Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN

[1]  Swarnali Acharyya,et al.  Understanding cachexia in the context of metastatic progression , 2020, Nature Reviews Cancer.

[2]  C. Matthews,et al.  Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable , 2019, Medicine and science in sports and exercise.

[3]  R. Newton,et al.  The Exercise and Sports Science Australia position statement: Exercise medicine in cancer management. , 2019, Journal of science and medicine in sport.

[4]  Michael C. Ostrowski,et al.  Modeling Human Cancer-induced Cachexia , 2019, Cell reports.

[5]  U. Wisløff,et al.  Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity , 2018, Scientific Reports.

[6]  J. Ruas,et al.  Transcriptomic analysis of the development of skeletal muscle atrophy in cancer-cachexia in tumor-bearing mice. , 2018, Physiological genomics.

[7]  F. López‐Soriano,et al.  Inter-tissue communication in cancer cachexia , 2018, Nature Reviews Endocrinology.

[8]  Martin Eisenacher,et al.  The PRIDE database and related tools and resources in 2019: improving support for quantification data , 2018, Nucleic Acids Res..

[9]  R. Chammas,et al.  18F‐Fluoride PET/CT and 99mTc‐MDP SPECT/CT can detect bone cancer at early stage in rodents , 2018, Life sciences.

[10]  R. Chammas,et al.  High‐intensity interval training slows down tumor progression in mice bearing Lewis lung carcinoma , 2018, JCSM Rapid Communications.

[11]  S. Kaasa,et al.  Cancer cachexia: rationale for the MENAC (Multimodal—Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial , 2018, BMJ Supportive & Palliative Care.

[12]  Christiano R. R. Alves,et al.  Effects of N‐acetylcysteine on isolated skeletal muscle contractile properties after an acute bout of aerobic exercise , 2017, Life sciences.

[13]  J. Carson,et al.  Linking Cancer Cachexia-Induced Anabolic Resistance to Skeletal Muscle Oxidative Metabolism , 2017, Oxidative medicine and cellular longevity.

[14]  J. Carson,et al.  Mitochondrial degeneration precedes the development of muscle atrophy in progression of cancer cachexia in tumour‐bearing mice , 2017, Journal of cachexia, sarcopenia and muscle.

[15]  C. Scavone,et al.  Exercise training decreases NADPH oxidase activity and restores skeletal muscle mass in heart failure rats. , 2017, Journal of applied physiology.

[16]  H. Middlekauff,et al.  Exercise training improves neurovascular control and calcium cycling gene expression in patients with heart failure with cardiac resynchronization therapy. , 2016, American journal of physiology. Heart and circulatory physiology.

[17]  Y. Loh,et al.  Cops2 promotes pluripotency maintenance by Stabilizing Nanog Protein and Repressing Transcription , 2016, Scientific Reports.

[18]  Rosmin Elsa Mohan,et al.  Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia , 2016, Nature Medicine.

[19]  W. I. Mohamed,et al.  Cullin–RING ubiquitin E3 ligase regulation by the COP9 signalosome , 2016, Nature.

[20]  I. Nookaew,et al.  Voluntary Running Suppresses Tumor Growth through Epinephrine- and IL-6-Dependent NK Cell Mobilization and Redistribution. , 2016, Cell metabolism.

[21]  E. Wagner,et al.  Mechanisms of metabolic dysfunction in cancer-associated cachexia , 2016, Genes & development.

[22]  M. Eens,et al.  Vitally important – does early innate immunity predict recruitment and adult innate immunity? , 2016, Ecology and evolution.

[23]  P. Porporato.  Understanding cachexia as a cancer metabolism syndrome , 2016, Oncogenesis.

[24]  B. Saltin,et al.  Exercise as medicine – evidence for prescribing exercise as therapy in 26 different chronic diseases , 2015, Scandinavian journal of medicine & science in sports.

[25]  F. López‐Soriano,et al.  Combination of exercise training and erythropoietin prevents cancer-induced muscle alterations , 2015, Oncotarget.

[26]  Tessa R Werner,et al.  Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia , 2015, Molecular metabolism.

[27]  Heng Zhu,et al.  Identification of Serum Biomarkers for Gastric Cancer Diagnosis Using a Human Proteome Microarray* , 2015, Molecular & Cellular Proteomics.

[28]  D. Guttridge.  A TGF-β pathway associated with cancer cachexia , 2015, Nature Medicine.

[29]  Masahiro Endo,et al.  Prognostic impact of cancer cachexia in patients with advanced non-small cell lung cancer , 2015, Supportive Care in Cancer.

[30]  Christiano R. R. Alves,et al.  Aerobic exercise training as therapy for cardiac and cancer cachexia. , 2015, Life sciences.

[31]  Gregory Palmer,et al.  Modulation of Murine Breast Tumor Vascularity, Hypoxia, and Chemotherapeutic Response by Exercise , 2015, Journal of the National Cancer Institute.

[32]  B. Pedersen,et al.  Exercise as an anti-inflammatory therapy for rheumatic diseases—myokine regulation , 2015, Nature Reviews Rheumatology.

[33]  Matthew E. Ritchie,et al.  limma powers differential expression analyses for RNA-sequencing and microarray studies , 2015, Nucleic acids research.

[34]  H. Middlekauff,et al.  Molecular basis for the improvement in muscle metaboreflex and mechanoreflex control in exercise-trained humans with chronic heart failure. , 2014, American journal of physiology. Heart and circulatory physiology.

[35]  F. López‐Soriano,et al.  Cancer cachexia: understanding the molecular basis , 2014, Nature Reviews Cancer.

[36]  E. Wagner,et al.  A switch from white to brown fat increases energy expenditure in cancer-associated cachexia. , 2014, Cell metabolism.

[37]  C. Scavone,et al.  NADPH oxidase hyperactivity induces plantaris atrophy in heart failure rats. , 2014, International journal of cardiology.

[38]  U. Hassiepen,et al.  Crystal structure of the human COP9 signalosome , 2014, Nature.

[39]  B. Spiegelman,et al.  Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia , 2014, Nature.

[40]  C. Yauk,et al.  Thyroid Hormone Response Element Half-Site Organization and Its Effect on Thyroid Hormone Mediated Transcription , 2014, PloS one.

[41]  P. Brum,et al.  Skeletal myopathy in heart failure: effects of aerobic exercise training , 2014, Experimental physiology.

[42]  R. Evans,et al.  Nuclear Receptors, RXR, and the Big Bang , 2014, Cell.

[43]  C. Croce,et al.  Microvesicles containing miRNAs promote muscle cell death in cancer cachexia via TLR7 , 2014, Proceedings of the National Academy of Sciences.

[44]  U. Wisløff,et al.  Autophagy Signaling in Skeletal Muscle of Infarcted Rats , 2014, PloS one.

[45]  E. Barreiro,et al.  Mitochondrial dysfunction and therapeutic approaches in respiratory and limb muscles of cancer cachectic mice , 2013, Experimental physiology.

[46]  Y. Tseng,et al.  Increased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1- and CD36-mediated fatty acid uptake. , 2013, Antioxidants & redox signaling.

[47]  Adam W. Beharry,et al.  Diaphragm and ventilatory dysfunction during cancer cachexia , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[48]  M. Mindrinos,et al.  Skeletal muscle mitochondrial uncoupling in a murine cancer cachexia model , 2013, International journal of oncology.

[49]  U. Wisløff,et al.  High- versus moderate-intensity aerobic exercise training effects on skeletal muscle of infarcted rats. , 2013, Journal of applied physiology.

[50]  J. Zierath,et al.  Exercise metabolism and the molecular regulation of skeletal muscle adaptation. , 2013, Cell metabolism.

[51]  J. McDunn,et al.  Metabolic derangements in the gastrocnemius and the effect of Compound A therapy in a murine model of cancer cachexia , 2013, Journal of cachexia, sarcopenia and muscle.

[52]  J. Campos,et al.  Exercise Training Restores Cardiac Protein Quality Control in Heart Failure , 2012, PloS one.

[53]  D. Glass,et al.  Cancer cachexia: mediators, signaling, and metabolic pathways. , 2012, Cell metabolism.

[54]  U. Wisløff,et al.  Exercise Training Prevents Oxidative Stress and Ubiquitin-Proteasome System Overactivity and Reverse Skeletal Muscle Atrophy in Heart Failure , 2012, PloS one.

[55]  David Goldberg,et al.  Preview: a program for surveying shotgun proteomics tandem mass spectrometry data. , 2011, Analytical chemistry.

[56]  F. López‐Soriano,et al.  Combined approach to counteract experimental cancer cachexia: eicosapentaenoic acid and training exercise , 2011, Journal of cachexia, sarcopenia and muscle.

[57]  Stephan von Haehling,et al.  An overview of sarcopenia: facts and numbers on prevalence and clinical impact , 2010, Journal of cachexia, sarcopenia and muscle.

[58]  M. Mindrinos,et al.  Nuclear magnetic resonance in conjunction with functional genomics suggests mitochondrial dysfunction in a murine model of cancer cachexia , 2010, International journal of molecular medicine.

[59]  Rafael A. Irizarry,et al.  A framework for oligonucleotide microarray preprocessing , 2010, Bioinform..

[60]  Pedro M. Valero-Mora,et al.  ggplot2: Elegant Graphics for Data Analysis , 2010 .

[61]  R. Dominguez,et al.  Regulation of actin cytoskeleton dynamics in cells , 2010, Molecules and cells.

[62]  C. Cray,et al.  Acute phase response in animals: a review. , 2009, Comparative medicine.

[63]  Hadley Wickham,et al.  ggplot2 - Elegant Graphics for Data Analysis (2nd Edition) , 2017 .

[64]  S. Anker,et al.  The Xanthine Oxidase Inhibitors Oxypurinol and Allopurinol Reduce Wasting and Improve Cardiac Function in Experimental Cancer Cachexia , 2009 .

[65]  É. Caperuto,et al.  Effect of endurance training upon lipid metabolism in the liver of cachectic tumour‐bearing rats , 2008, Cell biochemistry and function.

[66]  U. Wisløff,et al.  Aerobic Interval Training Versus Continuous Moderate Exercise as a Treatment for the Metabolic Syndrome: A Pilot Study , 2008, Circulation.

[67]  L. Poole,et al.  Discovering mechanisms of signaling-mediated cysteine oxidation. , 2008, Current opinion in chemical biology.

[68]  M. Moraes,et al.  Effect of a High-Intensity Exercise Training on the Metabolism and Function of Macrophages and Lymphocytes of Walker 256 Tumor–Bearing Rats , 2007, Experimental biology and medicine.

[69]  Godfrey L. Smith,et al.  Superior Cardiovascular Effect of Aerobic Interval Training Versus Moderate Continuous Training in Heart Failure Patients: A Randomized Study , 2007, Circulation.

[70]  W. Hong,et al.  Alien interacts with the human androgen receptor and inhibits prostate cancer cell growth. , 2007, Molecular endocrinology.

[71]  L. Mao,et al.  Oxidative phenotype protects myofibers from pathological insults induced by chronic heart failure in mice. , 2007, The American journal of pathology.

[72]  A. Baniahmad,et al.  The coregulator Alien , 2007, Nuclear receptor signaling.

[73]  Swarnali Acharyya,et al.  Dystrophin glycoprotein complex dysfunction: a regulatory link between muscular dystrophy and cancer cachexia. , 2005, Cancer cell.

[74]  D. Mangelsdorf,et al.  Retinoid x receptor heterodimers in the metabolic syndrome. , 2005, The New England journal of medicine.

[75]  X. Deng,et al.  Disruption of the COP9 Signalosome Csn2 Subunit in Mice Causes Deficient Cell Proliferation, Accumulation of p53 and Cyclin E, and Early Embryonic Death , 2003, Molecular and Cellular Biology.

[76]  E. Babu,et al.  Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells. , 2002, Biochimica et biophysica acta.

[77]  C. Bing,et al.  Muscle UCP-3 mRNA levels are elevated in weight loss associated with gastrointestinal adenocarcinoma in humans , 2002, British Journal of Cancer.

[78]  T. Visser,et al.  Thyroid Hormone Transport by the Heterodimeric Human System L Amino Acid Transporter. , 2001, Endocrinology.

[79]  M. Eggert,et al.  Alien, a Highly Conserved Protein with Characteristics of a Corepressor for Members of the Nuclear Hormone Receptor Superfamily , 1999, Molecular and Cellular Biology.

[80]  M. H. de Keijzer,et al.  Evaluation of a biosensor for the measurement of lactate in whole blood. , 1999, Clinical biochemistry.

[81]  C. Shoemaker,et al.  Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family , 1998, Nature.

[82]  T. Perlmann,et al.  Retinoic Acid Receptor/Retinoid X Receptor Heterodimers Can Be Activated through Both Subunits Providing a Basis for Synergistic Transactivation and Cellular Differentiation* , 1997, The Journal of Biological Chemistry.

[83]  P. Silver,et al.  MyoD is required for myogenic stem cell function in adult skeletal muscle. , 1996, Genes & development.

[84]  R. Evans,et al.  The RXR heterodimers and orphan receptors , 1995, Cell.

[85]  M. Pfahl,et al.  A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily , 1994, Molecular and cellular biology.

[86]  T. Svitkina.  The Actin Cytoskeleton and Actin-Based Motility. , 2018, Cold Spring Harbor perspectives in biology.

[87]  L. Jones,et al.  Bench-to-Bedside Approaches for Personalized Exercise Therapy in Cancer. , 2017, American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.

[88]  S. Gielen,et al.  Exercise training in patients with heart disease: review of beneficial effects and clinical recommendations. , 2015, Progress in cardiovascular diseases.

[89]  R Core Team,et al.  R: A language and environment for statistical computing. , 2014 .

[90]  T. Saraswathi,et al.  Cancer cachexia , 2011, Journal of oral and maxillofacial pathology : JOMFP.

[91]  Jürgen Cox,et al.  A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics , 2009, Nature Protocols.

[92]  A. Kramer,et al.  Be smart, exercise your heart: exercise effects on brain and cognition , 2008, Nature Reviews Neuroscience.

[93]  J. Krieger,et al.  Exercise training delays cardiac dysfunction and prevents calcium handling abnormalities in sympathetic hyperactivity-induced heart failure mice. , 2008, Journal of applied physiology.

[94]  P. Ortner,et al.  Multinational Association of Supportive Care in Cancer , 2008, Supportive Care in Cancer.

[95]  M. Rudnicki,et al.  bFGF and LIF signaling activates STAT3 in proliferating myoblasts. , 1996, Developmental genetics.