Enhancement of thymidine production in E. coli by eliminating repressors regulating the carbamoyl phosphate synthetase operon
暂无分享,去创建一个
[1] W. Jang,et al. High NADPH/NADP+ ratio improves thymidine production by a metabolically engineered Escherichia coli strain. , 2010, Journal of biotechnology.
[2] W. Jang,et al. Thymidine production by overexpressing NAD+ kinase in an Escherichia coli recombinant strain , 2009, Biotechnology Letters.
[3] W. Jang,et al. Fermentative Production of Thymidine by a Metabolically Engineered Escherichia coli Strain , 2009, Applied and Environmental Microbiology.
[4] C. Turnbough,et al. Regulation of Pyrimidine Biosynthetic Gene Expression in Bacteria: Repression without Repressors , 2008, Microbiology and Molecular Biology Reviews.
[5] A. Ishihama,et al. RutR is the uracil/thymine‐sensing master regulator of a set of genes for synthesis and degradation of pyrimidines , 2007, Molecular microbiology.
[6] Jung-Kul Lee,et al. Thymidine production by Corynebacterium ammoniagenes mutants , 2005 .
[7] D. Gigot,et al. Purine and pyrimidine-specific repression of the Escherichia coli carAB operon are functionally and structurally coupled. , 2004, Journal of molecular biology.
[8] Hyeon-Cheol Lee,et al. Overproduction of thymidine by recombinant Brevibacterium helvolum amplified with thymidine monophosphate phosphohydrolase gene from bacteriophage PBS2 , 2004, Biotechnology Letters.
[9] D. Gigot,et al. Integration Host Factor (IHF) modulates the expression of the pyrimidine-specific promoter of the carAB operons of Escherichia coli K12 and Salmonella typhimurium LT2 , 1993, Molecular and General Genetics MGG.
[10] P. Couvreur,et al. I. Arginine. , 2002, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[11] Shamim Ahmad,et al. Screening of microbes, isolation, genetic manipulation, and physiological optimization of Brevibacterium helvolum to produce and excrete thymidine and deoxyuridine in high concentrations. , 2000, The Journal of general and applied microbiology.
[12] B. Wanner,et al. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[13] K. Murphy,et al. PCR-mediated gene replacement in Escherichia coli. , 2000, Gene.
[14] D. Gigot,et al. pyrH-encoded UMP-kinase directly participates in pyrimidine-specific modulation of promoter activity in Escherichia coli. , 1998, Journal of molecular biology.
[15] N. Glansdorff,et al. The arginine repressor of Escherichia coli K-12 makes direct contacts to minor and major groove determinants of the operators. , 1998, Journal of molecular biology.
[16] C. Turnbough,et al. Regulation of carAB Expression inEscherichia coli Occurs in Part through UTP-Sensitive Reiterative Transcription , 1998, Journal of bacteriology.
[17] D. Gigot,et al. carP, involved in pyrimidine regulation of the Escherichia coli carbamoylphosphate synthetase operon encodes a sequence-specific DNA-binding protein identical to XerB and PepA, also required for resolution of ColEI multimers. , 1995, Journal of molecular biology.
[18] S. Tsen. Chemostat selection of Escherichia coli mutants secreting thymidine, cytosine, uracil, guanine, and thymine , 1994, Applied Microbiology and Biotechnology.
[19] Broder,et al. Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[20] N. Glansdorff,et al. DNA sequence of the carA gene and the control region of carAB: tandem promoters, respectively controlled by arginine and the pyrimidines, regulate the synthesis of carbamoyl-phosphate synthetase in Escherichia coli K-12. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[21] P. Stragier,et al. Multiple regulatory signals in the control region of the Escherichia coli carAB operon. , 1984, Proceedings of the National Academy of Sciences of the United States of America.