Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity

[1]  R. Wilkinson,et al.  IFN--and TNF-Independent Vitamin D-Inducible Human Suppression of Mycobacteria: The Role of Cathelicidin LL-37 , 2007 .

[2]  P. Dhawan,et al.  Induction of cathelicidin in normal and CF bronchial epithelial cells by 1,25-dihydroxyvitamin D(3). , 2007, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

[3]  J. Aloia,et al.  Re: epidemic influenza and vitamin D. , 2007, Epidemiology and infection.

[4]  J. Todd,et al.  Association of the Vitamin D Metabolism Gene CYP27B1 With Type 1 Diabetes , 2007, Diabetes.

[5]  Sara Gandini,et al.  Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. , 2007, Archives of internal medicine.

[6]  R. Modlin,et al.  Cutting Edge: Vitamin D-Mediated Human Antimicrobial Activity against Mycobacterium tuberculosis Is Dependent on the Induction of Cathelicidin1 , 2007, The Journal of Immunology.

[7]  P. Lipsky,et al.  Modulatory Effects of 1,25-Dihydroxyvitamin D3 on Human B Cell Differentiation , 2007, The Journal of Immunology.

[8]  Robert J Wilkinson,et al.  A single dose of vitamin D enhances immunity to mycobacteria. , 2007, American journal of respiratory and critical care medicine.

[9]  C. Mathieu,et al.  Mechanism and potential of the growth-inhibitory actions of vitamin D and ana-logs. , 2007, Current medicinal chemistry.

[10]  J. Söderlund,et al.  The antimicrobial peptide LL-37 inhibits HIV-1 replication. , 2007, Current HIV research.

[11]  Robert J Wilkinson,et al.  IFN-γ- and TNF-Independent Vitamin D-Inducible Human Suppression of Mycobacteria: The Role of Cathelicidin LL-371 , 2007, The Journal of Immunology.

[12]  D. Eyles,et al.  Vitamin D deficiency during various stages of pregnancy in the rat; its impact on development and behaviour in adult offspring , 2007, Psychoneuroendocrinology.

[13]  P. Lips,et al.  13th Workshop consensus for vitamin D nutritional guidelines , 2007, The Journal of Steroid Biochemistry and Molecular Biology.

[14]  Junliang Pan,et al.  DCs metabolize sunlight-induced vitamin D3 to 'program' T cell attraction to the epidermal chemokine CCL27 , 2007, Nature Immunology.

[15]  A. Sher,et al.  Cooperation of Toll-like receptor signals in innate immune defence , 2007, Nature Reviews Immunology.

[16]  Y. Helfrich,et al.  Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. , 2007, The Journal of clinical investigation.

[17]  A. Ascherio,et al.  Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. , 2006, JAMA.

[18]  C. Doglioni,et al.  Treatment of Experimental Autoimmune Prostatitis in Nonobese Diabetic Mice by the Vitamin D Receptor Agonist Elocalcitol1 , 2006, The Journal of Immunology.

[19]  S. Romagnani.  Regulation of the T cell response , 2006, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[20]  K. Badenhoop,et al.  Protection From Type 1 Diabetes by Vitamin D Receptor Haplotypes , 2006, Annals of the New York Academy of Sciences.

[21]  S. Madronich,et al.  Epidemic influenza and vitamin D , 2006, Epidemiology and Infection.

[22]  A. Zittermann.  Vitamin D and disease prevention with special reference to cardiovascular disease. , 2006, Progress in biophysics and molecular biology.

[23]  R. Gallo,et al.  Control of the innate epithelial antimicrobial response is cell‐type specific and dependent on relevant microenvironmental stimuli , 2006, Immunology.

[24]  P. Hershberger,et al.  The antitumor efficacy of calcitriol: preclinical studies. , 2006, Anticancer research.

[25]  Yan Liu,et al.  Prospective study of predictors of vitamin D status and cancer incidence and mortality in men. , 2006, Journal of the National Cancer Institute.

[26]  Maureen L. Coleman,et al.  Genomic Islands and the Ecology and Evolution of Prochlorococcus , 2006, Science.

[27]  D. Tamandl,et al.  Vitamin D3 down‐regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen‐associated molecular patterns , 2006, European journal of immunology.

[28]  C. Rumende,et al.  The effect of vitamin D as supplementary treatment in patients with moderately advanced pulmonary tuberculous lesion. , 2006, Acta medica Indonesiana.

[29]  A. Ponsonby,et al.  UVR, Vitamin D and Three Autoimmune Diseases—Multiple Sclerosis, Type 1 Diabetes, Rheumatoid Arthritis , 2005, Photochemistry and photobiology.

[30]  M. Campbell,et al.  Biological actions of extra-renal 25-hydroxyvitamin D-1α-hydroxylase and implications for chemoprevention and treatment , 2005, The Journal of Steroid Biochemistry and Molecular Biology.

[31]  H. Koeffler,et al.  Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up‐regulated in myeloid cells by 1,25‐dihydroxyvitamin D3 , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[32]  M. Horowitz,et al.  Relationship between fasting serum glucose, age, body mass index and serum 25 hydroxyvitamin D in postmenopausal women , 2005, Clinical endocrinology.

[33]  L. Nguyen,et al.  Alternative Splicing of Vitamin D-24-Hydroxylase , 2005, Journal of Biological Chemistry.

[34]  M. Guy,et al.  Autocrine Metabolism of Vitamin D in Normal and Malignant Breast Tissue , 2005, Clinical Cancer Research.

[35]  H. Törmä,et al.  Vitamin D induces the antimicrobial protein hCAP18 in human skin. , 2005, The Journal of investigative dermatology.

[36]  P. Lips,et al.  Estimates of optimal vitamin D status , 2005, Osteoporosis International.

[37]  S. Harris.  Vitamin D in type 1 diabetes prevention. , 2005, The Journal of nutrition.

[38]  J. McGrath,et al.  Distribution of the Vitamin D receptor and 1α-hydroxylase in human brain , 2005, Journal of Chemical Neuroanatomy.

[39]  N. Kagawa,et al.  Metabolism of vitamin D3 by cytochromes P450. , 2005, Frontiers in bioscience : a journal and virtual library.

[40]  H. DeLuca.  Overview of general physiologic features and functions of vitamin D. , 2004, The American journal of clinical nutrition.

[41]  John H. White,et al.  Cutting Edge: 1,25-Dihydroxyvitamin D3 Is a Direct Inducer of Antimicrobial Peptide Gene Expression , 2004, The Journal of Immunology.

[42]  S. Hankinson,et al.  Plasma vitamin D metabolites and risk of colorectal cancer in women. , 2004, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[43]  F. Wrba,et al.  25-Hydroxyvitamin D3-1α-hydroxylase Expression in Normal and Malignant Human Colon , 2004, Journal of Histochemistry and Cytochemistry.

[44]  M. Willingham,et al.  Pancreatic cancer cells express 25-hydroxyvitamin D-1α-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3 , 2004 .

[45]  M. Hewison,et al.  Expression of 25-hydroxyvitamin D3-1α-hydroxylase in pancreatic islets , 2004, The Journal of Steroid Biochemistry and Molecular Biology.

[46]  C. Mathieu,et al.  Vitamin D deficiency in early life accelerates Type 1 diabetes in non-obese diabetic mice , 2004, Diabetologia.

[47]  M. Hakama,et al.  Prostate cancer risk and prediagnostic serum 25-hydroxyvitamin D levels (Finland) , 2000, Cancer Causes & Control.

[48]  J. Cerhan,et al.  Vitamin D intake is inversely associated with rheumatoid arthritis: results from the Iowa Women's Health Study. , 2004, Arthritis and rheumatism.

[49]  Aristides G. Eliopoulos,et al.  Differential Regulation of Vitamin D Receptor and Its Ligand in Human Monocyte-Derived Dendritic Cells1 , 2003, The Journal of Immunology.

[50]  G. Tenderich,et al.  Low vitamin D status: a contributing factor in the pathogenesis of congestive heart failure? , 2003, Journal of the American College of Cardiology.

[51]  A. Ponsonby,et al.  Ultraviolet radiation and autoimmune disease: insights from epidemiological research. , 2002, Toxicology.

[52]  M. Holick,et al.  25-Hydroxyvitamin D-1α-hydroxylase activity is diminished in human prostate cancer cells and is enhanced by gene transfer , 2002, The Journal of Steroid Biochemistry and Molecular Biology.

[53]  M. Uskoković,et al.  A 1α,25-Dihydroxyvitamin D3 Analog Enhances Regulatory T-Cells and Arrests Autoimmune Diabetes in NOD Mice , 2002 .

[54]  C. Mathieu,et al.  The coming of age of 1,25-dihydroxyvitamin D(3) analogs as immunomodulatory agents. , 2002, Trends in Molecular Medicine.

[55]  D. Chant,et al.  Long-term trends in sunshine duration and its association with schizophrenia birth rates and age at first registration — data from Australia and the Netherlands , 2002, Schizophrenia Research.

[56]  W. Grant.  An estimate of premature cancer mortality in the U.S. due to inadequate doses of solar ultraviolet‐B radiation , 2002, Cancer.

[57]  David F. Richards,et al.  In Vitro Generation of Interleukin 10–producing Regulatory CD4+ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines , 2002, The Journal of experimental medicine.

[58]  M. Uskoković,et al.  A 1 , 25-Dihydroxyvitamin D 3 Analog Enhances Regulatory T-Cells and Arrests Autoimmune Diabetes in NOD Mice , 2002 .

[59]  H. DeLuca,et al.  Vitamin D: its role and uses in immunology 1 , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[60]  Elina Hyppönen,et al.  Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study , 2001, The Lancet.

[61]  Huub F. J. Savelkoul,et al.  1α,25-Dihydroxyvitamin D3 Has a Direct Effect on Naive CD4+ T Cells to Enhance the Development of Th2 Cells1 , 2001, The Journal of Immunology.

[62]  L. Adorini,et al.  Regulatory T Cells Induced by 1α,25-Dihydroxyvitamin D3 and Mycophenolate Mofetil Treatment Mediate Transplantation Tolerance1 , 2001, The Journal of Immunology.

[63]  B. Christensson,et al.  Downregulation of bactericidal peptides in enteric infections: A novel immune escape mechanism with bacterial DNA as a potential regulator , 2001, Nature Medicine.

[64]  L. Adorini,et al.  Regulatory T Cells Induced by 1 ,25-Dihydroxyvitamin D3 and Mycophenolate Mofetil Treatment Mediate Transplantation Tolerance , 2001 .

[65]  C. Mathieu,et al.  1alpha,25-dihydroxyvitamin D3 induces an autoantigen-specific T-helper 1/T-helper 2 immune shift in NOD mice immunized with GAD65 (p524-543). , 2000, Diabetes.

[66]  P. Allavena,et al.  Vitamin D3 Affects Differentiation, Maturation, and Function of Human Monocyte-Derived Dendritic Cells1 , 2000, The Journal of Immunology.

[67]  L. Adorini,et al.  1α,25-Dihydroxyvitamin D3 Inhibits Differentiation, Maturation, Activation, and Survival of Dendritic Cells Leading to Impaired Alloreactive T Cell Activation , 2000, The Journal of Immunology.

[68]  B. Hollis,et al.  Vitamin D vs broad spectrum phototherapy in the treatment of seasonal affective disorder. , 1999, The journal of nutrition, health & aging.

[69]  H. DeLuca,et al.  Current understanding of the molecular actions of vitamin D. , 1998, Physiological reviews.

[70]  T. Chen,et al.  Human prostate cells synthesize 1,25-dihydroxyvitamin D3 from 25-hydroxyvitamin D3. , 1998, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[71]  P. Galan,et al.  Prevalence of Vitamin D Insufficiency in an Adult Normal Population , 1997, Osteoporosis International.

[72]  Kenneth M. Murphy,et al.  Functional diversity of helper T lymphocytes , 1996, Nature.

[73]  H. Spiegelberg,et al.  Immunosuppressive actions of 1,25-dihydroxyvitamin D3: preferential inhibition of Th1 functions. , 1995, The Journal of nutrition.

[74]  R. Bouillon,et al.  Structure-function relationships in the vitamin D endocrine system. , 1995, Endocrine reviews.

[75]  D. Bikle,et al.  Vitamin D, calcium, and epidermal differentiation. , 1993, Endocrine reviews.

[76]  E. Ritz,et al.  1,25-dihydroxyvitamin D3 production and vitamin D3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages. , 1993, Blood.

[77]  H. Koeffler,et al.  25-Hydroxyvitamin D3 metabolism by lipopolysaccharide-stimulated normal human macrophages. , 1987, The Journal of clinical endocrinology and metabolism.

[78]  S. Manolagas,et al.  1 alpha,25-Dihydroxyvitamin D3-binding macromolecules in human B lymphocytes: effects on immunoglobulin production. , 1986, Journal of immunology.

[79]  G. Rook,et al.  Vitamin D3, gamma interferon, and control of proliferation of Mycobacterium tuberculosis by human monocytes. , 1986, Immunology.

[80]  J. Adams,et al.  1,25-Dihydroxyvitamin D3 suppresses human T helper/inducer lymphocyte activity in vitro. , 1985, Journal of immunology.

[81]  M. Fanger,et al.  Inhibition of T lymphocyte mitogenesis by 1,25-dihydroxyvitamin D3 (calcitriol). , 1984, The Journal of clinical investigation.

[82]  J. Adams,et al.  1 alpha,25-dihydroxyvitamin D3 suppresses proliferation and immunoglobulin production by normal human peripheral blood mononuclear cells. , 1984, The Journal of clinical investigation.

[83]  S. Krane,et al.  Specific high-affinity receptors for 1,25-dihydroxyvitamin D3 in human peripheral blood mononuclear cells: presence in monocytes and induction in T lymphocytes following activation. , 1983, The Journal of clinical endocrinology and metabolism.

[84]  J. Adams,et al.  Metabolism of 25-hydroxyvitamin D3 by cultured pulmonary alveolar macrophages in sarcoidosis. , 1983, The Journal of clinical investigation.

[85]  S. Manolagas,et al.  1,25-dihydroxyvitamin D3 receptors in human leukocytes. , 1983, Science.

[86]  A. Norman,et al.  Hypercalcemia in an anephric patient with sarcoidosis: evidence for extrarenal generation of 1,25-dihydroxyvitamin D. , 1981, The New England journal of medicine.

[87]  M. Haussler,et al.  Biochemical evidence for 1,25-dihydroxyvitamin D receptor macromolecules in parathyroid, pancreatic, pituitary, and placental tissues. , 1980, Life sciences.

[88]  T. Oppé,et al.  Vitamin D deficiency. , 1979, British medical journal.

[89]  W. C. Spackman.  Correspondence , 1921, The Indian medical gazette.