Liver DNA alkylation after a single carcinogenic dose of dimethylnitrosamine to newborn and adult CFW Swiss mice.

[1]  J. Goodman,et al.  DNA-purine methylation in hepatic chromatin following exposure to dimethylnitrosamine or methylnitrosourea. , 1984, Biochemical pharmacology.

[2]  M. D. Topal,et al.  Mechanisms of chemical mutagenesis and carcinogenesis: effects on DNA replication of methylation at the O6-guanine position of dGTP. , 1983, Carcinogenesis.

[3]  M. Salmona,et al.  Perinatal development of styrene monooxygenase and epoxide hydrolase in rat liver microsomes and nuclei. , 1983, Chemico-biological interactions.

[4]  P. Kleihues,et al.  DNA methylation by dimethylnitrosamine in the Mongolian gerbil (Meriones unguiculatus): indications of a deficient, noninducible hepatic repair system for O6-methylguanine. , 1983, Cancer research.

[5]  J. Swenberg,et al.  Alkylation and de Novo Synthesis of Liver Cell DN Continuous Dimethylnitrosamine Exposure , 1982 .

[6]  P. Magee,et al.  alpha-Hydroxylation pathway in the in vitro metabolism of carcinogenic nitrosamines: N-nitrosodimethylamine and N-nitroso-N-methylaniline. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[7]  D. Lai,et al.  Dialkylnitrosamine bioactivation and carcinogenesis , 1980 .

[8]  S. Otani,et al.  Effect of urethan on polyamine and DNA synthesis in the regenerating rat liver. , 1980, Chemico-biological interactions.

[9]  D. Swenson,et al.  A comprehensive quantitative analysis of methylated and ethylated DNA using high pressure liquid chromatography. , 1980, Carcinogenesis.

[10]  R. Newbold,et al.  Mutagenicity of carcinogenic methylating agents is associated with a specific DNA modification , 1980, Nature.

[11]  D. Lai,et al.  Role of dimethylnitrosamine-demethylase in the metabolic activation of dimethylinitrosamine. , 1979, Chemico-biological interactions.

[12]  R. Saffhill,et al.  DNA synthesis with methylated poly(dC-dG) templates. Evidence for a competitive nature to miscoding by O(6)-methylguanine. , 1979, Biochimica et biophysica acta.

[13]  W. Lutz,et al.  Modulation of the binding of the carcinogen benzo(a)pyrene to rat liver DNA in vivo by selective induction of microsomal and nuclear aryl hydrocarbon hydroxylase activity. , 1978, Cancer research.

[14]  I. Sipes,et al.  Stimulation of microsomal dimethylnitrosamine-N-demethylase by pretreatment of mice with acetone. , 1978, Chemico-biological interactions.

[15]  J. Essigmann,et al.  Quantitative determination of transfer RNA base composition using high-pressure liquid chromatography. , 1977, Analytical biochemistry.

[16]  M. Friedman,et al.  Effects of piperonyl butoxide on dimethylnitrosamine metabolism and toxicity in Swiss mice. , 1976, Journal of toxicology and environmental health.

[17]  M. Rajewsky,et al.  Persistence of O6-ethylguanine in rat-brain DNA: correlation with nervous system-specific carcinogenesis by ethylnitrosourea. , 1974, Proceedings of the National Academy of Sciences of the United States of America.

[18]  H. Gelboin,et al.  Microsomal hydroxylases: induction and role in polycyclic hydrocarbon carcinogenesis and toxicity. , 1972, Federation proceedings.

[19]  B. Tóth.  A critical review of experiments in chemical carcinogensis using newborn animals. , 1968, Cancer research.

[20]  R. Kato,et al.  Differences among the action of phenobarbital, methylcholanthrene and male sex hormone on microsomal drug-metabolizing enzyme systems of rat liver. , 1966, Japanese journal of pharmacology.

[21]  J. Montgomery,et al.  Synthesis of Potential Anticancer Agents. XXV. Preparation of 6-Alkoxy-2-aminopurines2 , 1960 .

[22]  K. Burton.  A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. , 1956, The Biochemical journal.

[23]  T NASH,et al.  The colorimetric estimation of formaldehyde by means of the Hantzsch reaction. , 1953, The Biochemical journal.

[24]  Oliver H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.

[25]  A. Tates,et al.  Formation and stability of alkylated pyrimidines and purines (including imidazole ring-opened 7-alkylguanine) and alkylphosphotriesters in liver DNA of adult rats treated with ethylnitrosourea or dimethylnitrosamine. , 1986, Carcinogenesis.

[26]  M. Salmona,et al.  Perinatal development of cytochrome P-450, cytochrome C reductase, aryl hydrocarbon hydroxylase, styrene monooxygenase, and styrene epoxide hydrolase in rabbit liver microsomes and nuclei. , 1985, Developmental Pharmacology and Therapeutics.

[27]  P. Kleihues,et al.  O6-alkylguanine-DNA alkyltransferase activity in human brain and brain tumors. , 1984, Carcinogenesis.

[28]  V. Craddock,et al.  The activity of 3-methyladenine DNA glycosylate in animal tissues in relation to carcinogenesis. , 1982, Carcinogenesis.

[29]  G. Margison,et al.  Effects of carcinogens and partial hepatectomy upon the hepatic O6-methylguanine repair system in mice. , 1982, Carcinogenesis.

[30]  J. Swenberg,et al.  Effect of 1,2-dimethylhydrazine and diethylnitrosamine on cell replication and unscheduled DNA synthesis in target and nontarget cell populations in rat liver following chronic administration. , 1982, Cancer research.

[31]  J. Frei.  Toxicity, tissue changes, and tumor induction in inbred Swiss mice by methylnitrosamine and -amide compounds. , 1970, Cancer research.