Antibiotics and antibiotic resistant genes (ARGs) in groundwater: A global review on dissemination, sources, interactions, environmental and human health risks.

[1]  Xianju Li,et al.  Antibiotic resistance gene profiling in response to antibiotic usage and environmental factors in the surface water and groundwater of Honghu Lake, China , 2020, Environmental Science and Pollution Research.

[2]  Siyan Zhao,et al.  Abundance of organohalide respiring bacteria and their role in dehalogenating antimicrobials in wastewater treatment plants. , 2020, Water research.

[3]  V. Sharma,et al.  Occurrence and toxicity of antibiotics in the aquatic environment: A review. , 2020, Chemosphere.

[4]  P. Alvarez,et al.  Antibiotic resistance genes from livestock waste: occurrence, dissemination, and treatment , 2020, npj Clean Water.

[5]  M. Zhang,et al.  Contamination profile of antibiotic resistance genes in ground water in comparison with surface water. , 2020, The Science of the total environment.

[6]  G. Ying,et al.  Swine farming elevated the proliferation of Acinetobacter with the prevalence of antibiotic resistance genes in the groundwater. , 2020, Environment international.

[7]  D. Sano,et al.  Understanding human health risks caused by antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARG) in water environments: Current knowledge and questions to be answered , 2020 .

[8]  Yingjie Dai,et al.  A review on pollution situation and treatment methods of tetracycline in groundwater , 2020, Separation Science and Technology.

[9]  J. O’Dwyer,et al.  Groundwater resources as a global reservoir for antimicrobial-resistant bacteria. , 2019, Water research.

[10]  H. Furumai,et al.  Concurrence of antibiotic resistant bacteria (ARB), viruses, pharmaceuticals and personal care products (PPCPs) in ambient waters of Guwahati, India: Urban vulnerability and resilience perspective. , 2019, The Science of the total environment.

[11]  K. Demeestere,et al.  Occurrence and treatment of contaminants of emerging concern in the African aquatic environment: Literature review and a look ahead. , 2019, Journal of environmental management.

[12]  Assessing the Influence of Environmental Factors on Groundwater Antibiotic Occurrence by Means of Variation Partitioning , 2019, Water.

[13]  M. C. L. Nogueira,et al.  Phenotypic and genotypic profile of the antimicrobial resistance of bacterial isolates and evaluation of physical and chemical potability indicators in groundwater in Brazil. , 2019, International journal of environmental health research.

[14]  P. Groundwater,et al.  Novel diagnostics for point-of-care bacterial detection and identification , 2019, RSC advances.

[15]  W. Gwenzi,et al.  Antibiotic resistance in drinking water systems: Occurrence, removal, and human health risks. , 2019, The Science of the total environment.

[16]  M. Díaz-Cruz,et al.  Occurrence, fate and environmental risk assessment of the organic microcontaminants included in the Watch Lists set by EU Decisions 2015/495 and 2018/840 in the groundwater of Spain. , 2019, The Science of the total environment.

[17]  H. Hollert,et al.  Optimization of screening-level risk assessment and priority selection of emerging pollutants - The case of pharmaceuticals in European surface waters. , 2019, Environment international.

[18]  C. Viboud,et al.  Population-level mathematical modeling of antimicrobial resistance: a systematic review , 2019, BMC Medicine.

[19]  L. Campos,et al.  Occurrence of PPCPs in a Brazilian water reservoir and their removal efficiency by ecological filtration. , 2019, Chemosphere.

[20]  Jiayin Ling,et al.  Dissemination of antibiotic resistance genes (ARGs) by rainfall on a cyclic economic breeding livestock farm , 2019, International Biodeterioration & Biodegradation.

[21]  Lei Wang,et al.  Occurrence and fate of antibiotics and antibiotic resistance genes in typical urban water of Beijing, China. , 2019, Environmental pollution.

[22]  J. Snape,et al.  Spatially Explicit Large-Scale Environmental Risk Assessment of Pharmaceuticals in Surface Water in China. , 2019, Environmental science & technology.

[23]  C. Oguh,et al.  Physicochemical Properties, Bacteriological Quality and Antimicrobial Resistance Profile of Isolates from Groundwater Sources in Ile-Ife Suburbs, Southwest Nigeria , 2019 .

[24]  M. Scheringer,et al.  Health and ecological risk assessment of emerging contaminants (pharmaceuticals, personal care products, and artificial sweeteners) in surface and groundwater (drinking water) in the Ganges River Basin, India. , 2019, The Science of the total environment.

[25]  S. Sanches,et al.  Anaerobic biodegradation of pharmaceutical compounds: New insights into the pharmaceutical-degrading bacteria. , 2018, Journal of hazardous materials.

[26]  Jun Huang,et al.  Typical pharmaceuticals in major WWTPs in Beijing, China: Occurrence, load pattern and calculation reliability. , 2018, Water research.

[27]  K. Rudi,et al.  Investigating antibiotics, antibiotic resistance genes, and microbial contaminants in groundwater in relation to the proximity of urban areas. , 2018, Environmental pollution.

[28]  S. Jin,et al.  Presence of Antibiotics in Shallow Groundwater in the Northern and Southwestern Regions of China , 2018, Ground water.

[29]  S. Castiglioni,et al.  Monitoring emerging contaminants in the drinking water of Milan and assessment of the human risk. , 2018, International journal of hygiene and environmental health.

[30]  H. Goossens,et al.  Global increase and geographic convergence in antibiotic consumption between 2000 and 2015 , 2018, Proceedings of the National Academy of Sciences.

[31]  N. Marathe,et al.  Antibiotics and common antibacterial biocides stimulate horizontal transfer of resistance at low concentrations. , 2018, The Science of the total environment.

[32]  W. Gwenzi,et al.  Sources, behaviour and health risks of antimicrobial resistance genes in wastewaters: A hotspot reservoir , 2018 .

[33]  T. Ren,et al.  Antibiotic residues in liquid manure from swine feedlot and their effects on nearby groundwater in regions of North China , 2018, Environmental Science and Pollution Research.

[34]  M. Petrovíc,et al.  Towards the understanding of antibiotic occurrence and transport in groundwater: Findings from the Baix Fluvià alluvial aquifer (NE Catalonia, Spain). , 2018, The Science of the total environment.

[35]  Yong-guan Zhu,et al.  Review of antibiotic resistance in China and its environment. , 2018, Environment international.

[36]  Qing‐Lin Chen,et al.  An underappreciated hotspot of antibiotic resistance: The groundwater near the municipal solid waste landfill. , 2017, The Science of the total environment.

[37]  O. Jolliet,et al.  Modeling the Emergence of Antibiotic Resistance in the Environment: an Analytical Solution for the Minimum Selection Concentration , 2017, Antimicrobial Agents and Chemotherapy.

[38]  Z. Iqbal,et al.  The global distribution and spread of the mobilized colistin resistance gene mcr-1 , 2018, Nature Communications.

[39]  Ki‐Hyun Kim,et al.  Occurrences and removal of pharmaceuticals and personal care products (PPCPs) in drinking water and water/sewage treatment plants: A review. , 2017, The Science of the total environment.

[40]  A. Alves,et al.  Characterization of antibiotic resistant and pathogenic Escherichia coli in irrigation water and vegetables in household farms. , 2017, International journal of food microbiology.

[41]  M. Borchardt,et al.  Review: Epidemiological evidence of groundwater contribution to global enteric disease, 1948–2015 , 2017, Hydrogeology Journal.

[42]  S. Harrad,et al.  Pharmaceuticals and personal care products (PPCPs) in the freshwater aquatic environment , 2017 .

[43]  Parul,et al.  Occurrence of multidrug resistant Escherichia coli in groundwater of Brij region (Uttar Pradesh) and its public health implications , 2017, Veterinary world.

[44]  M. Ashfaq,et al.  Ecological risk assessment of pharmaceuticals in the receiving environment of pharmaceutical wastewater in Pakistan. , 2017, Ecotoxicology and environmental safety.

[45]  Yan-xin Wang,et al.  Occurrence and risk assessment of antibiotics in surface water and groundwater from different depths of aquifers: A case study at Jianghan Plain, central China. , 2017, Ecotoxicology and environmental safety.

[46]  Charmaine Ng,et al.  Identification of antibiotic resistant bacteria community and a GeoChip based study of resistome in urban watersheds. , 2016, Water research.

[47]  A. Singer,et al.  Review of Antimicrobial Resistance in the Environment and Its Relevance to Environmental Regulators , 2016, Front. Microbiol..

[48]  Lúcia Santos,et al.  Antibiotics in the aquatic environments: A review of the European scenario. , 2016, Environment international.

[49]  Oluwawemimo Adebowale,et al.  Pratiques d’utilisation des antibiotiques dans les élevages de poules pondeuses dans l’Etat d’Ogun au Nigeria , 2016 .

[50]  Y. Taur,et al.  Antibiotic-Induced Changes in the Intestinal Microbiota and Disease. , 2016, Trends in molecular medicine.

[51]  Jim J. Ryan,et al.  Use of acute and chronic ecotoxicity data in environmental risk assessment of pharmaceuticals , 2016, Environmental toxicology and chemistry.

[52]  Gang Yu,et al.  Occurrence, sources and fate of pharmaceuticals and personal care products in the groundwater: A review , 2015 .

[53]  S. Frey,et al.  Quantitative Campylobacter spp., antibiotic resistance genes, and veterinary antibiotics in surface and ground water following manure application: Influence of tile drainage control. , 2015, The Science of the total environment.

[54]  John L. Zhou,et al.  Adsorptive removal of antibiotics from water and wastewater: Progress and challenges. , 2015, The Science of the total environment.

[55]  Yan-xin Wang,et al.  Seasonal variation of antibiotics concentration in the aquatic environment: a case study at Jianghan Plain, central China. , 2015, The Science of the total environment.

[56]  Dongqiang Zhu,et al.  Influence of Dissolved Organic Matter on Tetracycline Bioavailability to an Antibiotic-Resistant Bacterium. , 2015, Environmental science & technology.

[57]  Benjamin Lopez,et al.  Screening of French groundwater for regulated and emerging contaminants. , 2015, The Science of the total environment.

[58]  Miao Li,et al.  Occurrences and regional distributions of 20 antibiotics in water bodies during groundwater recharge. , 2015, The Science of the total environment.

[59]  A. Lin,et al.  Occurrence of pharmaceuticals, hormones, and perfluorinated compounds in groundwater in Taiwan , 2015, Environmental Monitoring and Assessment.

[60]  T. Schwartz,et al.  Microbiological characterization of aquatic microbiomes targeting taxonomical marker genes and antibiotic resistance genes of opportunistic bacteria. , 2015, The Science of the total environment.

[61]  C. L. Ventola The antibiotic resistance crisis: part 1: causes and threats. , 2015, P & T : a peer-reviewed journal for formulary management.

[62]  F. Baquero,et al.  Tackling antibiotic resistance: the environmental framework , 2015, Nature Reviews Microbiology.

[63]  D. Barceló,et al.  Occurrence of antibiotics and antibiotic resistance genes in hospital and urban wastewaters and their impact on the receiving river. , 2015, Water research.

[64]  B. Berglund Environmental dissemination of antibiotic resistance genes and correlation to anthropogenic contamination with antibiotics , 2015, Infection ecology & epidemiology.

[65]  Yan-xin Wang,et al.  Occurrence of antibiotics in the aquatic environment of Jianghan Plain, central China. , 2014, The Science of the total environment.

[66]  Xianzhi Peng,et al.  Occurrence and ecological potential of pharmaceuticals and personal care products in groundwater and reservoirs in the vicinity of municipal landfills in China. , 2014, The Science of the total environment.

[67]  A. Machado,et al.  Prevalence of antibiotic resistance in bacteria isolated from drinking well water available in Guinea-Bissau (West Africa). , 2014, Ecotoxicology and environmental safety.

[68]  A. Mittal,et al.  Risk assessment of antibiotic residues in different water matrices in India: key issues and challenges , 2014, Environmental Science and Pollution Research.

[69]  C. Ateba,et al.  Detection of vanA and vanB genes in vancomycin-resistant enterococci (VRE) from groundwater using multiplex PCR analysis. , 2013, Journal of water and health.

[70]  M. Wong,et al.  Pharmaceuticals and personal care products (PPCPs): a review on environmental contamination in China. , 2013, Environment international.

[71]  J. Fick,et al.  Occurrence and Abundance of Antibiotics and Resistance Genes in Rivers, Canal and near Drug Formulation Facilities – A Study in Pakistan , 2013, PloS one.

[72]  Xin Yang,et al.  Occurrence and fate of PPCPs and correlations with water quality parameters in urban riverine waters of the Pearl River Delta, South China , 2013, Environmental Science and Pollution Research.

[73]  Patrick Drogui,et al.  Tetracycline antibiotics in the environment: a review , 2013, Environmental Chemistry Letters.

[74]  J. Carrera,et al.  Occurrence of 95 pharmaceuticals and transformation products in urban groundwaters underlying the metropolis of Barcelona, Spain. , 2013, Environmental pollution.

[75]  A. P. Williams,et al.  The role of the natural environment in the emergence of antibiotic resistance in gram-negative bacteria. , 2013, The Lancet. Infectious diseases.

[76]  Sung-Chul Kim,et al.  Veterinary antibiotics contamination in water, sediment, and soil near a swine manure composting facility , 2013, Environmental Earth Sciences.

[77]  Magali Casellas,et al.  Integron Involvement in Environmental Spread of Antibiotic Resistance , 2012, Front. Microbio..

[78]  I. Xagoraraki,et al.  Correlation of tetracycline and sulfonamide antibiotics with corresponding resistance genes and resistant bacteria in a conventional municipal wastewater treatment plant. , 2012, The Science of the total environment.

[79]  D. Lapworth,et al.  Emerging organic contaminants in groundwater: A review of sources, fate and occurrence. , 2012, Environmental pollution.

[80]  C. Ateba,et al.  Detection of Enterococcus species in groundwater from some rural communities in the Mmabatho area, South Africa: A risk analysis , 2011 .

[81]  L. Ma,et al.  Effects of pH and ionic strength on sulfamethoxazole and ciprofloxacin transport in saturated porous media. , 2011, Journal of contaminant hydrology.

[82]  R. Aminov Horizontal Gene Exchange in Environmental Microbiota , 2011, Front. Microbio..

[83]  S. Bardy,et al.  Comparison of the Transport of Tetracycline-Resistant and Tetracycline-Susceptible Escherichia coli Isolated from Lake Michigan , 2011, Water, air, and soil pollution.

[84]  S. Bartelt-Hunt,et al.  Occurrence of steroid hormones and antibiotics in shallow groundwater impacted by livestock waste control facilities. , 2011, Journal of contaminant hydrology.

[85]  Damià Barceló,et al.  Application of fully automated online solid phase extraction-liquid chromatography-electrospray-tandem mass spectrometry for the determination of sulfonamides and their acetylated metabolites in groundwater , 2011, Analytical and bioanalytical chemistry.

[86]  R M Stuetz,et al.  Fate of antibiotics during municipal water recycling treatment processes. , 2010, Water research.

[87]  Heather K. Allen,et al.  Call of the wild: antibiotic resistance genes in natural environments , 2010, Nature Reviews Microbiology.

[88]  J. Davies,et al.  Origins and Evolution of Antibiotic Resistance , 1996, Microbiology and Molecular Biology Reviews.

[89]  D. Moher,et al.  Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. , 2010, International journal of surgery.

[90]  Mats Tysklind,et al.  Contamination of surface, ground, and drinking water from pharmaceutical production , 2009, Environmental toxicology and chemistry.

[91]  Klaus Kümmerer,et al.  Antibiotics in the aquatic environment--a review--part I. , 2009, Chemosphere.

[92]  Tong Zhang,et al.  Antibiotic resistance genes in water environment , 2009, Applied Microbiology and Biotechnology.

[93]  Thomas Wintgens,et al.  Quantitative PCR Monitoring of Antibiotic Resistance Genes and Bacterial Pathogens in Three European Artificial Groundwater Recharge Systems , 2008, Applied and Environmental Microbiology.

[94]  R. Surampalli,et al.  Effects of ionic strength, temperature, and pH on degradation of selected antibiotics. , 2008, Journal of environmental quality.

[95]  S. Koike,et al.  Monitoring and Source Tracking of Tetracycline Resistance Genes in Lagoons and Groundwater Adjacent to Swine Production Facilities over a 3-Year Period , 2007, Applied and Environmental Microbiology.

[96]  F. Curriero,et al.  Antibiotic-Resistant Enterococci and Fecal Indicators in Surface Water and Groundwater Impacted by a Concentrated Swine Feeding Operation , 2007, Environmental health perspectives.

[97]  K. Kümmerer,et al.  Ultimate biodegradation and elimination of antibiotics in inherent tests. , 2007, Chemosphere.

[98]  S. Koike,et al.  Tetracycline Residues and Tetracycline Resistance Genes in Groundwater Impacted by Swine Production Facilities , 2006, Animal biotechnology.

[99]  Ramunas Stepanauskas,et al.  Co-selection of antibiotic and metal resistance. , 2006, Trends in microbiology.

[100]  O. Sahin,et al.  Enhanced in vivo fitness of fluoroquinolone-resistant Campylobacter jejuni in the absence of antibiotic selection pressure. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[101]  David L. Smith,et al.  Animal antibiotic use has an early but important impact on the emergence of antibiotic resistance in human commensal bacteria , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[102]  R. Mackie,et al.  Occurrence and Diversity of Tetracycline Resistance Genes in Lagoons and Groundwater Underlying Two Swine Production Facilities , 2001, Applied and Environmental Microbiology.

[103]  S. Alvarez-Elcoro,et al.  The macrolides: erythromycin, clarithromycin, and azithromycin. , 1999, Mayo Clinic proceedings.

[104]  M. Fayez,et al.  Incidence of antibiotic resistant bacteria in underground water , 1988 .