Validation of a finite element model of the human metacarpal.

Implant loosening and mechanical failure of components are frequently reported following metacarpophalangeal (MCP) joint replacement. Studies of the mechanical environment of the MCP implant-bone construct are rare. The objective of this study was to evaluate the predictive ability of a finite element model of the intact second human metacarpal to provide a validated baseline for further mechanical studies. A right index human metacarpal was subjected to torsion and combined axial/bending loading using strain gauge (SG) and 3D finite element (FE) analysis. Four different representations of bone material properties were considered. Regression analyses were performed comparing maximum and minimum principal surface strains taken from the SG and FE models. Regression slopes close to unity and high correlation coefficients were found when the diaphyseal cortical shell was modelled as anisotropic and cancellous bone properties were derived from quantitative computed tomography. The inclusion of anisotropy for cortical bone was strongly influential in producing high model validity whereas variation in methods of assigning stiffness to cancellous bone had only a minor influence. The validated FE model provides a tool for future investigations of current and novel MCP joint prostheses.

[1]  K Knutson,et al.  The Swedish Knee Arthroplasty Register 1975-1997: An update with special emphasis on 41,223 knees operated on in 1988-1997 , 2001, Acta orthopaedica Scandinavica.

[2]  R. Huiskes,et al.  Development and validation of a three-dimensional finite element model of the pelvic bone. , 1995, Journal of biomechanical engineering.

[3]  Opitz Jl,et al.  Hand function after metacarpophalangeal joint replacement in rheumatoid arthritis. , 1978 .

[4]  D R Carter,et al.  Mechanical properties and composition of cortical bone. , 1978, Clinical orthopaedics and related research.

[5]  W. Hayes,et al.  Mechanical properties of trabecular bone from the proximal femur: a quantitative CT study. , 1990, Journal of computer assisted tomography.

[6]  H. Gellman,et al.  Silastic metacarpophalangeal joint arthroplasty in patients with rheumatoid arthritis. , 1997, Clinical orthopaedics and related research.

[7]  M Viceconti,et al.  An FEA-based protocol for the pre-clinical validation of custom-made hip implants. , 1998, Journal of medical engineering & technology.

[8]  D. Beevers,et al.  Metacarpophalangeal Joint Prostheses , 1995, Journal of hand surgery.

[9]  T. Keller.  Predicting the compressive mechanical behavior of bone. , 1994, Journal of biomechanics.

[10]  M Lengsfeld,et al.  Comparison of geometry-based and CT voxel-based finite element modelling and experimental validation. , 1998, Medical engineering & physics.

[11]  S. Goldstein,et al.  Evaluation of orthogonal mechanical properties and density of human trabecular bone from the major metaphyseal regions with materials testing and computed tomography , 1991, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[12]  J. Rho,et al.  Anisotropy of Young's modulus of human tibial cortical bone , 2000, Medical and Biological Engineering and Computing.

[13]  M. Akay,et al.  Numerical and experimental stress analysis of a polymeric composite hip joint prosthesis. , 1996, Journal of biomedical materials research.

[14]  [Status of the endoprosthesis in rheumatic metacarpophalangeal joints. Long-term results of metacarpophalangeal prostheses using Swanson's silastic spacers]. , 1996, Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V....

[15]  H. Skinner,et al.  Correlations between orthogonal mechanical properties and density of trabecular bone: use of different densitometric measures. , 1994, Journal of biomedical materials research.

[16]  D. Hose,et al.  Computer Model Analysis of the Swanson and Sutter Metacarpophalangeal Joint Implants , 2000, Journal of hand surgery.

[17]  P Herberts,et al.  Prognosis of total hip replacement: A Swedish multicenter study of 4,664 revisions , 1990 .

[18]  J. Cordey,et al.  Strain gauges used in the mechanical testing of bones. Part I: Theoretical and technical aspects. , 1999, Injury.

[19]  S. G. Fleming,et al.  Metacarpophalangeal Joint Arthroplasty Eleven Year Follow-up Study , 1984, Journal of hand surgery.

[20]  Modélisation d'une prothèse métacarpophalangienne. Comparaisons de l'état de contraintes par la méthode des éléments finis d'une articulation métacarpophalangienne saine et munie d'une prothèse , 2000 .

[21]  C. Jensen,et al.  Silastic arthroplasty in rheumatoid MCP-joints. , 1986, Acta orthopaedica Scandinavica.

[22]  N Verdonschot,et al.  Finite element and experimental models of cemented hip joint reconstructions can produce similar bone and cement strains in pre-clinical tests. , 2002, Journal of biomechanics.

[23]  S. Stover,et al.  Development and validation of a series of three-dimensional finite element models of the equine metacarpus. , 1997, Journal of biomechanics.

[24]  P. McArthur,et al.  A Prospective Randomized Comparison of Sutter and Swanson Silastic Spacers , 1998, Journal of hand surgery.

[25]  Masao Fukunaga,et al.  Quantitative computed tomography: Comparison of two calibration phantoms , 2006, Journal of Bone and Mineral Metabolism.

[26]  B P McNamara,et al.  Relationship between bone-prosthesis bonding and load transfer in total hip reconstruction. , 1997, Journal of biomechanics.

[27]  J. Middleton,et al.  Adaptive finite-element approach for analysis of bone/prosthesis interaction , 2006, Medical and Biological Engineering and Computing.

[28]  R. B. Ashman,et al.  Relations of mechanical properties to density and CT numbers in human bone. , 1995, Medical engineering & physics.

[29]  R. Huiskes,et al.  Mechanical and textural properties of pelvic trabecular bone. , 1993, Journal of biomechanics.

[30]  E A Trowbridge,et al.  An examination of one-piece metacarpophalangeal joint implants using finite element analysis. , 1996, Journal of medical engineering & technology.

[31]  W. Hayes,et al.  The compressive behavior of bone as a two-phase porous structure. , 1977, The Journal of bone and joint surgery. American volume.

[32]  E Y Chao,et al.  A survey of finite element analysis in orthopedic biomechanics: the first decade. , 1983, Journal of biomechanics.

[33]  R. L. Linscheid,et al.  Forces in the normal and abnormal hand , 1985, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[34]  J H Keyak,et al.  Validation of an automated method of three-dimensional finite element modelling of bone. , 1993, Journal of biomedical engineering.

[35]  L. Mannerfelt,et al.  Silastic arthroplasty of the metacarpophalangeal joints in rheumatoid arthritis , 1975 .

[36]  P Gebuhr,et al.  Silastic arthroplasty in rheumatoid MCP-joints. 60 joints followed for 7 years. , 1994, Acta orthopaedica Scandinavica.

[37]  P S Walker,et al.  A new approach to the fixation of a metacarpophalangeal joint prosthesis. , 1983, Engineering in medicine.

[38]  J. Taylor.  An Introduction to Error Analysis , 1982 .

[39]  A. Burstein,et al.  The Mechanical Properties of Cortical Bone , 1974 .

[40]  J. Jeffs,et al.  Experience with Silastic prostheses in the rheumatoid hand. A 5-year follow-up. , 1978, Annals of the rheumatic diseases.