GILZ promotes production of peripherally induced Treg cells and mediates the crosstalk between glucocorticoids and TGF-β signaling.
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C. Riccardi | Michele Biagioli | S. Bruscoli | D. Sorcini | T. Frammartino | M. Cimino | O. Bereshchenko | Maddalena Coppo | A. Venanzi | Moises Di Sante | Tiziana Frammartino | Alessandra Venanzi
[1] J. Cidlowski,et al. Glucocorticoid receptor signaling in health and disease. , 2013, Trends in pharmacological sciences.
[2] W. Garrett,et al. The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis , 2013, Science.
[3] Susan M. Schlenner,et al. A late IL-33 response after exposure to Schistosoma haematobium antigen is associated with an up-regulation of IL-13 in human eosinophils , 2013, Parasite immunology.
[4] J. Bluestone,et al. Peripherally Induced Tregs – Role in Immune Homeostasis and Autoimmunity , 2013, Front. Immunol..
[5] A. Regev,et al. Dynamic regulatory network controlling Th17 cell differentiation , 2013, Nature.
[6] Daniel J. Kuster,et al. Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo , 2012, The Journal of experimental medicine.
[7] J. Weiss,et al. Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells , 2012, The Journal of experimental medicine.
[8] G. Schiechl,et al. Deletion of Foxp3+ regulatory T cells in genetically targeted mice supports development of intestinal inflammation , 2012, BMC Gastroenterology.
[9] A. Rudensky,et al. Extrathymic Generation of Regulatory T Cells in Placental Mammals Mitigates Maternal-Fetal Conflict , 2012, Cell.
[10] H. Liu,et al. Function of regulatory T-cells improved by dexamethasone in Graves' disease. , 2012, European journal of endocrinology.
[11] A. Rudensky,et al. Regulatory T cells: mechanisms of differentiation and function. , 2012, Annual review of immunology.
[12] A. Rudensky,et al. Extrathymically generated regulatory T cells control mucosal TH2 inflammation , 2012, Nature.
[13] Y. Wan,et al. Requirements of transcription factor Smad-dependent and -independent TGF-β signaling to control discrete T-cell functions , 2012, Proceedings of the National Academy of Sciences.
[14] C. Riccardi,et al. Long Glucocorticoid-induced Leucine Zipper (L-GILZ) Protein Interacts with Ras Protein Pathway and Contributes to Spermatogenesis Control* , 2011, The Journal of Biological Chemistry.
[15] T. Chatila,et al. A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity. , 2011, Immunity.
[16] C. Gutiérrez,et al. Dexamethasone upregulates FOXP3 expression without increasing regulatory activity. , 2011, Immunobiology.
[17] K. Honda,et al. Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species , 2011, Science.
[18] R. Morita,et al. Correction: Smad2 and Smad3 Are Redundantly Essential for the TGF-β–Mediated Regulation of Regulatory T Plasticity and Th1 Development , 2011, The Journal of Immunology.
[19] C. Stuelten,et al. Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I. , 2010, Immunity.
[20] R. Morita,et al. Smad2 and Smad3 Are Redundantly Essential for the TGF-β–Mediated Regulation of Regulatory T Plasticity and Th1 Development , 2010, The Journal of Immunology.
[21] A. Rudensky,et al. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate , 2010, Nature.
[22] C. Riccardi,et al. Glucocorticoid-induced Leucine Zipper (GILZ) and Long GILZ Inhibit Myogenic Differentiation and Mediate Anti-myogenic Effects of Glucocorticoids* , 2010, The Journal of Biological Chemistry.
[23] K. Kretschmer,et al. Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines , 2009, The Journal of experimental medicine.
[24] C. Benoist,et al. Foxp3+ regulatory T cells: differentiation, specification, subphenotypes , 2009, Nature Immunology.
[25] M. A. Curotto de Lafaille,et al. Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor? , 2009, Immunity.
[26] T. Chatila,et al. A Central Role for Induced Regulatory T Cells in Tolerance Induction in Experimental Colitis1 , 2009, The Journal of Immunology.
[27] E. Mazzon,et al. Glucocorticoid-induced leucine zipper is protective in Th1-mediated models of colitis. , 2009, Gastroenterology.
[28] Y. Belkaid,et al. T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance , 2008, Nature.
[29] R. Flavell,et al. TGF-β: A Master of All T Cell Trades , 2008, Cell.
[30] K. Furuuchi,et al. Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer , 2008, Nature Immunology.
[31] C. Ruan,et al. Circulating dendritic cells subsets and CD4+Foxp3+ regulatory T cells in adult patients with chronic ITP before and after treatment with high‐dose dexamethasome , 2007, European journal of haematology.
[32] Y. Belkaid,et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism , 2007, The Journal of experimental medicine.
[33] Y. Belkaid,et al. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid , 2007, The Journal of experimental medicine.
[34] A. Rudensky,et al. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice , 2007, Nature Immunology.
[35] J. Ortaldo,et al. Glucocorticoid amplifies IL‐2‐dependent expansion of functional FoxP3+CD4+CD25+ T regulatory cells in vivo and enhances their capacity to suppress EAE , 2006, European journal of immunology.
[36] C. Gutiérrez,et al. Enrichment of CD4+ CD25high T cell population in patients with systemic lupus erythematosus treated with glucocorticoids , 2006, Annals of the rheumatic diseases.
[37] E. Mazzon,et al. Increased GILZ expression in transgenic mice up-regulates Th-2 lymphokines. , 2006, Blood.
[38] T. Brunner,et al. Intestinal Epithelial Cells Synthesize Glucocorticoids and Regulate T Cell Activation , 2004, The Journal of experimental medicine.
[39] C. Riccardi,et al. Decrease of Bcl-xL and augmentation of thymocyte apoptosis in GILZ overexpressing transgenic mice. , 2004, Blood.
[40] C. Akdis,et al. Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma. , 2004, The Journal of allergy and clinical immunology.
[41] N. Hassanein,et al. Effects of IL-7 and dexamethasone: induction of CD25, the high affinity IL-2 receptor, on human CD4+ cells. , 2004, Cellular immunology.
[42] Xin Chen,et al. Differential response of murine CD4+CD25+ and CD4+CD25– T cells to dexamethasone‐induced cell death , 2004, European journal of immunology.
[43] D. Klatzmann,et al. Continuous Activation of Autoreactive CD4+ CD25+ Regulatory T Cells in the Steady State , 2003, The Journal of experimental medicine.
[44] Wei Gu,et al. Acetylation inactivates the transcriptional repressor BCL6 , 2002, Nature Genetics.
[45] David F. Richards,et al. In Vitro Generation of Interleukin 10–producing Regulatory CD4+ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines , 2002, The Journal of experimental medicine.
[46] C. Riccardi,et al. Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB. , 2001, Blood.
[47] A. Zinsmeister,et al. The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study. , 2001, Gastroenterology.
[48] C. Riccardi,et al. A new dexamethasone-induced gene of the leucine zipper family protects T lymphocytes from TCR/CD3-activated cell death. , 1997, Immunity.
[49] R. Coffman,et al. Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. , 1993, International immunology.
[50] S. Barry,et al. Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease , 2009, Journal of Clinical Immunology.