Activation of cyclin D1-kinase in murine fibroblasts lacking both p21Cip1 and p27Kip1

[1]  A. Lenferink,et al.  ErbB2/Neu-Induced, Cyclin D1-Dependent Transformation Is Accelerated in p27-Haploinsufficient Mammary Epithelial Cells but Impaired in p27-Null Cells , 2002, Molecular and Cellular Biology.

[2]  M. Barbacid,et al.  Cyclin D-dependent kinases, INK4 inhibitors and cancer. , 2002, Biochimica et biophysica acta.

[3]  J. Albrecht,et al.  C/EBPα triggers proteasome‐dependent degradation of cdk4 during growth arrest , 2002 .

[4]  S. Rane,et al.  Germ Line Transmission of the Cdk4R24C Mutation Facilitates Tumorigenesis and Escape from Cellular Senescence , 2002, Molecular and Cellular Biology.

[5]  M. Barbacid,et al.  To cycle or not to cycle: a critical decision in cancer , 2001, Nature reviews. Cancer.

[6]  Triona Goode,et al.  C/EBPα Arrests Cell Proliferation through Direct Inhibition of Cdk2 and Cdk4 , 2001 .

[7]  M. Barbacid,et al.  Invasive melanoma in Cdk4-targeted mice , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[8]  M. Tiainen,et al.  Reconstitution of Cyclin D1-Associated Kinase Activity Drives Terminally Differentiated Cells into the Cell Cycle , 2001, Molecular and Cellular Biology.

[9]  J. Bonventre,et al.  TRIP‐Br: a novel family of PHD zinc finger‐ and bromodomain‐interacting proteins that regulate the transcriptional activity of E2F‐1/DP‐1 , 2001, The EMBO journal.

[10]  G. Peters,et al.  Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence , 2001, Nature.

[11]  Jiri Bartek,et al.  Phosphorylation‐dependent and ‐independent functions of p130 cooperate to evoke a sustained G1 block , 2001, The EMBO journal.

[12]  J L Cleveland,et al.  Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. , 2000, Genes & development.

[13]  W. J. Pledger,et al.  Analysis of Cyclin D3-cdk4 Complexes in Fibroblasts Expressing and Lacking p27kip1 and p21cip1 , 2000, Molecular and Cellular Biology.

[14]  N. Dyson,et al.  Requirements for cell cycle arrest by p16INK4a. , 2000, Molecular cell.

[15]  J. R. Smith,et al.  Complex mechanisms underlying impaired activation of Cdk4 and Cdk2 in replicative senescence: roles of p16, p21, and cyclin D1. , 1999, Experimental cell research.

[16]  Xiaohang Zhao,et al.  Direct inhibition of G1 cdk kinase activity by MyoD promotes myoblast cell cycle withdrawal and terminal differentiation , 1999, The EMBO journal.

[17]  I. Hampson,et al.  Regulation of CDK4 activity by a novel CDK4-binding protein, p34(SEI-1). , 1999, Genes & development.

[18]  P. Pandolfi,et al.  Targeted Disruption of CDK4 Delays Cell Cycle Entry with Enhanced p27Kip1 Activity , 1999, Molecular and Cellular Biology.

[19]  J. Harbour,et al.  Cdk Phosphorylation Triggers Sequential Intramolecular Interactions that Progressively Block Rb Functions as Cells Move through G1 , 1999, Cell.

[20]  James M. Roberts,et al.  CDK inhibitors: positive and negative regulators of G1-phase progression. , 1999, Genes & development.

[21]  Rene H Medema,et al.  Rescue of Cyclin D1 Deficiency by Knockin Cyclin E , 1999, Cell.

[22]  M. Herlyn,et al.  Induction of p21WAF1/CIP1and Inhibition of Cdk2 Mediated by the Tumor Suppressor p16INK4a , 1999, Molecular and Cellular Biology.

[23]  M. Barbacid,et al.  Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in β-islet cell hyperplasia , 1999, Nature Genetics.

[24]  James M. Roberts,et al.  The p21Cip1 and p27Kip1 CDK ‘inhibitors’ are essential activators of cyclin D‐dependent kinases in murine fibroblasts , 1999, The EMBO journal.

[25]  G. Peters,et al.  Induced Expression of p16INK4a Inhibits Both CDK4- and CDK2-Associated Kinase Activity by Reassortment of Cyclin-CDK-Inhibitor Complexes , 1999, Molecular and Cellular Biology.

[26]  E. Lees,et al.  Cyclin D-CDK Subunit Arrangement Is Dependent on the Availability of Competing INK4 and p21 Class Inhibitors , 1999, Molecular and Cellular Biology.

[27]  W. J. Pledger,et al.  Cyclin D3-associated kinase activity is regulated by p27kip1 in BALB/c 3T3 cells. , 1998, Molecular biology of the cell.

[28]  M. Roussel,et al.  Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[29]  Robert A. Weinberg,et al.  Functional Inactivation of the Retinoblastoma Protein Requires Sequential Modification by at Least Two Distinct Cyclin-cdk Complexes , 1998, Molecular and Cellular Biology.

[30]  J. Massagué,et al.  Differential Interaction of the Cyclin-dependent Kinase (Cdk) Inhibitor p27Kip1 with Cyclin A-Cdk2 and Cyclin D2-Cdk4* , 1997, The Journal of Biological Chemistry.

[31]  J. LaBaer,et al.  New functional activities for the p21 family of CDK inhibitors. , 1997, Genes & development.

[32]  J. Massagué,et al.  The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2. , 1997, Genes & development.

[33]  M. Kitagawa,et al.  The consensus motif for phosphorylation by cyclin D1‐Cdk4 is different from that for phosphorylation by cyclin A/E‐Cdk2. , 1996, The EMBO journal.

[34]  S. Reed,et al.  Different roles for cyclins D1 and E in regulation of the G1-to-S transition , 1995, Molecular and cellular biology.

[35]  James M. Roberts,et al.  Cloning of p27 Kip1 , a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals , 1994, Cell.

[36]  Tony Hunter,et al.  p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21 , 1994, Cell.

[37]  S. Shurtleff,et al.  D-type cyclin-dependent kinase activity in mammalian cells , 1994, Molecular and cellular biology.

[38]  J. R. Smith,et al.  Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. , 1994, Experimental cell research.

[39]  C. Turck,et al.  Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit , 1993, Nature.

[40]  David Beach,et al.  p21 is a universal inhibitor of cyclin kinases , 1993, Nature.

[41]  S. Elledge,et al.  The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases , 1993, Cell.

[42]  J. Trent,et al.  WAF1, a potential mediator of p53 tumor suppression , 1993, Cell.