TGF-regulates the mechanical properties and composition of bone matrix

*Graduate Program in Oral and Craniofacial Sciences, Departments of †Preventive and Restorative Dental Sciences and **Cell and Tissue Biology, and Programs in Cell Biology and Development, University of California, San Francisco, CA 94143; ‡Materials Sciences Division, Lawrence Berkeley National Laboratory, and Department of Materials Science and Engineering, University of California, Berkeley, CA 94720; §Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710; and ¶Department of Molecular Oncology, Genentech, South San Francisco, CA 94080