Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations.

[1]  Linda Partridge,et al.  Unraveling the biological roles of reactive oxygen species. , 2011, Cell metabolism.

[2]  L. Partridge,et al.  Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix , 2011, Cell metabolism.

[3]  R. Mason,et al.  Studies on the photosensitized reduction of resorufin and implications for the detection of oxidative stress with Amplex Red. , 2011, Free radical biology & medicine.

[4]  D. Laskin,et al.  Application of the Amplex red/horseradish peroxidase assay to measure hydrogen peroxide generation by recombinant microsomal enzymes. , 2010, Free radical biology & medicine.

[5]  U. Brunk,et al.  What does the commonly used DCF test for oxidative stress really show? , 2010, The Biochemical journal.

[6]  B. Kalyanaraman,et al.  Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truth. , 2010, Free radical biology & medicine.

[7]  Bryan C Dickinson,et al.  A palette of fluorescent probes with varying emission colors for imaging hydrogen peroxide signaling in living cells. , 2010, Journal of the American Chemical Society.

[8]  J. Joseph,et al.  Peroxynitrite Is the Major Species Formed from Different Flux Ratios of Co-generated Nitric Oxide and Superoxide , 2010, The Journal of Biological Chemistry.

[9]  J. Joseph,et al.  Direct oxidation of boronates by peroxynitrite: mechanism and implications in fluorescence imaging of peroxynitrite. , 2009, Free radical biology & medicine.

[10]  N. Jen,et al.  A role for NADPH oxidase 4 in the activation of vascular endothelial cells by oxidized phospholipids. , 2009, Free radical biology & medicine.

[11]  L. Folkes,et al.  Kinetics of reaction of nitrogen dioxide with dihydrorhodamine and the reaction of the dihydrorhodamine radical with oxygen: implications for quantifying peroxynitrite formation in cells. , 2009, Archives of biochemistry and biophysics.

[12]  B. Kalyanaraman,et al.  "ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis"--a critical commentary. , 2008, Free radical biology & medicine.

[13]  P. Ping,et al.  Reactive Oxygen Species Production in Energized Cardiac Mitochondria During Hypoxia/Reoxygenation: Modulation by Nitric Oxide , 2008, Circulation research.

[14]  J. Hayashi,et al.  ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis , 2008, Science.

[15]  C. Winterbourn,et al.  Reconciling the chemistry and biology of reactive oxygen species. , 2008, Nature chemical biology.

[16]  Michael S Janes,et al.  The selective detection of mitochondrial superoxide by live cell imaging , 2008, Nature Protocols.

[17]  B. Kalyanaraman,et al.  Cytochrome c-mediated oxidation of hydroethidine and mito-hydroethidine in mitochondria: identification of homo- and heterodimers. , 2008, Free radical biology & medicine.

[18]  P. Wardman.  Methods to measure the reactivity of peroxynitrite-derived oxidants toward reduced fluoresceins and rhodamines. , 2008, Methods in enzymology.

[19]  M. Toledano,et al.  ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis , 2007, Nature Reviews Molecular Cell Biology.

[20]  D. Harrison,et al.  Measurement of reactive oxygen species in cardiovascular studies. , 2007, Hypertension.

[21]  B. Kalyanaraman,et al.  Detection of 2-hydroxyethidium in cellular systems: a unique marker product of superoxide and hydroethidine , 2007, Nature Protocols.

[22]  S. Lukyanov,et al.  Genetically encoded fluorescent indicator for intracellular hydrogen peroxide , 2006, Nature Methods.

[23]  M. Bonini,et al.  The oxidation of 2',7'-dichlorofluorescin to reactive oxygen species: a self-fulfilling prophesy? , 2006, Free radical biology & medicine.

[24]  Evan W. Miller,et al.  Boronate-based fluorescent probes for imaging cellular hydrogen peroxide. , 2005, Journal of the American Chemical Society.

[25]  A. Ramachandran,et al.  Oxidized LDL induces mitochondrially associated reactive oxygen/nitrogen species formation in endothelial cells. , 2005, American journal of physiology. Heart and circulatory physiology.

[26]  Hongtao Zhao,et al.  Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[27]  J. Joseph,et al.  Oxidant-induced iron signaling in Doxorubicin-mediated apoptosis. , 2004, Methods in enzymology.

[28]  A. Haas,et al.  Nitric oxide inhibits H2O2-induced transferrin receptor-dependent apoptosis in endothelial cells: Role of ubiquitin-proteasome pathway , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[29]  Hongtao Zhao,et al.  Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide. , 2003, Free radical biology & medicine.

[30]  J. Joseph,et al.  Oxidative Stress–Induced Iron Signaling Is Responsible for Peroxide-Dependent Oxidation of Dichlorodihydrofluorescein in Endothelial Cells: Role of Transferrin Receptor–Dependent Iron Uptake in Apoptosis , 2003, Circulation research.

[31]  Peter S. Kutchukian,et al.  Reaction of Superoxide and Nitric Oxide with Peroxynitrite , 2001, The Journal of Biological Chemistry.

[32]  P. Wardman,et al.  Cytochrome C is a potent catalyst of dichlorofluorescin oxidation: implications for the role of reactive oxygen species in apoptosis. , 2001, Biochemical and biophysical research communications.

[33]  D. Flaherty,et al.  Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: comparison with 2',7'-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2',7'-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123. , 1999, Free radical biology & medicine.

[34]  G. Buettner,et al.  Iron and dioxygen chemistry is an important route to initiation of biological free radical oxidations: an electron paramagnetic resonance spin trapping study. , 1999, Free radical biology & medicine.

[35]  H. Ischiropoulos,et al.  Oxidation of 2',7'-dichlorofluorescin by peroxynitrite. , 1997, Free radical research.

[36]  A. Carr,et al.  Assays using horseradish peroxidase and phenolic substrates require superoxide dismutase for accurate determination of hydrogen peroxide production by neutrophils. , 1994, Free radical biology & medicine.

[37]  H. Ischiropoulos,et al.  Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. , 1992, Chemical research in toxicology.

[38]  B. Halliwell,et al.  Free Radicals in Biology and Medicine , 1990 .

[39]  M. Seeds,et al.  Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation. , 1983, Journal of immunology.