Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing
暂无分享,去创建一个
B. Fakler | M. Staufenbiel | Txomin Lalanne | M. Gassmann | B. Bettler | R. Turecek | W. Bildl | Michal Stawarski | Adi Raveh | D. Bentrop | Valérie Besseyrias | Simon P Früh | T. Fritzius | A. Schneider | Myeongjeong Choo | Pascal D. Rem | M. Dinamarca | Jochen Schwenk | Simon P. Früh | Thorsten Fritzius | P. D. Rem
[1] S. Kins,et al. Trafficking in Alzheimer’s Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin , 2018, Molecular Neurobiology.
[2] Jason R Pugh,et al. Activity‐dependent plasticity of presynaptic GABAB receptors at parallel fiber synapses , 2018, Synapse.
[3] S. Kins,et al. Trafficking in Alzheimer’s Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin , 2017, Molecular Neurobiology.
[4] A. Frangaj,et al. Structural biology of GABAB receptor , 2017, Neuropharmacology.
[5] B. Fakler,et al. AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability , 2017, Nature Communications.
[6] C. Akerman,et al. Neuronal Chloride Regulation via KCC2 Is Modulated through a GABAB Receptor Protein Complex , 2017, The Journal of Neuroscience.
[7] M. Korte,et al. Not just amyloid: physiological functions of the amyloid precursor protein family , 2017, Nature Reviews Neuroscience.
[8] T. Tomita,et al. Memantine reduces the production of amyloid‐&bgr; peptides through modulation of amyloid precursor protein trafficking , 2017, European journal of pharmacology.
[9] R. J. Mather,et al. Deficits in the activity of presynaptic γ-aminobutyric acid type B receptors contribute to altered neuronal excitability in fragile X syndrome , 2017, The Journal of Biological Chemistry.
[10] Hui Zheng,et al. APP modulates KCC2 expression and function in hippocampal GABAergic inhibition , 2017, eLife.
[11] Bo Li,et al. Prefrontal Cortical GABAergic Dysfunction Contributes to Aberrant UP-State Duration in APP Knockout Mice , 2016, Cerebral cortex.
[12] A. Triller,et al. Phospho-dependent Accumulation of GABABRs at Presynaptic Terminals after NMDAR Activation , 2016, Cell reports.
[13] S. Goerdt,et al. Leda-1/Pianp is targeted to the basolateral plasma membrane by a distinct intracellular juxtamembrane region and modulates barrier properties and E-Cadherin processing. , 2016, Biochemical and biophysical research communications.
[14] Regina Berretta,et al. Identification of Differentially Expressed Genes through Integrated Study of Alzheimer’s Disease Affected Brain Regions , 2016, PloS one.
[15] J. Hardy,et al. The amyloid hypothesis of Alzheimer's disease at 25 years , 2016, EMBO molecular medicine.
[16] E. Pérez-Garci,et al. Modular composition and dynamics of native GABAB receptors identified by high-resolution proteomics , 2015, Nature Neuroscience.
[17] S. Wagner,et al. Visualization of APP and BACE-1 approximation in neurons: new insights into the amyloidogenic pathway , 2015, Nature neuroscience.
[18] Mazen A. Kheirbek,et al. Loss of Striatonigral GABAergic Presynaptic Inhibition Enables Motor Sensitization in Parkinsonian Mice , 2015, Neuron.
[19] R. D'Hooge,et al. Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to SynapticDeficits in Fragile X Syndrome , 2015, Neuron.
[20] A. Nairn,et al. Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport , 2014, Molecular biology of the cell.
[21] G. Dolios,et al. Differential Release of β-Amyloid from Dendrite- Versus Axon-Targeted APP , 2014, The Journal of Neuroscience.
[22] Yong Jeong,et al. GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease , 2014, Nature Medicine.
[23] E. Isacoff,et al. APP homodimers transduce an amyloid-β-mediated increase in release probability at excitatory synapses. , 2014, Cell reports.
[24] Uwe Schulte,et al. Auxiliary GABAB Receptor Subunits Uncouple G Protein βγ Subunits from Effector Channels to Induce Desensitization , 2014, Neuron.
[25] V. Bindokas,et al. A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer's disease Aβ production. , 2013, Cell reports.
[26] P. Hortschansky,et al. Analysis of the Overall Structure of the Multi-Domain Amyloid Precursor Protein (APP) , 2013, PloS one.
[27] Steven A. Connor,et al. The Specific α-Neurexin Interactor Calsyntenin-3 Promotes Excitatory and Inhibitory Synapse Development , 2013, Neuron.
[28] E. Koo,et al. Activity-Induced Convergence of APP and BACE-1 in Acidic Microdomains via an Endocytosis-Dependent Pathway , 2013, Neuron.
[29] E. Holzbaur,et al. JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors , 2013, The Journal of cell biology.
[30] O. Paulsen,et al. Distinct roles of GABAB1a- and GABAB1b-containing GABAB receptors in spontaneous and evoked termination of persistent cortical activity , 2012, The Journal of physiology.
[31] C. Schmidt,et al. Endoplasmic Reticulum Sorting and Kinesin-1 Command the Targeting of Axonal GABAB Receptors , 2012, PloS one.
[32] T. Smart,et al. Sushi domains confer distinct trafficking profiles on GABAB receptors , 2012, Proceedings of the National Academy of Sciences.
[33] M. Gassmann,et al. Regulation of neuronal GABAB receptor functions by subunit composition , 2012, Nature Reviews Neuroscience.
[34] L. Mucke,et al. Alzheimer Mechanisms and Therapeutic Strategies , 2012, Cell.
[35] B. Fakler,et al. Extending the Dynamic Range of Label-free Mass Spectrometric Quantification of Affinity Purifications* , 2011, Molecular & Cellular Proteomics.
[36] J. Harrow,et al. A conditional knockout resource for the genome-wide study of mouse gene function , 2011, Nature.
[37] R. Tanzi,et al. Identification of NEEP21 as a β-Amyloid Precursor Protein-Interacting Protein In Vivo That Modulates Amyloidogenic Processing In Vitro , 2010, The Journal of Neuroscience.
[38] T. Oertner,et al. NMDA receptor-dependent GABAB receptor internalization via CaMKII phosphorylation of serine 867 in GABAB1 , 2010, Proceedings of the National Academy of Sciences.
[39] M. Pangalos,et al. Prolonged activation of NMDA receptors promotes dephosphorylation and alters postendocytic sorting of GABAB receptors , 2010, Proceedings of the National Academy of Sciences.
[40] J. Kapfhammer,et al. The Sushi Domains of GABAB Receptors Function as Axonal Targeting Signals , 2010, The Journal of Neuroscience.
[41] M. Mann,et al. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification , 2008, Nature Biotechnology.
[42] E. Koo,et al. Amyloid Precursor Protein Trafficking, Processing, and Function* , 2008, Journal of Biological Chemistry.
[43] P. S. St George-Hyslop,et al. The in Vivo Brain Interactome of the Amyloid Precursor Protein*S , 2008, Molecular & Cellular Proteomics.
[44] M. Korte,et al. The Secreted β-Amyloid Precursor Protein Ectodomain APPsα Is Sufficient to Rescue the Anatomical, Behavioral, and Electrophysiological Abnormalities of APP-Deficient Mice , 2007, The Journal of Neuroscience.
[45] W. Nelson,et al. Synapses: sites of cell recognition, adhesion, and functional specification. , 2007, Annual review of biochemistry.
[46] Pall I. Olason,et al. A human phenome-interactome network of protein complexes implicated in genetic disorders , 2007, Nature Biotechnology.
[47] G. Woodhall,et al. Depression of Glutamate and GABA Release by Presynaptic GABAB Receptors in the Entorhinal Cortex in Normal and Chronically Epileptic Rats , 2007, Neurosignals.
[48] Kristen M. Harris,et al. Plasticity-Induced Growth of Dendritic Spines by Exocytic Trafficking from Recycling Endosomes , 2006, Neuron.
[49] S. Kaech,et al. Culturing hippocampal neurons , 2006, Nature Protocols.
[50] K. Beyreuther,et al. Subcellular Trafficking of the Amyloid Precursor Protein Gene Family and Its Pathogenic Role in Alzheimer’s Disease , 2006, Neurodegenerative Diseases.
[51] T. Oertner,et al. Differential Compartmentalization and Distinct Functions of GABAB Receptor Variants , 2006, Neuron.
[52] Yaakov Stern,et al. Incidence and Predictors of Seizures in Patients with Alzheimer's Disease , 2006, Epilepsia.
[53] Gordon S. Rule,et al. Fundamentals of Protein NMR Spectroscopy , 2005 .
[54] S. DeKosky,et al. Changes in hippocampal GABABR1 subunit expression in Alzheimer’s patients: association with Braak staging , 2005, Acta Neuropathologica.
[55] Brian O. Smith,et al. Structural Analysis of the Complement Control Protein (CCP) Modules of GABAB Receptor 1a , 2004, Journal of Biological Chemistry.
[56] M. Gallagher,et al. SGS742: the first GABA(B) receptor antagonist in clinical trials. , 2004, Biochemical pharmacology.
[57] Y. Humeau,et al. Redistribution of GABAB(1) Protein and Atypical GABAB Responses in GABAB(2)-Deficient Mice , 2004, The Journal of Neuroscience.
[58] M. Pangalos,et al. Phosphorylation and Chronic Agonist Treatment Atypically Modulate GABAB Receptor Cell Surface Stability* , 2004, Journal of Biological Chemistry.
[59] S. Kins,et al. APP on the move. , 2002, Trends in molecular medicine.
[60] L. Prézeau,et al. C-Terminal Interaction Is Essential for Surface Trafficking But Not for Heteromeric Assembly of GABAB Receptors , 2001, The Journal of Neuroscience.
[61] B. Sommer,et al. Amyloid β interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease , 2000, Nature Neuroscience.
[62] J. Treanor,et al. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. , 1999, Science.
[63] E. Ikonen,et al. Intracellular routing of human amyloid protein precursor: Axonal delivery followed by transport to the dendrites , 1995, Journal of neuroscience research.
[64] D. Selkoe,et al. Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons , 1995, The Journal of cell biology.
[65] A. Gronenborn,et al. A novel, highly stable fold of the immunoglobulin binding domain of streptococcal protein G. , 1993, Science.
[66] J. Penney,et al. Cortical GABAB and GABAA receptors in Alzheimer's disease , 1987, Neurology.
[67] D. Benke. Mechanisms of GABAB receptor exocytosis, endocytosis, and degradation. , 2010, Advances in pharmacology.