Porcine hematopoietic cell xenotransplantation in nonhuman primates is complicated by thrombotic microangiopathy

[1]  L. Toledo-Pereyra Xeno: The Promise of Transplanting Animal Organs Into Humans , 2001 .

[2]  D. Sachs,et al.  Peripheral blood progenitor cell mobilization and leukapheresis in pigs. , 1999, Laboratory animal science.

[3]  M. Mant,et al.  Splenectomy during partial remission in thrombotic thrombocytopenic purpura with prolonged plasma exchange dependency , 1999, American journal of hematology.

[4]  B. Lämmle,et al.  Von Willebrand Factor in Thrombotic Thrombocytopenic Purpura , 1999, Thrombosis and Haemostasis.

[5]  J. Sixma,et al.  von Willebrand factor proteolysis is deficient in classic, but not in bone marrow transplantation-associated, thrombotic thrombocytopenic purpura. , 1999, Blood.

[6]  F. Bach,et al.  Factors in Xenograft Rejection , 1999, Annals of the New York Academy of Sciences.

[7]  R. Colvin,et al.  Porcine kidney and heart transplantation in baboons undergoing a tolerance induction regimen and antibody adsorption. , 1999, Transplantation.

[8]  H. Tsai,et al.  Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura. , 1998, The New England journal of medicine.

[9]  B. Lämmle,et al.  von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome. , 1998, The New England journal of medicine.

[10]  D. Sachs,et al.  Pharmacologic immunosuppressive therapy and extracorporeal immunoadsorption in the suppression of anti‐αGal antibody in the baboon , 1998, Xenotransplantation.

[11]  J. Moake,et al.  Thrombotic thrombocytopenic purpura: understanding a disease no longer rare. , 1998, The American journal of the medical sciences.

[12]  D. Sachs,et al.  Anti-Gal(alpha)1-3Gal antibody response to porcine bone marrow in unmodified baboons and baboons conditioned for tolerance induction. , 1998, Transplantation.

[13]  D. Sachs,et al.  Depletion of anti‐Galα1–3Gal antibody in baboons by specific α‐Gal immunoaffinity columns , 1998 .

[14]  B. Lämmle,et al.  Acquired deficiency of von Willebrand factor-cleaving protease in a patient with thrombotic thrombocytopenic purpura. , 1998, Blood.

[15]  Reinhold Förster,et al.  CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells , 1998, Nature.

[16]  T. Sablinski,et al.  Removal of anti-porcine natural antibodies from human and nonhuman primate plasma in vitro and in vivo by a Galalpha1-3Galbeta1-4betaGlc-X immunoaffinity column. , 1998, Transplantation.

[17]  A. Rose,et al.  Delayed xenograft rejection of pig-to-baboon cardiac transplants after cobra venom factor therapy. , 1997, Transplantation.

[18]  P. Llamas,et al.  Management of thrombotic microangiopathy following allogeneic transplantation: what is the role of plasma exchange? , 1997, Bone Marrow Transplantation.

[19]  B. Lämmle,et al.  Deficient activity of von Willebrand factor-cleaving protease in chronic relapsing thrombotic thrombocytopenic purpura. , 1997, Blood.

[20]  R. Hawley,et al.  Xenogeneic bone marrow transplantation: II. Porcine‐specific growth factors enhance porcine bone marrow engraftment in an in vitro primate microenvironment , 1997 .

[21]  M. Denaro,et al.  Xenogeneic bone marrow transplantation: I. Cloning, expression, and species specificity of porcine IL‐3 and granulocyte‐macrophage colony‐stimulating factor , 1997 .

[22]  T. Sablinski,et al.  A study of tolerance in a concordant xenograft model. , 1997, Transplantation proceedings.

[23]  M. Horowitz,et al.  Therapeutic plasma exchange does not appear to be effective in the management of thrombotic thrombocytopenic purpura/hemolytic uremic syndrome following bone marrow transplantation. , 1995, Bone marrow transplantation.

[24]  T. Nichols,et al.  Thrombotic thrombocytopenia induced in dogs and pigs. The role of plasma and platelet vWF in animal models of thrombotic thrombocytopenic purpura. , 1995, Arteriosclerosis, thrombosis, and vascular biology.

[25]  R. Colvin,et al.  Mixed Allogeneic Chimerism And Renal Allograft Tolerance In Cynomolgus Monkeys , 1995, Transplantation.

[26]  A. Pettitt,et al.  Thrombotic microangiopathy following bone marrow transplantation. , 1994, Bone marrow transplantation.

[27]  D. Sachs,et al.  Mixed allogeneic chimeras prepared by a non-myeloablative regimen: requirement for chimerism to maintain tolerance. , 1992, Bone marrow transplantation.

[28]  J. Bertrand,et al.  Intravenous prostacyclin in thrombotic thrombocytopenic purpura: case report and review of the literature , 1991, Journal of internal medicine.

[29]  J. Kelton,et al.  Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group. , 1991, The New England journal of medicine.

[30]  T. Sundt,et al.  Specific tolerance induction across a xenogeneic barrier: production of mixed rat/mouse lymphohematopoietic chimeras using a nonlethal preparative regimen , 1990, The Journal of experimental medicine.

[31]  W. Lehmacher,et al.  Microangiopathy in patients on cyclosporine prophylaxis who developed acute graft-versus-host disease after HLA-identical bone marrow transplantation. , 1989, Blood.

[32]  R. Reddick,et al.  Thrombotic thrombocytopenia with von Willebrand factor deficiency induced by botrocetin. An animal model. , 1988, Laboratory investigation; a journal of technical methods and pathology.

[33]  R. E. Smith,et al.  Coagulation defects in cyclosporine a treated allogeneic bone marrow transplant patients , 1988, American journal of hematology.

[34]  S. Dahlén,et al.  Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. , 1987, Science.

[35]  E. Lian Pathogenesis of thrombotic thrombocytopenic purpura. , 1987, Seminars in hematology.

[36]  J. Kelton,et al.  Studies investigating platelet aggregation and release initiated by sera from patients with thrombotic thrombocytopenic purpura. , 1987, Blood.

[37]  Y. Asada,et al.  Immunohistochemistry of vascular lesion in thrombotic thrombocytopenic purpura, with special reference to factor VIII related antigen. , 1985, Thrombosis research.

[38]  D. Deykin,et al.  Unusually large plasma factor VIII:von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura. , 1982, The New England journal of medicine.

[39]  C. Hanlon,et al.  HEART TRANSPLANTATION IN PRIMATES * , 1969, Annals of the New York Academy of Sciences.

[40]  M. Brecher,et al.  Cellular source of serum lactate dehydrogenase elevation in patients with thrombotic thrombocytopenic purpura , 1998, Journal of clinical apheresis.

[41]  D. Sachs,et al.  Xenogeneic Tolerance Through Hematopoietic Cell and Thymic Transplantation , 1997 .

[42]  J. Byrnes,et al.  Thrombotic microangiopathic syndromes after bone marrow transplantation. , 1996, Cancer investigation.

[43]  D. Cooper,et al.  The Pig as Potential Organ Donor for Man , 1991 .

[44]  E. Moschcowitz Hyaline thrombosis of the terminal arterioles and capillaries : a hitherto undescribed disease , 1924 .