Thromboxane A2-receptor blockade improves cerebral protection for deep hypothermic circulatory arrest.

[1]  M. Davies,et al.  Nitric oxide production affects cerebral perfusion and metabolism after deep hypothermic circulatory arrest. , 1996, The Annals of thoracic surgery.

[2]  M. Tsuji,et al.  Effects of cerebroplegic solutions during hypothermic circulatory arrest and short-term recovery. , 1994, The Journal of thoracic and cardiovascular surgery.

[3]  O. Dapunt,et al.  Cerebral effects of low-flow cardiopulmonary bypass and hypothermic circulatory arrest. , 1994, The Annals of thoracic surgery.

[4]  D. Hearse,et al.  Thromboxane A2 mediates pulmonary hypertension after cardiopulmonary bypass in the rabbit. , 1993, The Journal of thoracic and cardiovascular surgery.

[5]  K. Lindpaintner,et al.  Characterization of endothelin synthetic pathways and receptor subtypes: physiological and pathophysiological implications. , 1993 .

[6]  J. Ware,et al.  A comparison of the perioperative neurologic effects of hypothermic circulatory arrest versus low-flow cardiopulmonary bypass in infant heart surgery. , 1993, The New England journal of medicine.

[7]  M. Tsuji,et al.  Recovery of cerebral blood flow and energy state in piglets after hypothermic circulatory arrest versus recovery after low-flow bypass. , 1993, The Journal of thoracic and cardiovascular surgery.

[8]  C. Piantadosi,et al.  Recovery of cerebral metabolism and mitochondrial oxidation state is delayed after hypothermic circulatory arrest. , 1991, Circulation.

[9]  M. Nakashima,et al.  Pharmacokinetic and Pharmacodynamic Profiles of Vapiprost, a Selective, Long‐Lasting Thromboxane Receptor Antagonist, After Single and Multiple Oral Administration to Healthy Volunteers , 1991, Journal of clinical pharmacology.

[10]  W. Dreyer,et al.  Neutrophil Accumulation in Ischemic Canine Myocardium: Insights Into Time Course, Distribution, and Mechanism of Localization During Early Reperfusion , 1991, Circulation.

[11]  J G Reves,et al.  The effect of hypothermic cardiopulmonary bypass and total circulatory arrest on cerebral metabolism in neonates, infants, and children. , 1991, The Journal of thoracic and cardiovascular surgery.

[12]  M. Takaoka,et al.  Phosphoramidon, a metalloproteinase inhibitor, suppresses the hypertensive effect of big endothelin-1. , 1990, European journal of pharmacology.

[13]  K. Ohnaka,et al.  Identification and characterization of endothelin converting activity in cultured bovine endothelial cells. , 1990, Biochemical and biophysical research communications.

[14]  B. P. White,et al.  GR32191, a highly potent and specific thromboxane A2 receptor blocking drug on platelets and vascular and airways smooth muscle in vitro , 1989, British journal of pharmacology.

[15]  J G Reves,et al.  The effects of deep hypothermic cardiopulmonary bypass and total circulatory arrest on cerebral blood flow in infants and children. , 1989, The Journal of thoracic and cardiovascular surgery.

[16]  M. Yanagisawa,et al.  The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[17]  T. Yaksh,et al.  Time Course of Release in vivo of PGE2, PGF2α, 6-Keto-PGF1α, and TxB2 into the Brain Extracellular Space after 15 Min of Complete Global Ischemia in the Presence and Absence of Cyclooxygenase Inhibition , 1988, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[18]  Z. Katušić,et al.  Endothelium-derived contracting factor: endothelin and/or superoxide anion? , 1988, Trends in pharmacological sciences.

[19]  A. Matsumori,et al.  Increased Synthesis and Secretion of Atrial Natriuretic Polypeptide During Viral Myocarditis , 1988, Journal of cardiovascular pharmacology.

[20]  Sadao Kimura,et al.  A novel potent vasoconstrictor peptide produced by vascular endothelial cells , 1988, Nature.

[21]  P. Vanhoutte,et al.  Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. , 1986, The American journal of physiology.

[22]  H. Kontos.  George E. Brown memorial lecture. Oxygen radicals in cerebral vascular injury. , 1985, Circulation research.

[23]  F. Wells,et al.  Duration of circulatory arrest does influence the psychological development of children after cardiac operation in early life. , 1983, The Journal of thoracic and cardiovascular surgery.

[24]  R. A. Coleman,et al.  Studies on the characterisation of prostanoid receptors: a proposed classification. , 1982, Prostaglandins.

[25]  C. Seachord,et al.  A dominant role of thromboxane formation in secondary aggregation of platelets , 1979, Nature.

[26]  J. Dobbing,et al.  Comparative aspects of the brain growth spurt. , 1979, Early human development.

[27]  J. Vane,et al.  Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin. , 1978, Pharmacological reviews.

[28]  M. Hamberg,et al.  Thromboxane A2: effects on airway and vascular smooth muscle. , 1977, Prostaglandins.

[29]  J I Hoffman,et al.  Blood flow measurements with radionuclide-labeled particles. , 1977, Progress in cardiovascular diseases.

[30]  J. Mault,et al.  Cerebral metabolism and circulatory arrest: effects of duration and strategies for protection. , 1993, The Annals of thoracic surgery.

[31]  R. Ikegawa,et al.  Phosphoramidon prevents cerebral vasospasm following subarachnoid hemorrhage in dogs: the relationship to endothelin-1 levels in the cerebrospinal fluid. , 1991, Life sciences.

[32]  W. Meadow,et al.  Internal jugular venous oxygen saturation does not reflect sagittal sinus oxygen saturation in piglets. , 1991, Biology of the neonate.

[33]  E. Hornby,et al.  Pathophysiological actions of thromboxane A2 and their pharmacological antagonism by thromboxane receptor blockade with GR32191. , 1990, Circulation.

[34]  M. Yanagisawa,et al.  Conversion of Big Endothelin‐1 to 21‐Residue Endothelin‐1 Is Essential for Expression of Full Vasoconstrictor Activity: Structure‐Activity Relationships of Big Endothelin‐1 , 1989, Journal of cardiovascular pharmacology.

[35]  R. Wallis,et al.  Role of thromboxane A2. , 1985, Advances in experimental medicine and biology.

[36]  W. Pond,et al.  The biology of the pig , 1978 .