Combining gene expression QTL mapping and phenotypic spectrum analysis to uncover gene regulatory relationships
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Yan Cui | Ramin Homayouni | Mi Zhou | Lai Wei | Lu Lu | Robert W. Williams | Dan Goldowitz | Lawrence M. Pfeffer | R. Homayouni | Lai Wei | Lu Lu | L. Pfeffer | Y. Cui | D. Goldowitz | J. Peirce | Lei Bao | Hao Chen | Lei Bao | Jeremy L. Peirce | Hongqiang Li | Hao Chen | Mi Zhou | Hongqiang Li | Yan Cui
[1] Zhirong Sun,et al. Identifying genes related to drug anticancer mechanisms using support vector machine , 2002, FEBS letters.
[2] G. Baier,et al. Protein kinase Cepsilon is dispensable for TCR/CD3-signaling. , 2005, Molecular immunology.
[3] Andrew I Su,et al. Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics' , 2005, Nature Genetics.
[4] Albert-László Barabási,et al. Genetic Dissection of Transcriptional Regulation in Budding Yeast , 2002 .
[5] E. Schadt,et al. Genetic inheritance of gene expression in human cell lines. , 2004, American journal of human genetics.
[6] N. Wu,et al. PKCϵ Is a Unique Regulator for hsp90β Gene in Heat Shock Response* , 2003, Journal of Biological Chemistry.
[7] Yan Cui,et al. Integrative genetic analysis of transcription modules: towards filling the gap between genetic loci and inherited traits. , 2006, Human molecular genetics.
[8] J. Zhu,et al. An integrative genomics approach to the reconstruction of gene networks in segregating populations , 2004, Cytogenetic and Genome Research.
[9] L. McIntyre,et al. Combining mapping and arraying: An approach to candidate gene identification , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[10] E E Schadt,et al. Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits , 2005, Nature Genetics.
[11] P. Stenson,et al. Human Gene Mutation Database (HGMD , 2003 .
[12] K. Manly,et al. Map Manager QTX, cross-platform software for genetic mapping , 2001, Mammalian Genome.
[13] M. Goldman,et al. Protein kinase C epsilon: a new target to control inflammation and immune-mediated disorders. , 2004, The international journal of biochemistry & cell biology.
[14] J. Levine,et al. A novel nociceptor signaling pathway revealed in protein kinase C epsilon mutant mice. , 1999, Neuron.
[15] Hans Lehrach,et al. Functional Annotation of Mouse Genome Sequences , 2001, Science.
[16] Yan Cui,et al. Inferring gene transcriptional modulatory relations: a genetical genomics approach. , 2005, Human molecular genetics.
[17] J. Snapper,et al. Anti sense DNA down-regulates proteins kinase C-epsilon and enhances vasopressin-stimulated Na+ absorption in rabbit cortical collecting duct. , 1995, The Journal of clinical investigation.
[18] P. Ping,et al. PKCepsilon activation augments cardiac mitochondrial respiratory post-anoxic reserve--a putative mechanism in PKCepsilon cardioprotection. , 2005, Journal of molecular and cellular cardiology.
[19] Frederick P. Roth,et al. Predicting phenotype from patterns of annotation , 2003, ISMB.
[20] John D. Storey,et al. Multiple Locus Linkage Analysis of Genomewide Expression in Yeast , 2005, PLoS biology.
[21] Richard G. Jenner,et al. Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[22] N. Bing,et al. Genetical Genomics Analysis of a Yeast Segregant Population for Transcription Network Inference , 2005, Genetics.
[23] Alexander E. Kel,et al. MATCHTM: a tool for searching transcription factor binding sites in DNA sequences , 2003, Nucleic Acids Res..
[24] Carole A. Goble,et al. Investigating Semantic Similarity Measures Across the Gene Ontology: The Relationship Between Sequence and Annotation , 2003, Bioinform..
[25] Lu Lu,et al. The genetic structure of recombinant inbred mice: High-resolution consensus maps for complex trait analysis , 2001, Genome Biology.
[26] Marc Montminy,et al. Transcriptional regulation by the phosphorylation-dependent factor CREB , 2001, Nature Reviews Molecular Cell Biology.
[27] N. Katsanis,et al. Human genetics and disease: Beyond Mendel: an evolving view of human genetic disease transmission , 2002, Nature Reviews Genetics.
[28] C. Haley,et al. The genetic dissection of immune response using gene-expression studies and genome mapping. , 2005, Veterinary Immunology and Immunopathology.
[29] P. Ping,et al. PKCε activation augments cardiac mitochondrial respiratory post-anoxic reserve—a putative mechanism in PKCε cardioprotection , 2005 .
[30] John M. Hancock,et al. Building Mouse Phenotype Ontologies , 2003, Pacific Symposium on Biocomputing.
[31] T. Johnson,et al. Towards the cloning of genes underlying murine QTLs , 1998, Mammalian Genome.
[32] Cynthia L. Smith,et al. The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information , 2004, Genome Biology.
[33] John D. Storey,et al. Genetic interactions between polymorphisms that affect gene expression in yeast , 2005, Nature.
[34] Richard J. Mural,et al. Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[35] A. Shaywitz,et al. CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. , 1999, Annual review of biochemistry.
[36] E. Petretto,et al. Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease , 2005, Nature Genetics.
[37] P. Stenson,et al. Human Gene Mutation Database (HGMD®): 2003 update , 2003, Human mutation.
[38] Eric E Schadt,et al. Cis-acting expression quantitative trait loci in mice. , 2005, Genome research.
[39] Margit Burmeister,et al. Genetical genomics: combining genetics with gene expression analysis. , 2005, Human molecular genetics.
[40] C. Molony,et al. Genetic analysis of genome-wide variation in human gene expression , 2004, Nature.
[41] J. Naylor,et al. Mendelian inheritance in man: A catalog of human genes and genetic disorders , 1996 .
[42] Wolfgang Wurst,et al. A public gene trap resource for mouse functional genomics , 2004, Nature Genetics.
[43] R. Doerge,et al. Empirical threshold values for quantitative trait mapping. , 1994, Genetics.
[44] Marc Vidal,et al. Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis , 2005, Nature.
[45] Amanda Clare,et al. Machine learning of functional class from phenotype data , 2002, Bioinform..
[46] E. Wingender,et al. MATCH: A tool for searching transcription factor binding sites in DNA sequences. , 2003, Nucleic acids research.
[47] Lu Lu,et al. The genetic structure of recombinant inbred mice: high-resolution consensus maps for complex trait analysis , 2001, Genome Biology.
[48] D Siegmund,et al. Statistical methods for mapping quantitative trait loci from a dense set of markers. , 1999, Genetics.
[49] David BotsteinS’B. Mapping Mendelian Factors Underlying Quantitative Traits Using RFLP Linkage Maps , 2002 .
[50] Terence P. Speed,et al. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias , 2003, Bioinform..
[51] C. Haley,et al. Genetical genomics in humans and model organisms. , 2005, Trends in genetics : TIG.
[52] R. Stoughton,et al. Genetics of gene expression surveyed in maize, mouse and man , 2003, Nature.
[53] Leonid Kruglyak,et al. Local Regulatory Variation in Saccharomyces cerevisiae , 2005, PLoS genetics.
[54] Rachel B. Brem,et al. The landscape of genetic complexity across 5,700 gene expression traits in yeast. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[55] J. Levine,et al. A Novel Nociceptor Signaling Pathway Revealed in Protein Kinase C ε Mutant Mice , 1999, Neuron.
[56] J. Castle,et al. An integrative genomics approach to infer causal associations between gene expression and disease , 2005, Nature Genetics.
[57] J. Levine,et al. Chronic hyperalgesic priming in the rat involves a novel interaction between cAMP and PKCɛ second messenger pathways , 2005, Pain.
[58] A. Lichanska. Predicting drug sensitivity , 2001, Genome Biology.
[59] J. Nap,et al. Genetical genomics: the added value from segregation. , 2001, Trends in genetics : TIG.
[60] A. Raghunath,et al. Protein kinase Cepsilon actin-binding site is important for neurite outgrowth during neuronal differentiation. , 2002, Molecular biology of the cell.
[61] Jie Huang,et al. Proteolytic Activation of Protein Kinase C-ε by Caspase-mediated Processing and Transduction of Antiapoptotic Signals* , 2002, The Journal of Biological Chemistry.
[62] Rachel B. Brem,et al. Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors , 2003, Nature Genetics.
[63] Francis D. Gibbons,et al. Predicting protein complex membership using probabilistic network reliability. , 2004, Genome research.
[64] R. Sederoff,et al. Coordinated Genetic Regulation of Growth and Lignin Revealed by Quantitative Trait Locus Analysis of cDNA Microarray Data in an Interspecific Backcross of Eucalyptus1 , 2004, Plant Physiology.
[65] Tom H. Pringle,et al. The human genome browser at UCSC. , 2002, Genome research.
[66] Robert W. Williams,et al. Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function , 2005, Nature Genetics.
[67] V. McKusick. Mendelian inheritance in man , 1971 .