Future Perspectives and Challenges of Prostate MRI

Prostate cancer is a major cause of morbidity and mortality worldwide [1]. However, unlike other more aggressive cancers, such as lung and pancreatic cancer which are almost always aggressive, prostate cancers exhibit a broad range of biology ranging from indolent to highly aggressive. The term “clinically significant” prostate cancer has recently been introduced to distinguish those tumors likely to lead to death from those likely to be indolent which have no impact on survival [2, 3]. However, the line of demarcation between these two categories of prostate cancer remains unclear and in any given patient can vary.