Long non-coding RNAs control hematopoietic stem cell function.

[1]  R. Eils,et al.  Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis. , 2014, Cell stem cell.

[2]  B. Göttgens,et al.  Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. , 2014, Cell stem cell.

[3]  Ross C Hardison,et al.  Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development. , 2014, Blood.

[4]  H. Lodish,et al.  Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation. , 2014, Blood.

[5]  Wei Li,et al.  Large conserved domains of low DNA methylation maintained by Dnmt3a , 2013, Nature Genetics.

[6]  Xi C. He,et al.  Maternal imprinting at the H19–Igf2 locus maintains adult haematopoietic stem cell quiescence , 2013, Nature.

[7]  E. Lander,et al.  The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome , 2013, Science.

[8]  M. Goodell,et al.  Perspectives and future directions for epigenetics in hematology. , 2013, Blood.

[9]  H. Lodish,et al.  Zfp36l2 is required for self-renewal of early erythroid BFU-E progenitors , 2013, Nature.

[10]  Zev N. Kronenberg,et al.  Transposable Elements Are Major Contributors to the Origin, Diversification, and Regulation of Vertebrate Long Noncoding RNAs , 2013, PLoS genetics.

[11]  Eda Yildirim,et al.  Xist RNA Is a Potent Suppressor of Hematologic Cancer in Mice , 2013, Cell.

[12]  David A. Orlando,et al.  Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells , 2013, Proceedings of the National Academy of Sciences.

[13]  Vincent L. Butty,et al.  Braveheart, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment , 2013, Cell.

[14]  J. Kocher,et al.  CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model , 2013, Nucleic acids research.

[15]  Gary D Bader,et al.  Attenuation of miR-126 Activity Expands HSC In Vivo without Exhaustion , 2012, Cell stem cell.

[16]  Benjamin Dartigues,et al.  Novel roles for KLF1 in erythropoiesis revealed by mRNA-seq , 2012, Genome research.

[17]  G. Natoli,et al.  Noncoding transcription at enhancers: general principles and functional models. , 2012, Annual review of genetics.

[18]  David R. Kelley,et al.  Transposable elements reveal a stem cell-specific class of long noncoding RNAs , 2012, Genome Biology.

[19]  Nathan C Boles,et al.  Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice. , 2012, Cell stem cell.

[20]  David G. Knowles,et al.  The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression , 2012, Genome research.

[21]  J. Rinn,et al.  Modular regulatory principles of large non-coding RNAs , 2012, Nature.

[22]  D. Bartel,et al.  Conserved Function of lincRNAs in Vertebrate Embryonic Development despite Rapid Sequence Evolution , 2011, Cell.

[23]  H. Lodish,et al.  Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation. , 2011, Genes & development.

[24]  Brad A Chapman,et al.  The genomic binding sites of a noncoding RNA , 2011, Proceedings of the National Academy of Sciences.

[25]  J. Berg,et al.  Dnmt3a is essential for hematopoietic stem cell differentiation , 2011, Nature Genetics.

[26]  Howard Y. Chang,et al.  Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. , 2011, Molecular cell.

[27]  O. Abdel-Wahab,et al.  Faculty Opinions recommendation of lincRNAs act in the circuitry controlling pluripotency and differentiation. , 2011 .

[28]  Brian P. Brunk,et al.  Comparative analysis of RNA-Seq alignment algorithms and the RNA-Seq unified mapper (RUM) , 2011, Bioinform..

[29]  John T. Wei,et al.  Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression , 2011, Nature Biotechnology.

[30]  Howard Y. Chang,et al.  Extensive and coordinated transcription of noncoding RNAs within cell cycle promoters , 2011, Nature Genetics.

[31]  Anagha Joshi,et al.  A compendium of genome-wide hematopoietic transcription factor maps supports the identification of gene regulatory control mechanisms. , 2011, Experimental hematology.

[32]  Yong-mei Zhu,et al.  Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia , 2011, Nature Genetics.

[33]  Joshua F. McMichael,et al.  DNMT3A mutations in acute myeloid leukemia. , 2010, The New England journal of medicine.

[34]  H. Mitsuya,et al.  Mutation in the RNA binding protein TIS11D/ZFP36L2 is associated with the pathogenesis of acute leukemia. , 2010, International journal of oncology.

[35]  Aadel A. Chaudhuri,et al.  MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output , 2010, Proceedings of the National Academy of Sciences.

[36]  S. Salzberg,et al.  NIH Public Access Author Manuscript , 2006 .

[37]  M. Gerstein,et al.  A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster. , 2009, Blood.

[38]  Elinore M Mercer,et al.  E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors , 2009, Proceedings of the National Academy of Sciences.

[39]  E. Richfield,et al.  Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis. , 2008, Blood.

[40]  Yasuo Ikeda,et al.  PML targeting eradicates quiescent leukaemia-initiating cells , 2008, Nature.

[41]  Aadel A. Chaudhuri,et al.  Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder , 2008, The Journal of experimental medicine.

[42]  Steven B. Bradfute,et al.  Hematopoietic fingerprints: an expression database of stem cells and their progeny. , 2007, Cell stem cell.

[43]  R. Weiss,et al.  EGO, a novel, noncoding RNA gene, regulates eosinophil granule protein transcript expression. , 2007, Blood.

[44]  S. Schurmans,et al.  Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development , 2003, Nature Immunology.

[45]  L. Carlsson,et al.  Hematopoietic progenitor/stem cells immortalized by Lhx2 generate functional hematopoietic cells in vivo. , 2002, Blood.

[46]  A. S. Conner,et al.  Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo , 1996, The Journal of experimental medicine.

[47]  M. Mancini,et al.  Characterization of a recurrent translocation t(2;3)(p15–22;q26) occurring in acute myeloid leukaemia , 2006, Leukemia.