II. , 1999, Nucleic acids research.

[23]  D. Manstein,et al.  Differences in the ionic interaction of actin with the motor domains of nonmuscle and muscle myosin II. , 1999, European journal of biochemistry.

[24]  J. Manley,et al.  Phosphorylation–dephosphorylation differentially affects activities of splicing factor ASF/SF2 , 1998, The EMBO journal.

[25]  Roberto Dominguez,et al.  Crystal Structure of a Vertebrate Smooth Muscle Myosin Motor Domain and Its Complex with the Essential Light Chain Visualization of the Pre–Power Stroke State , 1998, Cell.

[26]  J. Manley,et al.  Genetic analysis of the SR protein ASF/SF2: interchangeability of RS domains and negative control of splicing. , 1998, Genes & development.

[27]  D. Manstein,et al.  Modulation of actin affinity and actomyosin adenosine triphosphatase by charge changes in the myosin motor domain. , 1998, Biochemistry.

[28]  J. Manley,et al.  Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing. , 1997, Genes & development.

[29]  M Anson,et al.  Myosin motors with artificial lever arms. , 1996, The EMBO journal.

[30]  J. Manley,et al.  Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability. , 1996, Genes & development.

[31]  J. Manley,et al.  SR proteins and splicing control. , 1996, Genes & development.

[32]  Renata Gattoni,et al.  The human hnRNP-M proteins: structure and relation with early heat shock-induced splicing arrest and chromosome mapping , 1996, Nucleic Acids Res..

[33]  J. Spudich,et al.  The neck region of the myosin motor domain acts as a lever arm to generate movement. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[34]  S. Lindquist,et al.  Heat-shock proteins Hsp104 and Hsp70 reactivate mRNA splicing after heat inactivation , 1995, Current Biology.

[35]  K. Holmes,et al.  An atomic model of the unregulated thin filament obtained by X-ray fiber diffraction on oriented actin-tropomyosin gels. , 1995, Journal of molecular biology.

[36]  M. Garcia-Blanco,et al.  Protein–protein interactions and 5'-splice-site recognition in mammalian mRNA precursors , 1994, Nature.

[37]  Ivan Rayment,et al.  Three-dimensional atomic model of F-actin decorated with Dictyostelium myosin S1 , 1993, Nature.

[38]  R A Milligan,et al.  Structure of the actin-myosin complex and its implications for muscle contraction. , 1993, Science.

[39]  K. Hall,et al.  The 5' splice site consensus RNA oligonucleotide induces assembly of U2/U4/U5/U6 small nuclear ribonucleoprotein complexes. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[40]  R. Lührmann,et al.  A splicing factor that is inactivated during in vivo heat shock is functionally equivalent to the [U4/U6.U5] triple snRNP-specific proteins. , 1992, Genes & development.

[41]  Z. Dominski,et al.  Inactivation of splicing factors in HeLa cells subjected to heat shock. , 1990, The Journal of biological chemistry.

[42]  J. Spudich,et al.  Expression and characterization of a functional myosin head fragment in Dictyostelium discoideum. , 1989, Science.

[43]  U. Bond,et al.  Heat shock but not other stress inducers leads to the disruption of a sub‐set of snRNPs and inhibition of in vitro splicing in HeLa cells. , 1988, The EMBO journal.

[44]  James A. Spudich,et al.  Myosin subfragment-1 is sufficient to move actin filaments in vitro , 1987, Nature.

[45]  J. Spudich,et al.  Fluorescent actin filaments move on myosin fixed to a glass surface. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[46]  S. Lindquist,et al.  RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis , 1986, Cell.

[47]  J. M. Velazquez,et al.  hsp70: Nuclear concentration during environmental stress and cytoplasmic storage during recovery , 1984, Cell.

[48]  S. Lehrer,et al.  Intrinsic fluorescence of actin. , 1972, Biochemistry.

[49]  A. Arrigo,et al.  Immunofluorescence localization of a small heat shock protein (hsp 23) in salivary gland cells of Drosophila melanogaster , 2004, Molecular and General Genetics MGG.

[50]  F. Kull,et al.  Kinesin: switch I & II and the motor mechanism. , 2002, Journal of cell science.

[51]  N. Guex,et al.  SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling , 1997, Electrophoresis.

[52]  S. Lindquist,et al.  RNA metabolism: strategies for regulation in the heat shock response. , 1990, Trends in genetics : TIG.