Methods for depicting overlap in overviews of systematic reviews: An introduction to static tabular and graphical displays.

OBJECTIVE To introduce potential static tabular and graphical techniques for visually presenting overlap between systematic reviews (SRs) included in overviews of systematic reviews (OoSRs). STUDY DESIGN AND SETTING The graphical approaches described include Venn and Euler diagrams, as well as matrix-based, node-link, and aggregation-based techniques. We used fundamental concepts of mathematics from set and network theory to develop our novel graphical approaches. The graphical displays were created using R. RESULTS Overview authors have the flexibility to choose from a variety of visualizations, depending on the characteristics of their study. If the OoSRs includes few SRs, a Venn or an Euler diagram can be used. In case of an OoSRs with more SRs, Upset plots, heatmaps and node-link graphs are more appropriate for visualizing overlapping SRs. Stacked bar plots constitute an aggregation-based technique of illustrating overlap. Strengths and limitations of each graphical approach are presented. CONCLUSION The degree of overlap should be explored for the entire study and for specific outcomes of interest. The proposed graphical techniques may assist methodologists and authors in identifying overlap, which in turn may improve validity and transparency in OoSRs. More research is needed to understand which technique would be most useful and easiest to understand.