Transport of CSF antibodies to Galpha subunits across neural membranes requires binding to the target protein and protein kinase C activity.

[1]  P. Sánchez-Blázquez,et al.  delta Opioid receptor subtypes activate inositol-signaling pathways in the production of antinociception. , 1998, The Journal of pharmacology and experimental therapeutics.

[2]  H. Rasmussen,et al.  Identification of Caveolin and Caveolin-Related Proteins in the Brain , 1997, The Journal of Neuroscience.

[3]  P. Panegyres.  The amyloid precursor protein gene: a neuropeptide gene with diverse functions in the central nervous system , 1997, Neuropeptides.

[4]  P. Sánchez-Blázquez,et al.  GX/Z Is Regulated by μ But Not δ Opioid Receptors in the Stimulation of the Low Km GTPase Activity in Mouse Periaqueductal Grey Matter , 1997 .

[5]  A. García-España,et al.  Opioids binding mu and delta receptors exhibit diverse efficacy in the activation of Gi2 and G(x/z) transducer proteins in mouse periaqueductal gray matter. , 1997, The Journal of pharmacology and experimental therapeutics.

[6]  A. García-España,et al.  Antisense oligodeoxynucleotides to opioid mu and delta receptors reduced morphine dependence in mice: role of delta-2 opioid receptors. , 1997, The Journal of pharmacology and experimental therapeutics.

[7]  R. Parton,et al.  Caveolae and caveolins. , 1996, Current opinion in cell biology.

[8]  G. Pasternak,et al.  Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits. , 1996, Molecular pharmacology.

[9]  A. Prochiantz,et al.  Axonal Amyloid Precursor Protein Expressed by Neurons in Vitro Is Present in a Membrane Fraction with Caveolae-like Properties (*) , 1996, The Journal of Biological Chemistry.

[10]  V. Chekhonin,et al.  Transport of hydrophobized fragments of antibodies through the blood–brain barrier , 1995, Neuroreport.

[11]  A. García-España,et al.  In vivo injection of antisense oligodeoxynucleotides to G alpha subunits and supraspinal analgesia evoked by mu and delta opioid agonists. , 1995, The Journal of pharmacology and experimental therapeutics.

[12]  G. Pasternak,et al.  Differential blockade of morphine and morphine-6β-glucuronide analgesia by antisense oligodeoxynucleotides directed against MOR-1 and G-protein α subunits in rats , 1995, Neuroscience Letters.

[13]  J. Helms.  Role of heterotrimeric GTP binding proteins in vesicular protein transport: indications for both classical and alternative G protein cycles , 1995, FEBS letters.

[14]  F. Vogel,et al.  VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro. , 1995, Molecular biology of the cell.

[15]  M. Lisanti,et al.  Evidence for a Regulated Interaction between Heterotrimeric G Proteins and Caveolin , 1995, The Journal of Biological Chemistry.

[16]  A. Gewirtz,et al.  Binding, uptake, and intracellular trafficking of phosphorothioate-modified oligodeoxynucleotides. , 1995, The Journal of clinical investigation.

[17]  R. Parton,et al.  Regulated internalization of caveolae , 1994, The Journal of cell biology.

[18]  M. Lisanti,et al.  Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis. , 1994, Trends in cell biology.

[19]  R. Raffa,et al.  G-protein antisense oligodeoxyribonucleotides and mu-opioid supraspinal antinociception. , 1994, European journal of pharmacology.

[20]  M. Matthay,et al.  Effect of endocytosis inhibitors on alveolar clearance of albumin, immunoglobulin G, and SP-A in rabbits. , 1994, The American journal of physiology.

[21]  L. Pitts,et al.  Immunocytochemical localization of immunoglobulins in the rat brain: Relationship to the blood‐brain barrier , 1994, The Journal of comparative neurology.

[22]  P. Milburn,et al.  Retrograde Axonal Transport of the α‐Subunit of the GTP‐binding Protein Gz in Mouse Sciatic Nerve: a Potential Pathway for Signal Transduction In Neurons , 1994, The European journal of neuroscience.

[23]  M. Aridor,et al.  Activation of exocytosis by the heterotrimeric G protein Gi3. , 1993, Science.

[24]  M. Lisanti,et al.  Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells , 1993, The Journal of cell biology.

[25]  S. Rotenberg,et al.  Dynamics of the internalization of phosphodiester oligodeoxynucleotides in HL60 cells. , 1993, Biochemistry.

[26]  J DeFelipe,et al.  A simple and reliable method for correlative light and electron microscopic studies. , 1993, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[27]  U. Bickel,et al.  Pharmacologic effects in vivo in brain by vector-mediated peptide drug delivery. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[28]  I. Nishimoto,et al.  Alzheimer amyloid protein precursor complexes with brain GTP-binding protein Go , 1993, Nature.

[29]  F. Bloom,et al.  Blood-brain barrier penetration and in vivo activity of an NGF conjugate. , 1993, Science.

[30]  W. Huttner,et al.  Multiple trimeric G‐proteins on the trans‐Golgi network exert stimulatory and inhibitory effects on secretory vesicle formation. , 1992, The EMBO journal.

[31]  N. Aronin,et al.  The subcellular localization of the G-protein Gi alpha in the basal ganglia reveals its potential role in both signal transduction and vesicle trafficking , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[32]  S. Coulter,et al.  Heterotrimeric G proteins in synaptoneurosome membranes are crosslinked by p-phenylenedimaleimide, yielding structures comparable in size to crosslinked tubulin and F-actin. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[33]  J. Bockaert,et al.  Differential G protein-mediated coupling of D2 dopamine receptors to K+ and Ca2+ currents in rat anterior pituitary cells , 1992, Neuron.

[34]  G. Schultz,et al.  Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents , 1991, Nature.

[35]  G. Schultz,et al.  Evidence for opioid receptor-mediated activation of the G-proteins, Go and Gi2, in membranes of neuroblastoma x glioma (NG108-15) hybrid cells. , 1991, The Journal of biological chemistry.

[36]  M. Crouch.  Growth factor‐induced cell division is paralleled by translocation of Giα to the nucleus , 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[37]  H. Davson,et al.  A saturable mechanism for transport of immunoglobulin G across the blood-brain barrier of the guinea pig , 1990, Experimental Neurology.

[38]  M. Rasenick,et al.  Tubulin binds specifically to the signal-transducing proteins, Gs alpha and Gi alpha 1. , 1990, The Journal of biological chemistry.

[39]  W. Simonds,et al.  Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[40]  V. Vlassov,et al.  Mechanism of oligonucleotide uptake by cells: involvement of specific receptors? , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[41]  J. Thyberg,et al.  Monensin and chloroquine inhibit transfer to lysosomes of endocytosed macromolecules in cultured mouse peritoneal macrophages. , 1989, European journal of cell biology.

[42]  D. A. Brown,et al.  Antibodies to the GTP binding protein, Go, antagonize noradrenaline-induced calcium current inhibition in NG108-15 hybrid cells , 1989, Neuron.

[43]  W. Pardridge,et al.  Blood-brain barrier transport of cationized immunoglobulin G: enhanced delivery compared to native protein. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[44]  J. Bockaert,et al.  Apical localization of the alpha subunit of GTP-binding protein Go in choroidal and ciliated ependymocytes [published erratum appears in J Neurosci 1989 Apr;9(4):following Table of Contents] , 1989, Journal of Neuroscience.

[45]  F. Marks,et al.  Molecular cloning of mouse protein kinase C (PKC) cDNA from Swiss 3T3 fibroblasts. , 1988, Gene.

[46]  J. Cooper,et al.  Effects of cytochalasin and phalloidin on actin , 1987, The Journal of cell biology.

[47]  Y. Nishizuka,et al.  Expression and properties of two types of protein kinase C: alternative splicing from a single gene. , 1987, Science.

[48]  Y. Nishizuka,et al.  Two types of complementary DNAs of rat brain protein kinase C , 1986, FEBS letters.

[49]  R. Kriz,et al.  Cloning and expression of multiple protein kinase C cDNAs , 1986, Cell.

[50]  R. Klausner,et al.  Receptor-mediated endocytosis of transferrin and the uptake of fe in K562 cells: identification of a nonlysosomal acidic compartment. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[51]  T. Katada,et al.  Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[52]  I. Pastan,et al.  Localization of serum-derived α2 macroglobulin in cultured cells and decrease after moloney sarcoma virus transformation , 1977, Cell.

[53]  K. Kristensson,et al.  Retrograde axonal transport of protein. , 1971, Brain research.

[54]  T. Reese,et al.  JUNCTIONS BETWEEN INTIMATELY APPOSED CELL MEMBRANES IN THE VERTEBRATE BRAIN , 1969, The Journal of cell biology.

[55]  G. D. Pappas,et al.  Distribution of Colloidal Particles in Extracellular Space and Synaptic Cleft Substance of Mammalian Cerebral Cortex , 1966, Nature.

[56]  P. Sánchez-Blázquez,et al.  μ-OPIOID RECEPTORS REGULATE PERTUSSIS TOXIN-INSENSITIVE Gx/z- AND Gq-TRANSDUCER PROTEINS IN THE PRODUCTION OF ANALGESIA IN THE MOUSE , 1995 .

[57]  J. Garzón.  Cellular Transduction Regulated by μ- and δ-Opioid Receptors in Supraspinal Analgesia: GTP Binding Regulatory Proteins as Pharmacological Targets , 1995 .

[58]  P. Sánchez-Blázquez,et al.  Dissimilar efficacy of opioids to produce mu-mediated analgesia: role of Gx/z and Gi2 transducer proteins. , 1994, Life sciences.

[59]  P. Sánchez-Blázquez,et al.  GX/Z and Gi2 transducer proteins on μ/δ opioid-mediated supraspinal antinociception , 1993 .

[60]  G. Nilaver,et al.  Localization patterns for immunoglobulins and albumins in the brain suggest diverse mechanisms for their transport across the blood-brain barrier (BBB). , 1992, Progress in brain research.

[61]  I. Pastan,et al.  Morphologic characterization of the pathway of transferrin endocytosis and recycling in human KB cells. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[62]  M. Brightman.  The intracerebral movement of proteins injected into blood and cerebrospinal fluid of mice. , 1968, Progress in brain research.