Adaptive mutation F772S-enhanced p7-NS4A cooperation facilitates the assembly and release of hepatitis C virus and is associated with lipid droplet enlargement
暂无分享,去创建一个
Xiaobing Duan | J. Xia | Yuanping Zhou | Xi Liu | Yi-Ping Li | Zhanxue Xu | Muhammad Ikram Anwar | Yiyi Chen | G. Yuan | Ling Ma
[1] J. Xia,et al. Identification of nucleotides in the 5'UTR and amino acids substitutions that are essential for the infectivity of 5'UTR-NS5A recombinant of hepatitis C virus genotype 1b (strain Con1). , 2018, Virology.
[2] J. Bukh,et al. Efficient Hepatitis C Virus Genotype 1b Core-NS5A Recombinants Permit Efficacy Testing of Protease and NS5A Inhibitors , 2017, Antimicrobial Agents and Chemotherapy.
[3] H. Breitinger,et al. The p7 viroporin of the hepatitis C virus contributes to liver inflammation by stimulating production of Interleukin-1β. , 2017, Biochimica et biophysica acta. Molecular basis of disease.
[4] G. Long,et al. Visualizing the Essential Role of Complete Virion Assembly Machinery in Efficient Hepatitis C Virus Cell-to-Cell Transmission by a Viral Infection-Activated Split-Intein-Mediated Reporter System , 2016, Journal of Virology.
[5] J. Bukh,et al. Robust HCV Genotype 3a Infectious Cell Culture System Permits Identification of Escape Variants With Resistance to Sofosbuvir. , 2016, Gastroenterology.
[6] G. Waris,et al. The Hepatitis C Virus-induced NLRP3 Inflammasome Activates the Sterol Regulatory Element-binding Protein (SREBP) and Regulates Lipid Metabolism* , 2015, The Journal of Biological Chemistry.
[7] Christopher T. Jones,et al. The N-terminal Helical Region of the Hepatitis C Virus p7 Ion Channel Protein Is Critical for Infectious Virus Production , 2015, PLoS pathogens.
[8] J. Pawlotsky. Therapy: Avoiding treatment failures associated with HCV resistance , 2015, Nature Reviews Gastroenterology &Hepatology.
[9] Mounavya Aligeti,et al. Cooperation between the Hepatitis C Virus p7 and NS5B Proteins Enhances Virion Infectivity , 2015, Journal of Virology.
[10] J. Bukh,et al. Adaptive Mutations Enhance Assembly and Cell-to-Cell Transmission of a High-Titer Hepatitis C Virus Genotype 5a Core-NS2 JFH1-Based Recombinant , 2015, Journal of Virology.
[11] R. Bartenschlager,et al. Hepatitis C Virus RNA Replication and Assembly: Living on the Fat of the Land , 2014, Cell Host & Microbe.
[12] J. Bukh,et al. Efficient Infectious Cell Culture Systems of the Hepatitis C Virus (HCV) Prototype Strains HCV-1 and H77 , 2014, Journal of Virology.
[13] J. Bukh,et al. Differential sensitivity of 5'UTR-NS5A recombinants of hepatitis C virus genotypes 1-6 to protease and NS5A inhibitors. , 2014, Gastroenterology.
[14] J. Bukh,et al. Highly efficient infectious cell culture of three hepatitis C virus genotype 2b strains and sensitivity to lead protease, nonstructural protein 5A, and polymerase inhibitors , 2014, Hepatology.
[15] Jin Zhong,et al. A Novel Strategy To Develop a Robust Infectious Hepatitis C Virus Cell Culture System Directly from a Clinical Isolate , 2013, Journal of Virology.
[16] Andrew S. Kohlway,et al. Hepatitis C Virus RNA Replication and Virus Particle Assembly Require Specific Dimerization of the NS4A Protein Transmembrane Domain , 2013, Journal of Virology.
[17] Matthew J. Bentham,et al. Mutations in hepatitis C virus p7 reduce both the egress and infectivity of assembled particles via impaired proton channel function. , 2013, The Journal of general virology.
[18] J. Bukh,et al. Adapted J6/JFH1-Based Hepatitis C Virus Recombinants with Genotype-Specific NS4A Show Similar Efficacies against Lead Protease Inhibitors, Alpha Interferon, and a Putative NS4A Inhibitor , 2013, Antimicrobial Agents and Chemotherapy.
[19] David L. Thomas,et al. Global control of hepatitis C: where challenge meets opportunity , 2013, Nature Medicine.
[20] C. Rice,et al. Understanding the hepatitis C virus life cycle paves the way for highly effective therapies , 2013, Nature Medicine.
[21] L. Kaderali,et al. Hepatitis C Virus p7 is Critical for Capsid Assembly and Envelopment , 2013, PLoS pathogens.
[22] J. Pawlotsky,et al. The Cobas AmpliPrep/Cobas TaqMan HCV Test, Version 2.0, Real-Time PCR Assay Accurately Quantifies Hepatitis C Virus Genotype 4 RNA , 2013, Journal of Clinical Microbiology.
[23] P. Roingeard,et al. Subcellular Localization and Function of an Epitope-Tagged p7 Viroporin in Hepatitis C Virus-Producing Cells , 2012, Journal of Virology.
[24] R. Purcell,et al. Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system , 2012, Proceedings of the National Academy of Sciences.
[25] R. Purcell,et al. Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains , 2012, Proceedings of the National Academy of Sciences.
[26] H. Netter,et al. Hepatitis C Virus Nonstructural Protein 5B Is Involved in Virus Morphogenesis , 2012, Journal of Virology.
[27] M. Gale,et al. Control of Innate Immune Signaling and Membrane Targeting by the Hepatitis C Virus NS3/4A Protease Are Governed by the NS3 Helix α0 , 2012, Journal of Virology.
[28] R. Bartenschlager,et al. A Concerted Action of Hepatitis C Virus P7 and Nonstructural Protein 2 Regulates Core Localization at the Endoplasmic Reticulum and Virus Assembly , 2011, PLoS pathogens.
[29] J. Bukh,et al. Development and Application of Hepatitis C Reporter Viruses with Genotype 1 to 7 Core-Nonstructural Protein 2 (NS2) Expressing Fluorescent Proteins or Luciferase in Modified JFH1 NS5A , 2011, Journal of Virology.
[30] J. Bukh,et al. MicroRNA-122 antagonism against hepatitis C virus genotypes 1–6 and reduced efficacy by host RNA insertion or mutations in the HCV 5′ UTR , 2011, Proceedings of the National Academy of Sciences.
[31] B. Lindenbach,et al. Hepatitis C Virus NS2 Coordinates Virus Particle Assembly through Physical Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes , 2010, Journal of Virology.
[32] R. Dwek,et al. The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy , 2009, Proceedings of the National Academy of Sciences.
[33] B. Lindenbach,et al. Hepatitis C Virus NS2 Protein Contributes to Virus Particle Assembly via Opposing Epistatic Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes , 2009, Journal of Virology.
[34] S. Emerson,et al. Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus , 2008, Proceedings of the National Academy of Sciences.
[35] J. Bukh,et al. Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses. , 2007, Gastroenterology.
[36] R. Bartenschlager,et al. Cell Culture Adaptation of Hepatitis C Virus and In Vivo Viability of an Adapted Variant , 2007, Journal of Virology.
[37] R. Bartenschlager,et al. The lipid droplet is an important organelle for hepatitis C virus production , 2007, Nature Cell Biology.
[38] Christopher T. Jones,et al. Alanine Scanning of the Hepatitis C Virus Core Protein Reveals Numerous Residues Essential for Production of Infectious Virus , 2007, Journal of Virology.
[39] F. Penin,et al. Hepatitis C Virus p7 Protein Is Crucial for Assembly and Release of Infectious Virions , 2007, PLoS pathogens.
[40] C. Rice,et al. The C Terminus of Hepatitis C Virus NS4A Encodes an Electrostatic Switch That Regulates NS5A Hyperphosphorylation and Viral Replication , 2007, Journal of Virology.
[41] L. Babiuk,et al. Up-regulation of fatty acid synthase promoter by hepatitis C virus core protein: genotype-3a core has a stronger effect than genotype-1b core. , 2007, Journal of hepatology.
[42] Darius Moradpour,et al. Replication of hepatitis C virus , 2007, Nature Reviews Microbiology.
[43] Christopher T. Jones,et al. Hepatitis C Virus p7 and NS2 Proteins Are Essential for Production of Infectious Virus , 2007, Journal of Virology.
[44] Christophe Combet,et al. A comprehensive system for consistent numbering of HCV sequences, proteins and epitopes , 2006, Hepatology.
[45] S. Lemon,et al. Compensatory Mutations in E1, p7, NS2, and NS3 Enhance Yields of Cell Culture-Infectious Intergenotypic Chimeric Hepatitis C Virus , 2006, Journal of Virology.
[46] H. Wedemeyer,et al. Treating viral hepatitis C: efficacy, side effects, and complications , 2006, Gut.
[47] Qiang Sun,et al. Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKε Molecular Complex from the Mitochondrial Outer Membrane by Hepatitis C Virus NS3-4A Proteolytic Cleavage , 2006, Journal of Virology.
[48] Zhijian J. Chen,et al. Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[49] Ralf Bartenschlager,et al. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus , 2005, Nature.
[50] Toshiaki Maruyama,et al. Complete Replication of Hepatitis C Virus in Cell Culture , 2005, Science.
[51] R. Bartenschlager,et al. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome , 2005, Nature Medicine.
[52] D. Burton,et al. Robust hepatitis C virus infection in vitro. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[53] S. Emerson,et al. The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[54] P. Maruvada,et al. Role of the Asialoglycoprotein Receptor in Binding and Entry of Hepatitis C Virus Structural Proteins in Cultured Human Hepatocytes , 2003, Journal of Virology.
[55] J. Hoofnagle. Course and outcome of hepatitis C , 2002, Hepatology.
[56] J. Silver,et al. Replication of Subgenomic Hepatitis C Virus Rnas in a Hepatoma Cell Line , 1999 .
[57] C. Rice,et al. Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C termini , 1994, Journal of virology.