Optofluidic sieving with flow-through plasmonic nanohole arrays

Sieving potential and resulting improved analyte collection in flow-through nanohole array sensors is compared to planar SPR sensing. At typical flow rates, full analyte collection, reaction limited transport and attomolar critical concentrations can be achieved.

[1]  David Sinton,et al.  Nanoholes as nanochannels: flow-through plasmonic sensing. , 2009, Analytical chemistry.

[2]  W. Barnes,et al.  Surface plasmon subwavelength optics , 2003, Nature.

[3]  K. Kavanagh,et al.  A new generation of sensors based on extraordinary optical transmission. , 2008, Accounts of chemical research.

[4]  David Sinton,et al.  Attomolar protein detection using in-hole surface plasmon resonance. , 2009, Journal of the American Chemical Society.

[5]  Robert J. Messinger,et al.  Making it stick: convection, reaction and diffusion in surface-based biosensors , 2008, Nature Biotechnology.

[6]  R. Rosenfeld.  Nature , 2009, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[7]  Y. Fainman,et al.  High-resolution surface plasmon resonance sensor based on linewidth-optimized nanohole array transmittance. , 2006, Optics letters.

[8]  T. S. West.  Analytical Chemistry , 1969, Nature.

[9]  Kendall N Houk,et al.  Accounts of Chemical Research. , 2008, Accounts of chemical research.