Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.
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Nick C. Fox | Pietro Pietrini | Alexander Gerhard | Jason D. Warren | Ian G. McKeith | Adrian Danek | Timothy D. Griffiths | Luigi Ferrucci | Dimitrios Kapogiannis | Bruce L. Miller | Murray Grossman | Martin N. Rossor | James B. Rowe | Nick C Fox | William W. Seeley | Jordan Grafman | Jonathan D. Rohrer | Gianluigi Forloni | Ronald C. Petersen | John Q. Trojanowski | Stefano F. Cappa | Philip Scheltens | Olivier Piguet | Janine Diehl-Schmid | Carol Dobson-Stone | Amalia C. Bruni | Patrizia Rizzu | Yolande A. L. Pijnenburg | Sandro Sorbi | Daniel H. Geschwind | Raffaele Ferrari | Bradley F. Boeve | Barbara Borroni | Alessandro Padovani | Eric M. Wassermann | John Hardy | Stephen J. Haggarty | Gilles Gasparoni | Peter R. Schofield | Karin Nilsson | Howard Rosen | Giuliano Binetti | Giancarlo Logroscino | Alberto Lleó | Julie S. Snowden | Peter Heutink | Alan J. Thomas | Glenda M. Halliday | Arjun Sarkar | Dennis W. Dickson | Nigel J. Cairns | David Knopman | Allan I. Levey | Joseph E. Parisi | Florence Pasquier | Didier Hannequin | Jørgen E. Nielsen | Adaikalavan Ramasamy | John R. Hodges | Annibale A. Puca | Robert Perneczky | Neill R. Graff-Radford | Bernd Ibach | Innocenzo Rainero | Alfredo Postiglione | Graziella Milan | Huw R. Morris | Luisa Benussi | Roberta Ghidoni | Ekaterina Rogaeva | Andrew B. Singleton | Elise G. P. Dopper | John C. van Swieten | Keith A. Josephs | Marc Cruts | Christine Van Broeckhoven | John Collinge | Cristina Razquin | Pau Pastor | Panagiotis Alexopoulos | Atik Baborie | Giorgio Giaccone | Fabrizio Tagliavini | David M. A. Mann | James J. Lah | Daniela Galimberti | Caroline Graff | Matthias Riemenschneider | Sara Rollinson | Manuel Mayhaus | Vivek Swarup | D. Hernandez | M. Nalls | A. Singleton | L. Ferrucci | A. Ramasamy | E. Haan | D. Geschwind | S. Haggarty | P. Pietrini | J. Grafman | R. Petersen | J. Trojanowski | P. Scheltens | J. Hardy | S. Cappa | A. Levey | N. Seyfried | J. Hodges | M. Mayhaus | T. Griffiths | B. Boeve | D. Knopman | I. McKeith | J. Attems | C. Morris | J. Rowe | M. Rossor | F. Pasquier | M. Grossman | D. Dickson | J. Parisi | N. Cairns | P. Schofield | D. Knopman | M. Franceschi | C. van Broeckhoven | V. Novelli | W. Seeley | A. Kurz | A. Danek | Y. Pijnenburg | D. Mann | S. Mead | J. Collinge | C. Cruchaga | E. Wassermann | Carlos Cruchaga | S. Rollinson | H. Rosen | G. Logroscino | R. Perneczky | J. Diehl-Schmid | S. Sorbi | B. Nacmias | D. Galimberti | D. Hannequin | G. Halliday | W. Brooks | A. Karydas | J. Rohrer | C. Nilsson | P. Heutink | J. Lah | J. Kwok | C. Fenoglio | G. Forloni | E. Scarpini | M. Cruts | E. Huey | J. Snowden | A. Brice | M. Riemenschneider | J. Warren | A. Ruiz | V. Deramecourt | E. Rogaeva | P. George-Hyslop | J. Clarimón | A. Lleó | S. Pichler | C. Razquín | P. Pástor | M. Boada | C. Graff | G. Hsiung | M. Spillantini | N. Graff-Radford | A. Richardson | G. Binetti | O. Piguet | I. Mackenzie | C. Cupidi | J. V. van Swieten | B. Borroni | F. Tagliavini | H. Toyoshiba | A. Padovani | A. Puca | V. Swarup | H. Morris | C. Dobson-Stone | E. Jaros | P. Rizzu | L. Pinessi | R. Blesa | M. Kristiansen | A. Bruni | K. Hirai | M. Baker | S. Pickering-Brown | I. Hernández | D. Kapogiannis | P. Alexopoulos | L. Benussi | R. Ghidoni | I. Rainero | G. Gasparoni | M. Anfossi | S. Bagnoli | L. Bernardi | Huei-Hsin Chiang | M. E. Conidi | F. Frangipane | M. Gallo | R. Maletta | G. Milan | P. Momeni | I. Piaceri | G. Rossi | E. Rubino | M. Serpente | N. Smirne | V. V. Van Deerlin | J. van der Zee | M. L. Waldö | R. Ferrari | Chialin Cheng | F. Hinz | Jessica E Rexach | K. Noguchi | A. Oda | Arjun Sarkar | V. Golfier | M. Vercelletto | D. Albani | R. Capozzo | H. Seelaar | E. Dopper | K. Josephs | J. Schlachetzki | A. Gerhard | H. Rosen | T. Lebouvier | A. Baborie | J. Hardy | J. Uphill | S. Ortega-Cubero | J. Nielsen | B. Ibach | E. Thompson | Jessica E. Rexach | Matt Baker | Rosa Rademakers | Dena G. Hernandez | Michael A. Nalls | Ian R. A. Mackenzie | Stuart Pickering-Brown | Evelyn Jaros | Alexander Kurz | Massimo Franceschi | Alexis Brice | L. Hjermind | Sara Ortega-Cubero | Carlos Cruchaga | James Uphill | Elio Scarpini | Isabel Hernández | Vincent Deramecourt | Chiara Cupidi | Simon Mead | Benedetta Nacmias | Maura Gallo | Johannes C. M. Schlachetzki | Vivianna M. Van Deerlin | Mercè Boada | Silvia Bagnoli | Irene Piaceri | Hiroyoshi Toyoshiba | John B. J. Kwok | E. Haan | Nicholas T. Seyfried | Maria Grazia Spillantini | Lauren Bartley | Elizabeth Thompson | Agustín Ruiz | Chiara Fenoglio | Maria Serpente | Jordi Clarimón | Rafael Blesa | Maria Landqvist Waldö | Christer Nilsson | Johannes Attems | Elena Alonso | Elisa Rubino | Lorenzo Pinessi | Giacomina Rossi | Véronique Golfier | Martine Vercelletto | Sabrina Pichler | Anna Richardson | Raffaele Maletta | Francesca Frangipane | Livia Bernardi | Maria Anfossi | Maria Elena Conidi | Nicoletta Smirne | Harro Seelaar | Rosa Capozzo | Valeria Novelli | Paolo Sorrentino | Mark Kristiansen | Huei-Hsin Chiang | Adeline Rollin | Parastoo Momeni | Flora I. Hinz | Julie van der Zee | L. Bartley | G. Giaccone | Edward D. Huey | A. Postiglione | Anna M. Karydas | Eric Haan | Diego Albani | Ging-Yuek R. Hsiung | A. Rollin | Thibaud Lebouvier | Chialin Cheng | Lena E. Hjermind | Michael C. Tierney | Keisuke Hirai | Christopher M. Morris | Ken-ichi Noguchi | Akira Oda | Raffaele Jonathan D. Adaikalavan John Dena G. Michael A. An Ferrari Rohrer Ramasamy Hardy Hernandez | William S. Brooks | Peter St. George-Hyslop | Isabelle Leber | Shinichi Kondou | M. Tierney | K. Nilsson | P. Sorrentino | E. Alonso | I. Leber | J. Rowe | M. Baker | Karin Nilsson | Ronald C. Petersen | R. Rademakers | B. Miller | Shinichi Kondou | F. Pasquier | J. E. Nielsen | Daniel H. Geschwind | Bruce L. Miller | V. V. van Deerlin | M. Franceschi | Raffaele Jonathan D. Adaikalavan John Dena G. Michael A. An Ferrari Rohrer Ramasamy Hardy Hernandez | D. Mann | A. J. Thomas | P. Sorrentino | B. Miller | H. Chiang | D. Knopman | M. Grossman | J. Hardy | Hiroyoshi Toyoshiba | P. Pastor
[1] S. Horvath,et al. Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap , 2016, Science.
[2] D. Geschwind,et al. Molecular Genetics of Neurodegenerative Dementias. , 2017, Cold Spring Harbor perspectives in biology.
[3] Madhav Thambisetty,et al. A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease. , 2017, Cell systems.
[4] S. Haggarty,et al. Highly Expandable Human iPS Cell–Derived Neural Progenitor Cells (NPC) and Neurons for Central Nervous System Disease Modeling and High‐Throughput Screening , 2017, Current protocols in human genetics.
[5] Luis de la Torre Ubieta,et al. Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism , 2016, Nature.
[6] James A. Eddy,et al. Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases , 2016, Scientific Data.
[7] E. Mandelkow,et al. MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations , 2016, Stem cell reports.
[8] Benjamin A. Logsdon,et al. Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia , 2016, Nature Neuroscience.
[9] Michelle K. Cahill,et al. Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation , 2016, Cell.
[10] Benjamin E. L. Lauffer,et al. Untangling the brain's neuroinflammatory and neurodegenerative transcriptional responses , 2016, Nature Communications.
[11] J. Hardy,et al. Catastrophic cliffs: a partial suggestion for selective vulnerability in neurodegenerative diseases. , 2016, Biochemical Society transactions.
[12] A. Kaddoumi,et al. Effect of mouse strain as a background for Alzheimer's disease models on the clearance of amyloid-β. , 2016, Journal of systems and integrative neuroscience.
[13] S. Maeda,et al. Expression of A152T human tau causes age‐dependent neuronal dysfunction and loss in transgenic mice , 2016, EMBO reports.
[14] Daniel J. Gaffney,et al. A survey of best practices for RNA-seq data analysis , 2016, Genome Biology.
[15] Fei Liu,et al. Tau and neurodegenerative disease: the story so far , 2016, Nature Reviews Neurology.
[16] Shrikant S. Mantri,et al. Targeting MicroRNAs in Prevention and Treatment of Neurodegenerative Disorders , 2015, Drug development research.
[17] Allan R. Jones,et al. Canonical Genetic Signatures of the Adult Human Brain , 2015, Nature Neuroscience.
[18] Christian A. Ross,et al. Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS , 2015, Nature Neuroscience.
[19] Daniel H. Geschwind,et al. Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders , 2015, Nature Reviews Genetics.
[20] K. Ashe,et al. Morris Water Maze Test: Optimization for Mouse Strain and Testing Environment. , 2015, Journal of visualized experiments : JoVE.
[21] E. Stern,et al. Pathological Tau Disrupts Ongoing Network Activity , 2015, Neuron.
[22] B. Miller,et al. Frontotemporal dementia: a bridge between dementia and neuromuscular disease , 2015, Annals of the New York Academy of Sciences.
[23] F. Edwards,et al. A genome-wide gene-expression analysis and database in transgenic mice during development of amyloid or tau pathology. , 2015, Cell reports.
[24] G. Kovacs,et al. Invited review: Neuropathology of tauopathies: principles and practice , 2015, Neuropathology and applied neurobiology.
[25] J. Gallacher,et al. Convergent genetic and expression data implicate immunity in Alzheimer's disease , 2014, Alzheimer's & Dementia.
[26] Paul Theodor Pyl,et al. HTSeq—a Python framework to work with high-throughput sequencing data , 2014, bioRxiv.
[27] Reisa A. Sperling,et al. Alzheimer's disease , 2015, Nature Reviews Disease Primers.
[28] W. Held,et al. Malt1 protease inactivation efficiently dampens immune responses but causes spontaneous autoimmunity , 2014, The EMBO journal.
[29] W. Huber,et al. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.
[30] T. Maniatis,et al. An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex , 2014, The Journal of Neuroscience.
[31] J. Corradi,et al. Tau Overexpression Impacts a Neuroinflammation Gene Expression Network Perturbed in Alzheimer’s Disease , 2014, PloS one.
[32] Alexander Gerhard,et al. Frontotemporal dementia and its subtypes: a genome-wide association study , 2014, The Lancet Neurology.
[33] Xia Yang,et al. Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases , 2014 .
[34] Marco Y. Hein,et al. Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ * , 2014, Molecular & Cellular Proteomics.
[35] F. Schmitt,et al. Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models , 2014, Front. Genet..
[36] D. Rujescu,et al. A Conserved BDNF, Glutamate- and GABA-Enriched Gene Module Related to Human Depression Identified by Coexpression Meta-Analysis and DNA Variant Genome-Wide Association Studies , 2014, PloS one.
[37] Yoshio Matsumoto,et al. Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice , 2014, Neuroscience Research.
[38] Nick C Fox,et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease , 2013, Nature Genetics.
[39] S. Horvath,et al. Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism , 2013, Cell.
[40] P. Gaffney,et al. Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren’s syndrome , 2013, Nature Genetics.
[41] S. Horvath,et al. Genes and pathways underlying regional and cell type changes in Alzheimer's disease , 2013, Genome Medicine.
[42] S. Kauppinen,et al. Treatment of HCV infection by targeting microRNA. , 2013, The New England journal of medicine.
[43] L. Tran,et al. Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease , 2013, Cell.
[44] K. Mullane,et al. Alzheimer's therapeutics: continued clinical failures question the validity of the amyloid hypothesis-but what lies beyond? , 2013, Biochemical pharmacology.
[45] Thomas R. Gingeras,et al. STAR: ultrafast universal RNA-seq aligner , 2013, Bioinform..
[46] Cole Trapnell,et al. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions , 2013, Genome Biology.
[47] Frank M LaFerla,et al. Animal models of Alzheimer disease. , 2012, Cold Spring Harbor perspectives in medicine.
[48] Robert V Farese,et al. Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects. , 2012, Cell reports.
[49] V. Berezin,et al. Neuroligin‐1 induces neurite outgrowth through interaction with neurexin‐1β and activation of fibroblast growth factor receptor‐1 , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[50] Chris T. A. Evelo,et al. Bioinformatics Applications Note Databases and Ontologies Go-elite: a Flexible Solution for Pathway and Ontology Over-representation , 2022 .
[51] Stefan L Ameres,et al. Long-term, efficient inhibition of microRNA function in mice using rAAV vectors , 2012, Nature Methods.
[52] K. Hansen,et al. Removing technical variability in RNA-seq data using conditional quantile normalization , 2012, Biostatistics.
[53] Sebastian D. Mackowiak,et al. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades , 2011, Nucleic acids research.
[54] Sandrine Dudoit,et al. GC-Content Normalization for RNA-Seq Data , 2011, BMC Bioinformatics.
[55] R. Faull,et al. Population-specific expression analysis (PSEA) reveals molecular changes in diseased brain , 2011, Nature Methods.
[56] Andrew J. Lees,et al. Identification of common variants influencing risk of the tauopathy Progressive Supranuclear Palsy , 2011, Nature Genetics.
[57] Daniel H. Geschwind,et al. The Human Brain in a Dish: The Promise of iPSC-Derived Neurons , 2011, Cell.
[58] S. Horvath,et al. Transcriptomic Analysis of Autistic Brain Reveals Convergent Molecular Pathology , 2011, Nature.
[59] M. Daly,et al. Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology , 2011, PLoS genetics.
[60] Rui Luo,et al. Is My Network Module Preserved and Reproducible? , 2011, PLoS Comput. Biol..
[61] D. Selkoe. Alzheimer's disease. , 2011, Cold Spring Harbor perspectives in biology.
[62] S. Horvath,et al. Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways , 2010, Proceedings of the National Academy of Sciences.
[63] Douglas D Young,et al. Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma. , 2010, Journal of the American Chemical Society.
[64] Mark D. Robinson,et al. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data , 2009, Bioinform..
[65] Gonçalo R. Abecasis,et al. The Sequence Alignment/Map format and SAMtools , 2009, Bioinform..
[66] Steve Horvath,et al. WGCNA: an R package for weighted correlation network analysis , 2008, BMC Bioinformatics.
[67] L. Lim,et al. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. , 2007, Molecular cell.
[68] Pall I. Olason,et al. A human phenome-interactome network of protein complexes implicated in genetic disorders , 2007, Nature Biotechnology.
[69] Bin Zhang,et al. Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model , 2007, Neuron.
[70] Léon Personnaz,et al. Enrichment or depletion of a GO category within a class of genes: which test? , 2007, Bioinform..
[71] Steve Horvath,et al. Network neighborhood analysis with the multi-node topological overlap measure , 2007, Bioinform..
[72] Paul A Clemons,et al. The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease , 2006, Science.
[73] D. Geschwind,et al. A Genomic Screen for Modifiers of Tauopathy Identifies Puromycin-Sensitive Aminopeptidase as an Inhibitor of Tau-Induced Neurodegeneration , 2006, Neuron.
[74] Mike Tyers,et al. BioGRID: a general repository for interaction datasets , 2005, Nucleic Acids Res..
[75] Gábor Csárdi,et al. The igraph software package for complex network research , 2006 .
[76] Thomas Ragg,et al. The RIN: an RNA integrity number for assigning integrity values to RNA measurements , 2006, BMC Molecular Biology.
[77] S. Horvath,et al. Statistical Applications in Genetics and Molecular Biology , 2011 .
[78] D. Hume,et al. Syntaxin 6 and Vti1b Form a Novel SNARE Complex, Which Is Up-regulated in Activated Macrophages to Facilitate Exocytosis of Tumor Necrosis Factor-α* , 2005, Journal of Biological Chemistry.
[79] K. Reymann,et al. Neurogranin/RC3 Enhances Long-Term Potentiation and Learning by Promoting Calcium-Mediated Signaling , 2004, The Journal of Neuroscience.
[80] H. Braak,et al. Neuropathological stageing of Alzheimer-related changes , 2004, Acta Neuropathologica.
[81] S. Turner,et al. Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695* , 2001, The Journal of Biological Chemistry.
[82] D. Dickson. The story so far… , 2000, Nature.
[83] M. Goedert,et al. Tau protein pathology in neurodegenerative diseases , 1998, Trends in Neurosciences.
[84] Y. Benjamini,et al. Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .