Analysis of Persistent Organic Pollutants in Small Volumes of Human Plasma Technical Overview Introduction

Technological advancements in the fields of analytical chemistry and biochemistry have allowed for characterization of a broad range of chemical exposures that may be collectively involved with the onset of chronic illnesses. New developments in mass spectrometry (MS) have yielded measurements of thousands of chemicals in a single human specimen [1]. The comprehensive measurement and characterization of all chemical exposures in the human internal environment is a main objective of the exposome.