Lifestyle intervention programme for Indian women with history of gestational diabetes mellitus

Aim To evaluate the feasibility and potential effectiveness of a lifestyle intervention (diet and physical activity) among women with history of gestational diabetes mellitus (GDM), delivered by trained facilitators. Methods Fifty-six normoglycaemic or prediabetic women with prior GDM were recruited at mean of 17 months postpartum. Socio-demographic, medical and anthropometric data were collected. Six sessions on lifestyle modification were delivered in groups (total four groups, with 12–15 women in each group). Pre and post intervention (6 months) weight, body mass index (BMI), waist circumference, 75 g oral glucose tolerance test, blood pressure (BP) and lipid parameters were compared. Results The intervention was feasible, with 80% of women attending four or more sessions. Post-intervention analyses showed a significant mean reduction of 1.8 kg in weight, 0.6 kg/m2 in BMI and 2 cm in waist circumference. There was also a significant drop of 0.3 mmol/L in fasting plasma glucose, 0.9 mmol/L in 2 h post glucose load value of plasma glucose, 3.6 mmHg in systolic BP, and 0.15 mmol/L in triglyceride levels. Changes in total cholesterol, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol and diastolic BP were non-significant. Conclusions This study showed feasibility of the lifestyle intervention delivered in group sessions to women with prior gestational diabetes.

[1]  A. Naheed,et al.  A lifestyle intervention programme for the prevention of Type 2 diabetes mellitus among South Asian women with gestational diabetes mellitus [LIVING study]: protocol for a randomized trial , 2018, Diabetic medicine : a journal of the British Diabetic Association.

[2]  D. Prabhakaran,et al.  Conversion of gestational diabetes mellitus to future Type 2 diabetes mellitus and the predictive value of HbA1c in an Indian cohort , 2017, Diabetic medicine : a journal of the British Diabetic Association.

[3]  B. Duncan,et al.  Lifestyle INtervention for Diabetes prevention After pregnancy (LINDA-Brasil): study protocol for a multicenter randomized controlled trial , 2016, BMC Pregnancy and Childbirth.

[4]  R. Whittemore,et al.  Postpartum Lifestyle Interventions to Prevent Type 2 Diabetes Among Women with History of Gestational Diabetes: A Systematic Review of Randomized Clinical Trials. , 2016, Journal of women's health.

[5]  F. Bogossian,et al.  A review of interventions to prevent Type 2 Diabetes after Gestational Diabetes. , 2014, Women and birth : journal of the Australian College of Midwives.

[6]  R. Anjana,et al.  Clinical profile, outcomes, and progression to type 2 diabetes among Indian women with gestational diabetes mellitus seen at a diabetes center in south India , 2014, Indian journal of endocrinology and metabolism.

[7]  Sheri J. Hartman,et al.  Estudio Parto: postpartum diabetes prevention program for hispanic women with abnormal glucose tolerance in pregnancy: a randomised controlled trial – study protocol , 2014, BMC Pregnancy and Childbirth.

[8]  J. Newell,et al.  Reasons for participation and non-participation in a diabetes prevention trial among women with prior gestational diabetes mellitus (GDM) , 2014, BMC Medical Research Methodology.

[9]  T. Skinner,et al.  Mothers After Gestational Diabetes in Australia Diabetes Prevention Program (MAGDA-DPP) post-natal intervention: study protocol for a randomized controlled trial , 2013, Trials.

[10]  K. Chinna,et al.  Low glycaemic index diets improve glucose tolerance and body weight in women with previous history of gestational diabetes: a six months randomized trial , 2013, Nutrition Journal.

[11]  Xilin Yang,et al.  Tianjin Gestational Diabetes Mellitus Prevention Program: study design, methods, and 1-year interim report on the feasibility of lifestyle intervention program. , 2012, Diabetes research and clinical practice.

[12]  A. Hingorani,et al.  Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis , 2009, The Lancet.

[13]  C. Fall,et al.  Gestational diabetes and the incidence of diabetes in the 5 years following the index pregnancy in South Indian women , 2007, Diabetes research and clinical practice.

[14]  E. Vartiainen,et al.  Prevention of Type 2 Diabetes by lifestyle intervention in an Australian primary health care setting: Greater Green Triangle (GGT) Diabetes Prevention Project , 2007, BMC public health.

[15]  S. R. Kulkarni,et al.  High risk of diabetes and metabolic syndrome in Indian women with gestational diabetes mellitus , 2004, Diabetic medicine : a journal of the British Diabetic Association.

[16]  BOULIN,et al.  Classification and Diagnosis of Diabetes. , 2022, Primary care.

[17]  J. William Ahwood,et al.  CLASSIFICATION , 1931, Foundations of Familiar Language.

[18]  L. Chasan-Taber.  Lifestyle interventions to reduce risk of diabetes among women with prior gestational diabetes mellitus. , 2015, Best practice & research. Clinical obstetrics & gynaecology.

[19]  D. Williamson,et al.  How effective were lifestyle interventions in real-world settings that were modeled on the Diabetes Prevention Program? , 2012, Health affairs.

[20]  H. Hansen.  Who is at High Risk , 1990 .