Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility
暂无分享,去创建一个
H. Höfler | W. Birchmeier | P. Hutzler | B. Luber | K. Becker | C. Schott | U. Reich | G. Handschuh | S. Candidus | Sandra Oswald | Helma Becke
[1] W. Birchmeier,et al. Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. , 1998, Science.
[2] Anthony E. Reeve,et al. E-cadherin germline mutations in familial gastric cancer , 1998, Nature.
[3] Akira Kikuchi,et al. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK‐3β and β‐catenin and promotes GSK‐3β‐dependent phosphorylation of β‐catenin , 1998 .
[4] A. Hall,et al. Rho GTPases and the actin cytoskeleton. , 1998, Science.
[5] W. Birchmeier,et al. Role of morphogenetic factors in metastasis of mammary carcinoma cells , 1998, Oncogene.
[6] M. Ikura,et al. Lateral self‐assembly of E‐cadherin directed by cooperative calcium binding , 1997, FEBS letters.
[7] A. Hall,et al. The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts , 1997, The Journal of cell biology.
[8] S. Nishizuka,et al. Inactivation of the E‐Cadherin Gene in Primary Gastric Carcinomas and Gastric Carcinoma Cell Lines , 1996, Japanese journal of cancer research : Gann.
[9] B. Herrmann,et al. Nuclear localization of β-catenin by interaction with transcription factor LEF-1 , 1996, Mechanisms of Development.
[10] Michael Kühl,et al. Functional interaction of β-catenin with the transcription factor LEF-1 , 1996, Nature.
[11] Hans Clevers,et al. XTcf-3 Transcription Factor Mediates β-Catenin-Induced Axis Formation in Xenopus Embryos , 1996, Cell.
[12] S. Hirohashi,et al. E‐Cadherin Gene Mutations in Signet Ring Cell Carcinoma of the Stomach , 1996, Japanese journal of cancer research : Gann.
[13] W. Birchmeier,et al. Prognostic value of E‐cadherin expression in 413 gastric carcinomas , 1996, International journal of cancer.
[14] M. Ikura,et al. Structural basis of calcium-induced E-cadherin rigidification and dimerization , 1996, Nature.
[15] T. Mitchison,et al. Actin-Based Cell Motility and Cell Locomotion , 1996, Cell.
[16] D. Lauffenburger,et al. Cell Migration: A Physically Integrated Molecular Process , 1996, Cell.
[17] A. Ochiai,et al. Simultaneous expression of cadherin-11 in signet-ring cell carcinoma and stromal cells of diffuse-type gastric cancer. , 1996, Cancer letters.
[18] S. Zigmond,et al. Signal transduction and actin filament organization. , 1996, Current opinion in cell biology.
[19] A. Watanabe,et al. Clinicopathologic evaluation of immunohistochemical E‐cadherin expression in human gastric carcinomas , 1995, Cancer.
[20] J. Gordon,et al. Inflammatory Bowel Disease and Adenomas in Mice Expressing a Dominant Negative N-Cadherin , 1995, Science.
[21] D L Rimm,et al. Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[22] A. P. Soler,et al. Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin , 1995, The Journal of cell biology.
[23] F. Molemans,et al. Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1). , 1995, Genomics.
[24] M. Ikura,et al. Solution structure of the epithelial cadherin domain responsible for selective cell adhesion , 1995, Science.
[25] W. Birchmeier,et al. E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton , 1994, The Journal of cell biology.
[26] N. Lemoine,et al. Loss of membranous E‐cadherin expression in pancreatic cancer: Correlation with lymph node metastasis, high grade, and advanced stage , 1994, The Journal of pathology.
[27] S. Hirohashi,et al. Point Mutation of the E–Cadherin Gene in Invasive Lobular Carcinoma of the Breast , 1994, Japanese journal of cancer research : Gann.
[28] S. Ishihara,et al. The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules , 1994, The Journal of cell biology.
[29] J. Engel,et al. Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium binding. , 1994, European journal of biochemistry.
[30] H. Höfler,et al. E-cadherin gene mutations provide clues to diffuse type gastric carcinomas. , 1994, Cancer research.
[31] W J Nelson,et al. Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells , 1994, The Journal of cell biology.
[32] W. Birchmeier,et al. Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness. , 1994, Biochimica et biophysica acta.
[33] A. Berchuck,et al. Mutations of the E–cadherin gene in human gynecologic cancers , 1994, Nature Genetics.
[34] S. Hirohashi,et al. Frequent Loss of α Catenin Expression in Scirrhous Carcinomas with Scattered Cell Growth , 1994, Japanese journal of cancer research : Gann.
[35] S. Hirohashi,et al. E-cadherin gene mutations in human gastric carcinoma cell lines. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[36] F. Masiarz,et al. Association of the APC gene product with beta-catenin. , 1993, Science.
[37] K. Kinzler,et al. Association of the APC tumor suppressor protein with catenins. , 1993, Science.
[38] M. Takeichi. Cadherins in cancer: implications for invasion and metastasis. , 1993, Current opinion in cell biology.
[39] R. Kemler. From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. , 1993, Trends in genetics : TIG.
[40] H. Höfler,et al. Exon skipping in the E-cadherin gene transcript in metastatic human gastric carcinomas. , 1993, Human molecular genetics.
[41] W. Birchmeier,et al. E-cadherin expression in primary and metastatic gastric cancer: down-regulation correlates with cellular dedifferentiation and glandular disintegration. , 1993, Cancer research.
[42] B. Vogelstein,et al. Cell adhesion molecules as tumour suppressors. , 1993, Trends in cell biology.
[43] W. Birchmeier,et al. A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[44] C. Kintner. Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain , 1992, Cell.
[45] Kathleen A. Krzeminski,et al. Remodeling the cell surface distribution of membrane proteins during the development of epithelial cell polarity , 1992, The Journal of cell biology.
[46] M. Quintanilla,et al. A role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis , 1991, The Journal of cell biology.
[47] W. Birchmeier,et al. E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells , 1991, The Journal of cell biology.
[48] B. Zetter,et al. In vitro and in vivo consequences of VLA-2 expression on rhabdomyosarcoma cells. , 1991, Science.
[49] M. Takeichi,et al. Cadherin cell adhesion receptors as a morphogenetic regulator. , 1991, Science.
[50] J. Engel,et al. Single amino acid substitutions in one Ca2+ binding site of uvomorulin abolish the adhesive function , 1990, Cell.
[51] R. Kemler,et al. Correct proteolytic cleavage is required for the cell adhesive function of uvomorulin , 1990, The Journal of cell biology.
[52] M. Ringwald,et al. Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[53] L. Romer,et al. EndoCAM: a novel endothelial cell-cell adhesion molecule , 1990, The Journal of cell biology.
[54] J. Thiery,et al. Rearrangements of desmosomal and cytoskeletal proteins during the transition from epithelial to fibroblastoid organization in cultured rat bladder carcinoma cells , 1989, The Journal of cell biology.
[55] M. Takeichi,et al. Cell binding function of E‐cadherin is regulated by the cytoplasmic domain. , 1988, The EMBO journal.
[56] Akinao Nose,et al. Expressed recombinant cadherins mediate cell sorting in model systems , 1988, Cell.
[57] K. Yasuda,et al. Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA , 1987, Nature.
[58] G. Edelman,et al. Linear organization of the liver cell adhesion molecule L-CAM. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[59] P. Laurén,et al. THE TWO HISTOLOGICAL MAIN TYPES OF GASTRIC CARCINOMA: DIFFUSE AND SO-CALLED INTESTINAL-TYPE CARCINOMA. AN ATTEMPT AT A HISTO-CLINICAL CLASSIFICATION. , 1965, Acta pathologica et microbiologica Scandinavica.
[60] H. Barr,et al. Altered cadherin and catenin complexes in the Barrett's esophagus-dysplasia-adenocarcinoma sequence: correlation with disease progression and dedifferentiation. , 1998, The American journal of pathology.
[61] H. Höfler,et al. No Evidence for Mutations in the α- and β-Catenin Genes in Human Gastric and Breast Carcinomas , 1996 .
[62] E. Hay. An overview of epithelio-mesenchymal transformation. , 1995, Acta anatomica.
[63] M. Takeichi,et al. Disruption of epithelial cell-cell adhesion by exogenous expression of a mutated nonfunctional N-cadherin. , 1993, Molecular biology of the cell.
[64] W. Birchmeier,et al. The role of E-cadherin and scatter factor in tumor invasion and cell motility. , 1991, EXS.
[65] A. Murray,et al. In situ embedding of cell monolayers cultured on plastic surfaces for electron microscopy. , 1991, Biotechnic & histochemistry : official publication of the Biological Stain Commission.