Human memory CTL response specific for influenza A virus is broad and multispecific.

[1]  G Y Ishioka,et al.  Utilization of MHC class I transgenic mice for development of minigene DNA vaccines encoding multiple HLA-restricted CTL epitopes. , 1999, Journal of immunology.

[2]  J. Altman,et al.  Characteristics of virus-specific CD8(+) T cells in the liver during the control and resolution phases of influenza pneumonia. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[3]  John Cruz,et al.  Human Cytotoxic T-Lymphocyte Repertoire to Influenza A Viruses , 1998, Journal of Virology.

[4]  S. Rowland-Jones,et al.  Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. , 1998, The Journal of clinical investigation.

[5]  Alessandro Sette,et al.  Conserved T Cell Receptor Repertoire in Primary and Memory CD8 T Cell Responses to an Acute Viral Infection , 1998, The Journal of experimental medicine.

[6]  G. Ogg,et al.  Direct Visualization of Antigen-specific CD8+T Cells during the Primary Immune Response to Epstein-Barr Virus In Vivo , 1998, The Journal of experimental medicine.

[7]  D. Busch,et al.  MHC class I/peptide stability: implications for immunodominance, in vitro proliferation, and diversity of responding CTL. , 1998, Journal of immunology.

[8]  H. Grey,et al.  Pools of lipidated HTL-CTL constructs prime for multiple HBV and HCV CTL epitope responses. , 1998, Vaccine.

[9]  M A Nowak,et al.  Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA. , 1998, Science.

[10]  G. Ogg,et al.  Direct isolation, phenotyping and cloning of low-frequency antigen-specific cytotoxic T lymphocytes from peripheral blood , 1998, Current Biology.

[11]  D. Moss,et al.  Delivery of multiple CD8 cytotoxic T cell epitopes by DNA vaccination. , 1998, Journal of immunology.

[12]  J. Altman,et al.  Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. , 1998, Immunity.

[13]  J. Sidney,et al.  Derivation of HLA-A11/Kb transgenic mice: functional CTL repertoire and recognition of human A11-restricted CTL epitopes. , 1997, Journal of immunology.

[14]  A. McMichael,et al.  Rapid Effector Function in CD8+ Memory T Cells , 1997, The Journal of experimental medicine.

[15]  R W Chesnut,et al.  Human histocompatibility leukocyte antigen-binding supermotifs predict broadly cross-reactive cytotoxic T lymphocyte responses in patients with acute hepatitis. , 1997, The Journal of clinical investigation.

[16]  H. Grey,et al.  The hepatitis B virus-specific CTL responses induced in humans by lipopeptide vaccination are comparable to those elicited by acute viral infection. , 1997, Journal of immunology.

[17]  R W Chesnut,et al.  Degenerate cytotoxic T cell epitopes from P. falciparum restricted by multiple HLA-A and HLA-B supertype alleles. , 1997, Immunity.

[18]  A Sette,et al.  Two complementary methods for predicting peptides binding major histocompatibility complex molecules. , 1997, Journal of molecular biology.

[19]  J. Yewdell,et al.  MHC affinity, peptide liberation, T cell repertoire, and immunodominance all contribute to the paucity of MHC class I-restricted peptides recognized by antiviral CTL. , 1997, Journal of immunology.

[20]  A. Vitiello,et al.  Immunodominance analysis of CTL responses to influenza PR8 virus reveals two new dominant and subdominant Kb-restricted epitopes. , 1996, Journal of immunology.

[21]  J. Sidney,et al.  Analysis of cytotoxic T cell responses to dominant and subdominant epitopes during acute and chronic lymphocytic choriomeningitis virus infection. , 1996, Journal of immunology.

[22]  S. L. Silins,et al.  Development of Epstein-Barr virus-specific memory T cell receptor clonotypes in acute infectious mononucleosis , 1996, The Journal of experimental medicine.

[23]  M F del Guercio,et al.  Specificity and degeneracy in peptide binding to HLA-B7-like class I molecules. , 1996, Journal of immunology.

[24]  C. Rice,et al.  Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients , 1996, Journal of virology.

[25]  J. Manuguerra,et al.  Protection against lethal viral infection by vaccination with nonimmunodominant peptides. , 1996, Journal of immunology.

[26]  A Sette,et al.  Practical, biochemical and evolutionary implications of the discovery of HLA class I supermotifs. , 1996, Immunology today.

[27]  M F del Guercio,et al.  Definition of an HLA-A3-like supermotif demonstrates the overlapping peptide-binding repertoires of common HLA molecules. , 1996, Human immunology.

[28]  A. Vitiello,et al.  Differences and similarities in the A2.1‐restricted cytotoxic T cell repertoire in humans and human leukocyte antigen‐transgenic mice , 1996, European journal of immunology.

[29]  B. Walker,et al.  HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release. , 1995, The Journal of clinical investigation.

[30]  H. Grey,et al.  In vitro induction of primary, antigen-specific CTL from human peripheral blood mononuclear cells stimulated with synthetic peptides. , 1995, Molecular immunology.

[31]  V. Engelhard,et al.  Definition of a human T cell epitope from influenza A non-structural protein 1 using HLA-A2.1 transgenic mice. , 1995, International immunology.

[32]  B. Moss,et al.  The cytotoxic T lymphocyte response to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis , 1995, The Journal of experimental medicine.

[33]  J. Bell,et al.  Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment , 1995, The Journal of experimental medicine.

[34]  M F del Guercio,et al.  Several HLA alleles share overlapping peptide specificities. , 1995, Journal of immunology.

[35]  A. Vitiello,et al.  The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes. , 1994, Journal of immunology.

[36]  D. Margulies,et al.  Determinant selection of major histocompatibility complex class I- restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues , 1994, The Journal of experimental medicine.

[37]  J. Sidney,et al.  Peptide binding to the most frequent HLA-A class I alleles measured by quantitative molecular binding assays. , 1994, Molecular immunology.

[38]  A Sette,et al.  Definition of specific peptide motifs for four major HLA-A alleles. , 1994, Journal of immunology.

[39]  A Sette,et al.  Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins. , 1994, Journal of immunology.

[40]  N. Cox,et al.  An influenza A (H1N1) virus, closely related to swine influenza virus, responsible for a fatal case of human influenza , 1994, Journal of virology.

[41]  H. Grey,et al.  Induction of anti-tumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopes. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[42]  Günter J. Hämmerling,et al.  Selectivity of MHC-encoded peptide transporters from human, mouse and rat , 1994, Nature.

[43]  J. Yewdell,et al.  TAP (transporter associated with antigen processing)-independent presentation of endogenously synthesized peptides is enhanced by endoplasmic reticulum insertion sequences located at the amino- but not carboxyl-terminus of the peptide. , 1994, Journal of immunology.

[44]  K. Parker,et al.  Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains. , 1994, Journal of immunology.

[45]  K. Parker,et al.  HLA-A1 and HLA-A3 T cell epitopes derived from influenza virus proteins predicted from peptide binding motifs. , 1993, Journal of immunology.

[46]  J. Sidney,et al.  Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules , 1993, Cell.

[47]  R. Henderson,et al.  Characteristics of endogenous peptides eluted from the class I MHC molecule HLA-B7 determined by mass spectrometry and computer modeling. , 1993, Journal of immunology.

[48]  A. Vitiello,et al.  HLA A2 restricted cytotoxic T lymphocyte responses to multiple hepatitis B surface antigen epitopes during hepatitis B virus infection. , 1993, Journal of immunology.

[49]  A. Vitiello,et al.  Definition of a minimal optimal cytotoxic T-cell epitope within the hepatitis B virus nucleocapsid protein , 1993, Journal of virology.

[50]  G. Klein,et al.  An HLA-A11-specific motif in nonamer peptides derived from viral and cellular proteins. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[51]  M. Masucci,et al.  Multiple HLA A11-restricted cytotoxic T-lymphocyte epitopes of different immunogenicities in the Epstein-Barr virus-encoded nuclear antigen 4 , 1993, Journal of virology.

[52]  R. Moots,et al.  Identification of the nonamer peptide from influenza A matrix protein and the role of pockets of HLA‐A2 in its recognition by cytotoxic T lymphocytes , 1992, European journal of immunology.

[53]  M. Bednarek,et al.  The minimum peptide epitope from the influenza virus matrix protein. Extra and intracellular loading of HLA-A2. , 1991, Journal of immunology.

[54]  R. Zinkernagel,et al.  Major histocompatibility complex binding and T cell recognition of a viral nonapeptide containing a minimal tetrapeptide , 1991, European journal of immunology.

[55]  A. Vitiello,et al.  Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex , 1991, The Journal of experimental medicine.

[56]  J. Levy,et al.  In vitro human cytotoxic T cell responses against influenza A virus can be induced and selected by synthetic peptides , 1990, European journal of immunology.

[57]  F Gotch,et al.  Recognition of influenza A matrix protein by HLA-A2-restricted cytotoxic T lymphocytes. Use of analogues to orientate the matrix peptide in the HLA-A2 binding site , 1988, The Journal of experimental medicine.

[58]  B. Moss,et al.  Murine cytotoxic T lymphocyte recognition of individual influenza virus proteins. High frequency of nonresponder MHC class I alleles , 1988, The Journal of experimental medicine.

[59]  A. Moriarty,et al.  Hepatitis B synthetic immunogen comprised of nucleocapsid T-cell sites and an envelope B-cell epitope. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[60]  A Sette,et al.  The relation between major histocompatibility complex (MHC) restriction and the capacity of Ia to bind immunogenic peptides , 1987, Science.

[61]  B. Moss,et al.  Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes , 1987, The Journal of experimental medicine.

[62]  A. McMichael,et al.  The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides , 1986, Cell.

[63]  W G Laver,et al.  Molecular mechanisms of variation in influenza viruses , 1982, Nature.

[64]  F. Greenwood,et al.  THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY. , 1963, The Biochemical journal.

[65]  E. S. Robinson,et al.  Effect of Exposure to Low Temperatures on Diphtheria Toxin-Antitoxin Mixtures , 1924, The Journal of Immunology.

[66]  J. Yewdell,et al.  Mechanisms of exogenous antigen presentation by MHC class I molecules in vitro and in vivo: implications for generating CD8+ T cell responses to infectious agents, tumors, transplants, and vaccines. , 1999, Advances in immunology.

[67]  J. Miller,et al.  Discovering the origins of immunological competence. , 1999, Annual review of immunology.

[68]  R. Phillips,et al.  Escape of human immunodeficiency virus from immune control. , 1997, Annual review of immunology.

[69]  F. Chisari,et al.  Hepatitis B virus immunopathogenesis. , 1995, Annual review of immunology.

[70]  A. Miller,et al.  Dominance and crypticity of T cell antigenic determinants. , 1993, Annual review of immunology.

[71]  B. Murphy,et al.  The systemic and mucosal immune response of humans to influenza A virus. , 1989, Current topics in microbiology and immunology.