Gut Microbiota is an Impact Factor based on the Brain-Gut Axis to Alzheimer’s Disease: A Systematic Review

[1]  Ying Han,et al.  Combination of gut microbiota and plasma amyloid-β as a potential index for identifying preclinical Alzheimer’s disease: a cross-sectional analysis from the SILCODE study , 2022, Alzheimer's research & therapy.

[2]  I. Domitrz,et al.  The Microbiota-Gut-Brain Axis as a Key to Neuropsychiatric Disorders: A Mini Review , 2021, Journal of clinical medicine.

[3]  M. Oh,et al.  Transplantation of gut microbiota derived from Alzheimer’s disease mouse model impairs memory function and neurogenesis in C57BL/6 mice , 2021, Brain, Behavior, and Immunity.

[4]  Seil Sohn,et al.  Transplantation of tauroursodeoxycholic acid–inducing M2‐phenotype macrophages promotes an anti‐neuroinflammatory effect and functional recovery after spinal cord injury in rats , 2021, Cell proliferation.

[5]  Huidong Tang,et al.  Inflammatory pathways in Alzheimer’s disease mediated by gut microbiota , 2021, Ageing Research Reviews.

[6]  K. Kurz,et al.  The Immunopathogenesis of Alzheimer’s Disease Is Related to the Composition of Gut Microbiota , 2021, Nutrients.

[7]  M. Solas,et al.  Dysbiosis and Alzheimer’s Disease: Cause or Treatment Opportunity? , 2021, Cellular and Molecular Neurobiology.

[8]  P. Schulz,et al.  The impact of the microbiota-gut-brain axis on Alzheimer's disease pathophysiology. , 2020, Pharmacological research.

[9]  S. Mazmanian,et al.  The gut microbiota–brain axis in behaviour and brain disorders , 2020, Nature Reviews Microbiology.

[10]  Expression of Concern: Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer's Disease: A Randomized, Double-Blind and Controlled Trial , 2020, Frontiers in Aging Neuroscience.

[11]  O. Pedersen,et al.  Gut microbiota in human metabolic health and disease , 2020, Nature Reviews Microbiology.

[12]  Elaine Hillesheim,et al.  Probiotics for dementia: a systematic review and meta-analysis of randomized controlled trials. , 2020, Nutrition reviews.

[13]  S. Xiao,et al.  Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization , 2020, Stem Cell Research & Therapy.

[14]  Youlin Zhang,et al.  The protective effects of walnut green husk polysaccharide on liver injury, vascular endothelial dysfunction and disorder of gut microbiota in high fructose-induced mice. , 2020, International journal of biological macromolecules.

[15]  E. Elinav,et al.  Interaction between microbiota and immunity in health and disease , 2020, Cell Research.

[16]  R. Friedland,et al.  What Are the Molecular Mechanisms by Which Functional Bacterial Amyloids Influence Amyloid Beta Deposition and Neuroinflammation in Neurodegenerative Disorders? , 2020, International journal of molecular sciences.

[17]  B. Polis,et al.  Role of the metabolism of branched-chain amino acids in the development of Alzheimer's disease and other metabolic disorders , 2020, Neural regeneration research.

[18]  P. Wilmes,et al.  The microbiome-gut-brain axis in acute and chronic brain diseases , 2019, Current Opinion in Neurobiology.

[19]  G. Rossi,et al.  Gut microbiota manipulation through probiotics oral administration restores glucose homeostasis in a mouse model of Alzheimer's disease , 2019, Neurobiology of Aging.

[20]  P. Xu,et al.  Modified Huang-Lian-Jie-Du Decoction Ameliorates Aβ Synaptotoxicity in a Murine Model of Alzheimer's Disease , 2019, Oxidative medicine and cellular longevity.

[21]  L. Buée,et al.  NLRP3 inflammasome activation drives tau pathology , 2019, Nature.

[22]  Kieran Rea,et al.  The Microbiota-Gut-Brain Axis. , 2019, Physiological reviews.

[23]  Huidong Tang,et al.  Mild cognitive impairment has similar alterations as Alzheimer's disease in gut microbiota , 2019, Alzheimer's & Dementia.

[24]  V. D’Argenio,et al.  Microbiome Influence in the Pathogenesis of Prion and Alzheimer’s Diseases , 2019, International journal of molecular sciences.

[25]  Jian Ding,et al.  Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression , 2019, Cell Research.

[26]  Molly Fox,et al.  Alzheimer's disease and symbiotic microbiota: an evolutionary medicine perspective , 2019, Annals of the New York Academy of Sciences.

[27]  B. Vervliet,et al.  The role of short-chain fatty acids in microbiota–gut–brain communication , 2019, Nature Reviews Gastroenterology & Hepatology.

[28]  Lanjuan Li,et al.  Altered microbiomes distinguish Alzheimer’s disease from amnestic mild cognitive impairment and health in a Chinese cohort , 2019, Brain, Behavior, and Immunity.

[29]  M. Heneka,et al.  Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome , 2019, The EMBO journal.

[30]  H. Morita,et al.  Fecal metabolite of a gnotobiotic mouse transplanted with gut microbiota from a patient with Alzheimer’s disease , 2019, Bioscience, biotechnology, and biochemistry.

[31]  D. Fuchs,et al.  Commentary: Does Severity of Alzheimer's Disease Contribute to Its Responsiveness to Modifying Gut Microbiota? A Double Blind Clinical Trial , 2019, Front. Neurol..

[32]  M. Di Mauro,et al.  Neuropsychiatric Disturbances and Diabetes Mellitus: The Role of Oxidative Stress , 2019, Oxidative medicine and cellular longevity.

[33]  Y. Kiriyama,et al.  The Biosynthesis, Signaling, and Neurological Functions of Bile Acids , 2019, Biomolecules.

[34]  J. Hort,et al.  Antibiotics, gut microbiota, and Alzheimer’s disease , 2019, Journal of neuroinflammation.

[35]  A. O. Sasmita,et al.  Modification of the gut microbiome to combat neurodegeneration , 2019, Reviews in the neurosciences.

[36]  G. Guillemin,et al.  Microbiota Alterations in Alzheimer’s Disease: Involvement of the Kynurenine Pathway and Inflammation , 2019, Neurotoxicity Research.

[37]  A. Fagan,et al.  Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease , 2019, Alzheimer's & Dementia.

[38]  M. Bostancıklıoğlu The role of gut microbiota in pathogenesis of Alzheimer's disease , 2019, Journal of applied microbiology.

[39]  Erratum to “Altered bile acid profile associates with cognitive impairment in Alzheimer’s disease—An emerging role for gut microbiome” [Alzheimer’s & Dementia 2019;15:76-92.] , 2019, Alzheimer's & Dementia.

[40]  S. Pongor,et al.  Exercise and probiotics attenuate the development of Alzheimer's disease in transgenic mice: Role of microbiome , 2019, Experimental Gerontology.

[41]  M. Othman,et al.  Overview of Bile Acids Signaling and Perspective on the Signal of Ursodeoxycholic Acid, the Most Hydrophilic Bile Acid, in the Heart , 2018, Biomolecules.

[42]  S. An,et al.  Gut Microbiota and Their Neuroinflammatory Implications in Alzheimer’s Disease , 2018, Nutrients.

[43]  R. Malkani,et al.  Sleep and circadian rhythm disruption and stress intersect in Alzheimer's disease , 2018, Neurobiology of Stress.

[44]  O. Forlenza,et al.  Relevance of gutmicrobiota in cognition, behaviour and Alzheimer’s disease , 2018, Pharmacological research.

[45]  Yong-ming Yao,et al.  Autophagy and proinflammatory cytokines: Interactions and clinical implications. , 2018, Cytokine & growth factor reviews.

[46]  J. Gostner,et al.  Probiotic Supplementation in Patients with Alzheimer’s Dementia - An Explorative Intervention Study , 2018, Current Alzheimer research.

[47]  M. Clerici,et al.  The Gut-Brain Axis in Alzheimer’s Disease and Omega-3. A Critical Overview of Clinical Trials , 2018, Nutrients.

[48]  T. R. Licht,et al.  Microbial tryptophan catabolites in health and disease , 2018, Nature Communications.

[49]  M. Salami,et al.  Does Severity of Alzheimer's Disease Contribute to Its Responsiveness to Modifying Gut Microbiota? A Double Blind Clinical Trial , 2018, Front. Neurol..

[50]  R. Knight,et al.  Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism , 2018, Nature Communications.

[51]  K. Kasuga,et al.  Production of d-Branched-Chain Amino Acids by Lactic Acid Bacteria Carrying Homologs to Isoleucine 2-Epimerase of Lactobacillus buchneri , 2018, Front. Microbiol..

[52]  Sterling C. Johnson,et al.  THE GUT MICROBIOTA-DERIVED METABOLITE TRIMETHYLAMINE N-OXIDE (TMAO) IS ELEVATED IN ALZHEIMER’S DISEASE , 2018, Alzheimer's & Dementia.

[53]  M. Sánchez-Niño,et al.  Impact of Altered Intestinal Microbiota on Chronic Kidney Disease Progression , 2018, Toxins.

[54]  Charles Nkufi Tango,et al.  Human microbiome restoration and safety. , 2018, International journal of medical microbiology : IJMM.

[55]  H. Frieling,et al.  Alcohol, microbiome, and their effect on psychiatric disorders , 2018, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[56]  S. Hazen,et al.  Development of a gut microbe-targeted non-lethal therapeutic to inhibit thrombosis potential , 2018, Nature Medicine.

[57]  Marco Prinz,et al.  Microglial control of astrocytes in response to microbial metabolites , 2018, Nature.

[58]  Mingming Zhao,et al.  Trimethylamine‐N‐oxide promotes brain aging and cognitive impairment in mice , 2018, Aging cell.

[59]  M. Battino,et al.  Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer's disease: A focus on human studies. , 2018, Pharmacological research.

[60]  Emeran A. Mayer,et al.  The Brain-Gut-Microbiome Axis , 2018, Cellular and molecular gastroenterology and hepatology.

[61]  Z. Savin,et al.  Smoking and the intestinal microbiome , 2018, Archives of Microbiology.

[62]  R. Adan,et al.  Microbiota in obesity: interactions with enteroendocrine, immune and central nervous systems , 2018, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[63]  Fu-Huang Lin,et al.  Anti-herpetic Medications and Reduced Risk of Dementia in Patients with Herpes Simplex Virus Infections—a Nationwide, Population-Based Cohort Study in Taiwan , 2018, Neurotherapeutics.

[64]  F. Marotta,et al.  Possible correlation between gut microbiota and immunity among healthy middle-aged and elderly people in southwest China , 2018, Gut Pathogens.

[65]  Youping Deng,et al.  Strategy for an Association Study of the Intestinal Microbiome and Brain Metabolome Across the Lifespan of Rats. , 2018, Analytical chemistry.

[66]  C. Mancuso,et al.  Alzheimer's disease and gut microbiota modifications: The long way between preclinical studies and clinical evidence , 2017, Pharmacological research.

[67]  M. Heneka,et al.  Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease , 2017, Nature.

[68]  J. Baker,et al.  An overview of the effect of probiotics and exercise on mood and associated health conditions , 2017, Critical reviews in food science and nutrition.

[69]  Matthew R Chapman,et al.  The role of microbial amyloid in neurodegeneration , 2017, PLoS pathogens.

[70]  J. Cryan,et al.  The microbiome as a key regulator of brain, behavior and immunity: Commentary on the 2017 named series , 2017, Brain, Behavior, and Immunity.

[71]  M. Oliveri,et al.  A New Proposal for the Pathogenic Mechanism of Non-Coeliac/Non-Allergic Gluten/Wheat Sensitivity: Piecing Together the Puzzle of Recent Scientific Evidence , 2017, Nutrients.

[72]  Sterling C. Johnson,et al.  Gut microbiome alterations in Alzheimer’s disease , 2017, Scientific Reports.

[73]  E. Quigley Microbiota-Brain-Gut Axis and Neurodegenerative Diseases , 2017, Current Neurology and Neuroscience Reports.

[74]  Michael W. Weiner,et al.  Metabolic network failures in Alzheimer's disease: A biochemical road map , 2017, Alzheimer's & Dementia.

[75]  K. Lesch,et al.  Effect of aging and Alzheimer's disease-like pathology on brain monoamines in mice , 2017, Neurochemistry International.

[76]  J. Kaczmarek,et al.  Complex interactions of circadian rhythms, eating behaviors, and the gastrointestinal microbiota and their potential impact on health , 2017, Nutrition reviews.

[77]  W. Lukiw,et al.  Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus , 2017, Front. Cell. Infect. Microbiol..

[78]  G. Rossi,et al.  Microbiota modulation counteracts Alzheimer’s disease progression influencing neuronal proteolysis and gut hormones plasma levels , 2017, Scientific Reports.

[79]  J. Griffin,et al.  Amino Acid Catabolism in Alzheimer's Disease Brain: Friend or Foe? , 2017, Oxidative medicine and cellular longevity.

[80]  G. Frisoni,et al.  Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly , 2017, Neurobiology of Aging.

[81]  H. Flint,et al.  Formation of propionate and butyrate by the human colonic microbiota. , 2017, Environmental microbiology.

[82]  C. Jobin,et al.  Microbiota as a mediator of cancer progression and therapy , 2017, Translational research : the journal of laboratory and clinical medicine.

[83]  S. Ash,et al.  Neutralization Versus Reinforcement of Proinflammatory Cytokines to Arrest Autoimmunity in Type 1 Diabetes , 2017, Clinical Reviews in Allergy & Immunology.

[84]  V. Danilenko,et al.  GABA production and structure of gadB/gadC genes in Lactobacillus and Bifidobacterium strains from human microbiota. , 2016, Anaerobe.

[85]  B. Zhu,et al.  Human gut microbiota: the links with dementia development , 2016, Protein & Cell.

[86]  T. Murphy,et al.  Mapping synaptic glutamate transporter dysfunction in vivo to regions surrounding Aβ plaques by iGluSnFR two-photon imaging , 2016, Nature Communications.

[87]  M. Salami,et al.  Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer's Disease: A Randomized, Double-Blind and Controlled Trial , 2016, Front. Aging Neurosci..

[88]  M. Battino,et al.  Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease. , 2016, Nutrition reviews.

[89]  Rong Xu,et al.  Towards understanding brain-gut-microbiome connections in Alzheimer’s disease , 2016, BMC Systems Biology.

[90]  D. Holtzman,et al.  Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer’s disease , 2016, Scientific Reports.

[91]  Junjie Yu,et al.  Clostridium butyricum attenuates cerebral ischemia/reperfusion injury in diabetic mice via modulation of gut microbiota , 2016, Brain Research.

[92]  Luc Buée,et al.  AMP-activated protein kinase modulates tau phosphorylation and tau pathology in vivo , 2016, Scientific Reports.

[93]  N. Pochet,et al.  Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and CNS inflammation via the aryl hydrocarbon receptor , 2016, Nature Medicine.

[94]  G. Xie,et al.  The Brain Metabolome of Male Rats across the Lifespan , 2016, Scientific Reports.

[95]  Arthur James Cooper,et al.  Central Role of Glutamate Metabolism in the Maintenance of Nitrogen Homeostasis in Normal and Hyperammonemic Brain , 2016, Biomolecules.

[96]  Ron Milo,et al.  Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans , 2016, Cell.

[97]  R. Gold,et al.  Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine. , 2015, Immunity.

[98]  T. Dinan,et al.  Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders , 2015, Front. Cell. Neurosci..

[99]  C. Calandra,et al.  The Role of Oxidative Damage in the Pathogenesis and Progression of Alzheimer's Disease and Vascular Dementia , 2015, Oxidative medicine and cellular longevity.

[100]  J. Bienenstock,et al.  Microbiota and the gut-brain axis. , 2015, Nutrition reviews.

[101]  Richard A Flavell,et al.  Immune-microbiota interactions in health and disease. , 2015, Clinical immunology.

[102]  I. Amit,et al.  Host microbiota constantly control maturation and function of microglia in the CNS , 2015, Nature Neuroscience.

[103]  G. Gambassi,et al.  How the Intricate Interaction among Toll-Like Receptors, Microbiota, and Intestinal Immunity Can Influence Gastrointestinal Pathology , 2015, Journal of immunology research.

[104]  S. Mazmanian,et al.  Review Control of Brain Development, Function, and Behavior by the Microbiome Figure 2. Microbiome Influence on Bbb Integrity , 2022 .

[105]  Rustem F. Ismagilov,et al.  Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis , 2015, Cell.

[106]  G. Szabo Gut-liver axis in alcoholic liver disease. , 2015, Gastroenterology.

[107]  M. Lynch,et al.  Modulation of Intestinal Microbiota by the Probiotic VSL#3 Resets Brain Gene Expression and Ameliorates the Age-Related Deficit in LTP , 2014, PloS one.

[108]  Yong Jeong,et al.  GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease , 2014, Nature Medicine.

[109]  Matthew McMillin,et al.  Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms. , 2014, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[110]  Yan Wang,et al.  The role of microbiome in central nervous system disorders , 2014, Brain, Behavior, and Immunity.

[111]  M. Levine,et al.  Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population. , 2014, Cell metabolism.

[112]  J. Cryan,et al.  Microbial genes, brain & behaviour – epigenetic regulation of the gut–brain axis , 2014, Genes, brain, and behavior.

[113]  J. Petrosino,et al.  Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders , 2013, Cell.

[114]  S. Zeisel,et al.  Alteration of bile acid metabolism in the rat induced by chronic ethanol consumption , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[115]  L. Groot,et al.  Literature review on the role of dietary protein and amino acids in cognitive functioning and cognitive decline , 2013, Amino Acids.

[116]  B. Naliboff,et al.  Consumption of fermented milk product with probiotic modulates brain activity. , 2013, Gastroenterology.

[117]  P. Edwards,et al.  Pleiotropic roles of bile acids in metabolism. , 2013, Cell metabolism.

[118]  R. D'Hooge,et al.  Tauroursodeoxycholic acid (TUDCA) supplementation prevents cognitive impairment and amyloid deposition in APP/PS1 mice , 2013, Neurobiology of Disease.

[119]  M. Surette,et al.  The interplay between the intestinal microbiota and the brain , 2012, Nature Reviews Microbiology.

[120]  T. Dinan,et al.  Mind-altering Microorganisms: the Impact of the Gut Microbiota on Brain and Behaviour , 2022 .

[121]  R. D'Hooge,et al.  TUDCA, a Bile Acid, Attenuates Amyloid Precursor Protein Processing and Amyloid-β Deposition in APP/PS1 Mice , 2012, Molecular Neurobiology.

[122]  J. Miklossy,et al.  Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria , 2011, Journal of Neuroinflammation.

[123]  H. Forssberg,et al.  Normal gut microbiota modulates brain development and behavior , 2011, Proceedings of the National Academy of Sciences.

[124]  L. Putignani,et al.  Gut microbiota, lipopolysaccharides, and innate immunity in the pathogenesis of obesity and cardiovascular risk. , 2010, Endocrine reviews.

[125]  G. D’Antona,et al.  Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice. , 2010, Cell metabolism.

[126]  B. Finlay,et al.  Gut microbiota in health and disease. , 2010, Physiological reviews.

[127]  P. Bork,et al.  A human gut microbial gene catalogue established by metagenomic sequencing , 2010, Nature.

[128]  R. Rao Occludin Phosphorylation in Regulation of Epithelial Tight Junctions , 2009, Annals of the New York Academy of Sciences.

[129]  MA Wozniak,et al.  Herpes simplex virus type 1 DNA is located within Alzheimer's disease amyloid plaques , 2009, The Journal of pathology.

[130]  R. Bibiloni,et al.  Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice , 2008, Diabetes.

[131]  Gary Kay,et al.  Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder , 2006, British journal of pharmacology.

[132]  E. Purdom,et al.  Diversity of the Human Intestinal Microbial Flora , 2005, Science.