The origins and ongoing evolution of viruses.

Genome analyses of double strand DNA tailed bacteriophages argue that they evolve by recombinational reassortment of genes and by the acquisition of novel genes as simple genetic elements termed morons. These processes suggest a model for early virus evolution, wherein viruses can be regarded less as having derived from cells and more as being partners in their mutual co-evolution.

[1]  J. Lawrence.  Gene transfer, speciation, and the evolution of bacterial genomes. , 1999, Current opinion in microbiology.

[2]  R. Hendrix,et al.  Genomic sequences of bacteriophages HK97 and HK022: pervasive genetic mosaicism in the lambdoid bacteriophages. , 2000, Journal of molecular biology.

[3]  G. Sarkis,et al.  Genome structure of mycobacteriophage D29: implications for phage evolution. , 1998, Journal of molecular biology.

[4]  D. Botstein,et al.  Molecular genetics of bacteriophage P22. , 1978, Microbiological reviews.

[5]  A. Campbell.  Phage Evolution and Speciation , 1988 .

[6]  F. Repoila,et al.  The genome of the pseudo T-even bacteriophages, a diverse group that resembles T4. , 1997, Journal of molecular biology.

[7]  B. Braden,et al.  Divergence in macromolecular assembly: X-ray crystallographic structure analysis of lumazine synthase from Brucella abortus. , 2000, Journal of molecular biology.

[8]  C. Woese.  The universal ancestor. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[9]  D. Botstein.  A THEORY OF MODULAR EVOLUTION FOR BACTERIOPHAGES * , 1980, Annals of the New York Academy of Sciences.

[10]  H. Brüssow,et al.  Comparative Genomics of Streptococcus thermophilus Phage Species Supports a Modular Evolution Theory , 1999, Journal of Virology.

[11]  D. Botstein,et al.  Evolution of the Lambdoid Phages , 1983 .

[12]  A. Campbell.  Comparative molecular biology of lambdoid phages. , 1994, Annual review of microbiology.

[13]  R. Weisberg,et al.  Packaging of coliphage lambda DNA. II. The role of the gene D protein. , 1977, Journal of molecular biology.