Extensive small bowel resection in dogs and cats: 20 cases (1998-2004).

OBJECTIVE To determine outcome in dogs and cats that underwent extensive (ie, > 50%) resection of the small intestine and identify factors associated with outcome. DESIGN Retrospective case series. ANIMALS 13 dogs and 7 cats. PROCEDURE Medical records were reviewed, and follow-up information was obtained. RESULTS In all 7 cats and in 8 of the 13 dogs, extensive intestinal resection was performed because of a foreign body. Mean+/-SD estimated percentage of intestine that was removed was 68+/-14% (range, 50% to 90%). Two dogs were euthanized 3 days after surgery because of dehiscence of the surgical site and development of septic peritonitis; 1 dog died of acute respiratory distress syndrome 5 days after surgery. The remaining 10 dogs and 7 cats were discharged from the hospital, and follow-up information was available for 15 of the 17. Median survival time was 828 days, and 12 of the 15 animals for which long-term follow-up information was available had good outcomes. However, none of the factors examined, including percentage of intestine resected, were significantly associated with outcome. CONCLUSIONS AND CLINICAL RELEVANCE Most dogs and cats that underwent extensive resection of the small intestine had a good outcome. The amount of intestine resected was not associated with outcome. These data may be useful in providing prognostic information in cases of extensive small intestinal resection.

[1]  C. Astre,et al.  Total parenteral nutrition needs in different types of short bowel syndrome , 1986, Digestive Diseases and Sciences.

[2]  G. Levine,et al.  Small-bowel resection oral intake is the stimulus for hyperplasia , 1976, The American Journal of Digestive Diseases.

[3]  Li Ning,et al.  Effect of recombinant human growth hormone and enteral nutrition on short bowel syndrome. , 2004, JPEN. Journal of parenteral and enteral nutrition.

[4]  Z. Zachariou,et al.  Poor effect of glutamin and human-EGF on autologic-allotopic transplanted ileum mucosa. , 2004, European journal of pediatric surgery.

[5]  J. Mayr,et al.  Mortality and economics in short bowel syndrome. , 2003, Best practice & research. Clinical gastroenterology.

[6]  N. Deutz,et al.  Intestinal adaptation in short bowel syndrome , 2002, ANZ journal of surgery.

[7]  J. Scolapio.  Short bowel syndrome. , 1998, JPEN. Journal of parenteral and enteral nutrition.

[8]  J. Thompson.  Inflammatory disease and outcome of short bowel syndrome. , 2000, American journal of surgery.

[9]  J. Thompson,et al.  Malnutrition impairs postresection intestinal adaptation. , 2000, JPEN - Journal of Parenteral and Enteral Nutrition.

[10]  M. Boutron‐Ruault,et al.  Long-term survival and parenteral nutrition dependence in adult patients with the short bowel syndrome. , 1999, Gastroenterology.

[11]  J. Mayr,et al.  Morbidity and Mortality of the Short-Bowel Syndrome , 1999, European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie.

[12]  K. Batts,et al.  Effect of growth hormone, glutamine, and diet on adaptation in short-bowel syndrome: a randomized, controlled study. , 1997, Gastroenterology.

[13]  D. Wilmore,et al.  Short bowel syndrome: new therapeutic approaches. , 1997, Current problems in surgery.

[14]  M. Iwafuchi,et al.  Intestinal motility after massive small bowel resection in conscious canines: comparison of acute and chronic phases. , 1996, Journal of pediatric gastroenterology and nutrition.

[15]  T. Adrian,et al.  Luminal short-chain fatty acids and postresection intestinal adaptation. , 1996, JPEN. Journal of parenteral and enteral nutrition.

[16]  J. H. Park,et al.  Growth hormone did not enhance mucosal hyperplasia after small-bowel resection. , 1996, Scandinavian journal of gastroenterology.

[17]  B. C. Chin,et al.  Hyperplasia of the Muscularis Propria in Response to Massive Intestinal Resection in Rat , 1995, Journal of pediatric gastroenterology and nutrition.

[18]  T. Ziegler,et al.  Growth hormone, glutamine, and a modified diet enhance nutrient absorption in patients with severe short bowel syndrome. , 1995, JPEN. Journal of parenteral and enteral nutrition.

[19]  K. Georgeson,et al.  Short bowel syndrome. , 1995, Seminars in pediatric surgery.

[20]  H. Boothe,et al.  Short-bowel syndrome in four dogs. , 1992, Veterinary surgery : VS.

[21]  R. Latifi,et al.  Management of the short-bowel syndrome. , 1991, The Surgical clinics of North America.

[22]  Jeejeebhoy Kn,et al.  Nutritional support and therapy in the short bowel syndrome. , 1989 .

[23]  M. Kinney.  Nutrition and Metabolism in Patient Care , 1988 .

[24]  E. Weser.  Nutritional aspects of malabsorption: short gut adaptation. , 1979, Clinics in gastroenterology.

[25]  D. Williams,et al.  Short bowel syndrome-a case report in a dog and discussion of the pathophysiology of bowel resection. , 1981, The Journal of small animal practice.

[26]  E. Weser,et al.  Intestinal adaptation to bowel resection. , 1980, Advances in internal medicine.

[27]  G. Sheldon.  Role of parenteral nutrition in patients with short bowel syndrome. , 1979, American Journal of Medicine.

[28]  J. Patterson,et al.  Short bowel syndrome following surgical correction of a double intussusception in a dog. , 1978, The Canadian veterinary journal = La revue veterinaire canadienne.

[29]  R. Williamson.  Intestinal Adaptation: Structural, Functional and Cytokinetic Changes , 1978 .

[30]  J. W. Osborne,et al.  Compensation by the residual intestine after intestinal resection in the rat. I. Influence of amount of tissue removed. , 1977, Gastroenterology.

[31]  R. Chu,et al.  Total parenteral nutrition at home: studies in patients surviving 4 months to 5 years. , 1976, Gastroenterology.

[32]  R. Dowling,et al.  Effects of oral versus intravenous nutrition on intestinal adaptation after small bowel resection in the dog. , 1976, Gastroenterology.

[33]  I. Reid.  The significance of the ileocecal valve in massive resection of the gut in puppies. , 1975, Journal of Pediatric Surgery.

[34]  D. Wilmore,et al.  The role of nutrition in the adaptation of the small intestine after massive resection. , 1971, Surgery, gynecology & obstetrics.

[35]  Burhenne Hj,et al.  Massive small bowel resection in the beagle, including laboratory data in severe undernutrition. , 1970 .

[36]  Maurice E. Shils,et al.  Modern Nutrition in Health and Disease , 1965, Diabetes.