Die Wertigkeit der Echtzeitelastographie in der Diagnostik des Prostatakarzinoms

ZusammenfassungRandomisierte Biopsien unter transrektalem Ultraschall sind der goldene Standard in der Prostatakarzinomdiagnostik. Mit dem technischen Fortschritt sowohl in der konventionellen B-Bild-Ultraschallqualität als auch durch den Einsatz neuerer komplementärer Methoden zum transrektalen Ultraschall eröffnen sich in der Diagnostik neue Möglichkeiten hinsichtlich einer möglichen früheren und gezielteren Diagnostik. Eine dieser Methoden stellt die ultraschallbasierte Echtzeitelastographie dar, deren Stellenwert noch nicht gänzlich geklärt ist, die Ansätze jedoch viel versprechend erscheinen. Die Anzahl der Publikationen deuten auf ein wachsendes Interesse an diese Technik und deren Einsatz hin.AbstractRandomized biopsy sampling under transrectal ultrasound (TRUS) guidance is the gold standard for the diagnosis of prostate cancer. In addition improvements in the quality of conventional ultrasound, new methods that complement conventional TRUS are opening the door to earlier and better targeted diagnosis of prostate cancer. One of these new methods is sonoelastography. Its impact on prostate cancer diagnostics has not yet been fully investigated, but the number of publications on this new technique indicate increasing interest in it.

[1]  H. Ermert,et al.  [Impact of elastography in clinical diagnosis of prostate cancer. A comparison of cancer detection between B-mode sonography and elastography-guided 10-core biopsies]. , 2008, Der Urologe. Ausg. A.

[2]  T. Krouskop,et al.  Elastic Moduli of Breast and Prostate Tissues under Compression , 1998, Ultrasonic imaging.

[3]  H. Frey [Realtime elastography. A new ultrasound procedure for the reconstruction of tissue elasticity]. , 2003, Der Radiologe.

[4]  G. Bartsch,et al.  Comparison of sonoelastography guided biopsy with systematic biopsy: impact on prostate cancer detection , 2007, European Radiology.

[5]  T. Schlomm,et al.  Evaluation of prostate cancer detection with ultrasound real-time elastography: a comparison with step section pathological analysis after radical prostatectomy. , 2008, European urology.

[6]  Alexandre Pelzer,et al.  Ultrasound of prostate cancer: recent advances , 2008, European Radiology.

[7]  J. Ophir,et al.  Elastography: A Quantitative Method for Imaging the Elasticity of Biological Tissues , 1991, Ultrasonic imaging.

[8]  W. Horninger,et al.  Contrast‐enhanced ultrasonography using cadence‐contrast pulse sequencing technology for targeted biopsy of the prostate , 2009, BJU international.

[9]  Tsuyoshi Shiina,et al.  The impact of real-time tissue elasticity imaging (elastography) on the detection of prostate cancer: clinicopathological analysis , 2007, International Journal of Clinical Oncology.

[10]  Helmut Ermert,et al.  Initial experiences with real-time elastography guided biopsies of the prostate. , 2005, The Journal of urology.

[11]  Hui Zhi,et al.  Semi-quantitating stiffness of breast solid lesions in ultrasonic elastography. , 2008, Academic radiology.

[12]  H. Ermert,et al.  Stellenwert der Elastographie in der klinischen Diagnostik des lokalisierten Prostatakarzinoms , 2008, Der Urologe.

[13]  M. Sumura,et al.  Initial evaluation of prostate cancer with real‐time elastography based on step‐section pathologic analysis after radical prostatectomy: A preliminary study , 2007, International journal of urology : official journal of the Japanese Urological Association.

[14]  G. Bartsch,et al.  Real‐time elastography for detecting prostate cancer: preliminary experience , 2007, BJU international.

[15]  T. Loch Computerized transrectal ultrasound (C-TRUS) of the prostate: detection of cancer in patients with multiple negative systematic random biopsies , 2007, World Journal of Urology.

[16]  Johan Braeckman,et al.  Computer‐aided ultrasonography (HistoScanning): a novel technology for locating and characterizing prostate cancer , 2008, BJU international.