The effects of orchiectomy on primary and metastatic carcinoma of the breast

an increasing interest in the effects of oophorectomy on mammary carcinoma, both primary and metastatic. For more than half of that period the medical liter ature on radiation therapy has seen a sub stantial increase in the bibliography on radiation castration for metastatic breast cancer, more especially as regards the ef fects of such a procedure on the secondary deposits in bone. The encouraging regres sions of the skeletal metastases from mammary carcinoma following castration in women, still menstruating, have sug gested the possibility that orchiectomy might retard or even cause regression of mammary cancer in the male—both in the primary and metastatic lesions. The latter experiment was begunmore than two years ago at the Memorial Hospital and was noted in a preliminary report four months after the first patient was orchiectomized. Because of that result