Three-Dimensional Shape-Motion Analysis of the Left Anterior Descending Coronary Artery in EBCT Images

In this paper, we present a physics-based deformable model framework for the quantification of shape and motion parameters of the Left Anterior Descending (LAD) coronary artery in the heart’s local frame of reference. We define the long-axis of the heart as the local frame of reference. The shape of the LAD is modeled as a parametric curved axis with Frenet-Serret frame. The motion of the LAD (due to heart motion) is modeled as a composite of primitive shape-motion components: 1) longitudinal elongation, 2) radial displacement, and 3) twist with respect to the heart’s local frame of reference. The three-dimensional shape-motion components are parameterized along the LAD’s length. Results from simulated data and three asymptomatic subjects’ Electron Beam Computed Tomography (EBCT) data are in agreement with the expected physiological trends.

[1]  Jinah Park,et al.  Deformable models with parameter functions for cardiac motion analysis from tagged MRI data , 1996, IEEE Trans. Medical Imaging.

[2]  Alejandro F. Frangi,et al.  Three-dimensional modeling for functional analysis of cardiac images, a review , 2001, IEEE Transactions on Medical Imaging.

[3]  John D. Carroll,et al.  Kinematic and deformation analysis of 4-D coronary arterial trees reconstructed from cine angiograms , 2003, IEEE Transactions on Medical Imaging.

[4]  Phillips Re,et al.  The role of material surface chemistry in implant device calcification: a hypothesis. , 1995 .

[5]  L. D. R. Smith,et al.  Working towards the automatic detection of blood vessels in X-ray angiograms , 1987, Pattern Recognit. Lett..

[6]  Neil B. Ingels,et al.  Torsional Deformation of the Left Ventricular Midwall in Human Hearts With Intramyocardial Markers: Regional Heterogeneity and Sensitivity to the Inotropic Effects of Abrupt Rate Changes , 1988, Circulation research.

[7]  John D Carroll,et al.  Four‐dimensional analysis of cyclic changes in coronary artery shape , 2002, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[8]  Milan Sonka,et al.  A quantitative study of coronary vasculature in four dimensions , 2000, Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Cat. No.00CH37143).

[9]  Dimitris N. Metaxas,et al.  Dynamic 3D models with local and global deformations: deformable superquadrics , 1990, [1990] Proceedings Third International Conference on Computer Vision.

[10]  S A MacKay,et al.  Methods for evaluating cardiac wall motion in three dimensions using bifurcation points of the coronary arterial tree. , 1983, Investigative radiology.

[11]  D C Miller,et al.  Torsional deformation of the left ventricle. , 1995, The Journal of heart valve disease.

[12]  Dimitris N. Metaxas,et al.  Motion Analysis of the Right Ventricle From MRI Images , 1998, MICCAI.

[13]  Morton H. Friedman,et al.  Quantification of 3-D coronary arterial motion using clinical biplane cineangiograms , 2000, The International Journal of Cardiac Imaging.

[14]  William M. Wells,et al.  Medical Image Computing and Computer-Assisted Intervention — MICCAI’98 , 1998, Lecture Notes in Computer Science.

[15]  Alejandro F. Frangi,et al.  Quantitative analysis of vascular morphology from 3D MR angiograms: In vitro and in vivo results , 2001, Magnetic resonance in medicine.

[16]  Ioannis A. Kakadiaris,et al.  Elastically Adaptive Deformable Models , 1996, ECCV.

[17]  Ioannis A. Kakadiaris,et al.  Estimating the Motion of the LAD: A Simulation-Based Study , 2001, MICCAI.

[18]  Dimitris N. Metaxas,et al.  Shape and Nonrigid Motion Estimation Through Physics-Based Synthesis , 1993, IEEE Trans. Pattern Anal. Mach. Intell..

[19]  H D McIntosh,et al.  Assessment of regional myocardial performance from biplane coronary cineangiograms. , 1971, The American journal of cardiology.

[20]  Wiro J. Niessen,et al.  Medical Image Computing and Computer-Assisted Intervention – MICCAI 2001 , 2001, Lecture Notes in Computer Science.