Optogenetic examination identifies a context-specific role for orexins/hypocretins in anxiety-related behavior

[1]  S. Bhatnagar,et al.  Orexins/hypocretins act in the posterior paraventricular thalamic nucleus during repeated stress to regulate facilitation to novel stress. , 2011, Endocrinology.

[2]  Yonghui Li,et al.  Orexins in the paraventricular nucleus of the thalamus mediate anxiety-like responses in rats , 2010, Psychopharmacology.

[3]  R. Valentino,et al.  Individual differences in reactivity to social stress predict susceptibility and resilience to a depressive phenotype: role of corticotropin-releasing factor. , 2010, Endocrinology.

[4]  A. Shekhar,et al.  A KEY ROLE FOR OREXIN IN PANIC ANXIETY , 2009, Nature Medicine.

[5]  Yonghui Li,et al.  Orexin-A acts on the paraventricular nucleus of the midline thalamus to inhibit locomotor activity in rats , 2009, Pharmacology Biochemistry and Behavior.

[6]  S. Floresco,et al.  Orexin A/Hypocretin-1 Selectively Promotes Motivation for Positive Reinforcers , 2009, The Journal of Neuroscience.

[7]  H. Randeva,et al.  Orexins stimulate steroidogenic acute regulatory protein expression through multiple signaling pathways in human adrenal H295R cells. , 2008, Endocrinology.

[8]  S. Chattarji,et al.  Stress-induced changes in sleep and associated neuronal activity in rat hippocampus and amygdala , 2008, Neuroscience.

[9]  A. Adamantidis,et al.  Physiological arousal: a role for hypothalamic systems , 2008, Cellular and Molecular Life Sciences.

[10]  南部 忠洋.  Distribution of orexin neurons in the adult rat brain , 2007 .

[11]  S. Kaur,et al.  The development of hypocretin (OREXIN) deficiency in hypocretin/ataxin-3 transgenic rats , 2007, Neuroscience.

[12]  H. Soya,et al.  Inhibitory effects of an orexin-2 receptor antagonist on orexin A- and stress-induced ACTH responses in conscious rats , 2007, Neuroscience Research.

[13]  Dimitris N. Metaxas,et al.  Novel method for high-throughput phenotyping of sleep in mice. , 2007, Physiological genomics.

[14]  G. Kirouac,et al.  Orexin (hypocretin) innervation of the paraventricular nucleus of the thalamus , 2005, Brain Research.

[15]  A. Ferguson,et al.  Non-sleep effects of hypocretin/orexin. , 2005, Sleep medicine reviews.

[16]  H. Ogura,et al.  Orexin-A (hypocretin-1) is possibly involved in generation of anxiety-like behavior , 2005, Brain Research.

[17]  Shelagh Wilson,et al.  The sustainability of interactions between the orexin-1 receptor and beta-arrestin-2 is defined by a single C-terminal cluster of hydroxy amino acids and modulates the kinetics of ERK MAPK regulation. , 2005, The Biochemical journal.

[18]  R. Benca,et al.  Comparison of hypocretin/orexin and melanin-concentrating hormone neurons and axonal projections in the embryonic and postnatal rat brain , 2004, Journal of Chemical Neuroanatomy.

[19]  H. Randeva,et al.  Orexin receptors and G-protein coupling: evidence for another "promiscuous" seven transmembrane domain receptor. , 2003, Journal of pharmacological sciences.

[20]  A. Ferguson,et al.  Orexin actions in hypothalamic paraventricular nucleus: physiological consequences and cellular correlates , 2002, Regulatory Peptides.

[21]  A. Kelley,et al.  Wake-promoting and sleep-suppressing actions of hypocretin (orexin): basal forebrain sites of action , 2001, Neuroscience.

[22]  C. Saper,et al.  Differential expression of orexin receptors 1 and 2 in the rat brain , 2001, The Journal of comparative neurology.

[23]  M. Nakazato,et al.  Centrally administered orexin/hypocretin activates HPA axis in rats , 2000, Neuroreport.

[24]  M. I. Smith,et al.  Orexin A activates locus coeruleus cell firing and increases arousal in the rat. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[25]  M. Ghatei,et al.  Distribution and quantification of immunoreactive orexin A in rat tissues , 1999, FEBS letters.

[26]  Emmanuel Mignot,et al.  The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene , 1999, Cell.

[27]  Jon T. Willie,et al.  Narcolepsy in orexin Knockout Mice Molecular Genetics of Sleep Regulation , 1999, Cell.

[28]  T. Sakurai,et al.  Structure and Function of Human Prepro-orexin Gene* , 1999, The Journal of Biological Chemistry.

[29]  T. Sakurai,et al.  Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[30]  D. Macneil,et al.  Distribution of orexin receptor mRNA in the rat brain , 1998, FEBS letters.

[31]  S. Carr,et al.  Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior , 1998, Cell.

[32]  F E Bloom,et al.  The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[33]  S. File.  Anxiolytic Action of a Neurokinin1 Receptor Antagonist in the Social Interaction Test , 1997, Pharmacology Biochemistry and Behavior.

[34]  G. Europe-Finner,et al.  Corticotrophin‐Releasing Hormone Receptor Type 1: Generation and Characterization of Polyclonal Antipeptide Antibodies and their Localization in Pituitary Cells and Cortical Neurones in vitro , 1996, Journal of neuroendocrinology.

[35]  R. Faull,et al.  The use of c-fos as a metabolic marker in neuronal pathway tracing , 1989, Journal of Neuroscience Methods.

[36]  K. Miczek.  A new test for aggression in rats without aversive stimulation: Differential effects of d-amphetamine and cocaine , 1979, Psychopharmacology.

[37]  C. Malbon,et al.  G-protein-coupled receptor-associated A-kinase anchoring proteins AKAP5 and AKAP12: differential trafficking and distribution. , 2009, Cellular signalling.

[38]  S. Carr,et al.  Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. , 1998, Cell.