Development of a handheld diffuse optical breast cancer assessment probe

Diffuse Optical Spectroscopy (DOS) is a promising non-invasive and non-ionizing technique for breast anomaly detection. In this study, we have developed a new handheld DOS probe to measure optical properties of breast tissue. In the proposed probe, the breast tissue is illuminated with four near infrared (NIR) wavelengths light emitting diodes (LED), which are encapsulated in a package (eLEDs), and two PIN photodiodes measure the intensity of the scattered photons at two different locations. The proposed technique of using eLEDs is introduced, in order to have a multi-wavelength pointed-beam illumination source instead of using the laser-coupled fiber-optic technique, which increases the complexity, size, and cost of the probe. Despite the fact that the proposed technique miniaturizes the probe and reduces the complexity of the DOS, the study proves that it is accurate and reliable in measuring optical properties of the tissue. The measurements are performed at the rate of 10Hz which is suitable for dynam...

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