Severe mitral valve regurgitation in polymyositis.

C linically overt or subclinical cardiac involvement is a welldescribed phenomenon in polymyositis (PM). Cardiovascular events were described as the third leading cause of death in the long run following sepsis and malignancy according to an older study. More recently, 2 studies in 364 and 162 patients with idiopathic inflammatory myopathy, respectively, showed that cardiovascular complications were the most common cause of death. However, data on valvular involvement are scarce. Here, we describe 2 cases of PM with severe mitral valve regurgitation. Our study is in compliance with the Helsinki declaration; both patients provided a written informed consent for this publication.

[1]  R. Woodman,et al.  Mortality and its predominant causes in a large cohort of patients with biopsy‐determined inflammatory myositis , 2012, Internal medicine journal.

[2]  J. Musial,et al.  Heart structure and function in patients with generalized autoimmune diseases: echocardiography with tissue Doppler study , 2011, Acta cardiologica.

[3]  Z. Odabaşı,et al.  Polymyositis presenting with cardiac manifestations: Report of two cases and review of the literature , 2010, Clinical Neurology and Neurosurgery.

[4]  I. Lundberg.  The heart in dermatomyositis and polymyositis. , 2006, Rheumatology.

[5]  G. Borgulya,et al.  Long-Term Survival of Patients With Idiopathic Inflammatory Myopathies According to Clinical Features: A Longitudinal Study of 162 Cases , 2004, Medicine.

[6]  Y. Shoenfeld,et al.  Dermatomyositis and polymyositis associated with the antiphospholipid syndrome—a novel overlap syndrome , 2000, Lupus.

[7]  E. Philbin,et al.  Heart transplant for dilated cardiomyopathy associated with polymyositis , 1999, Heart.

[8]  M. Suarez‐Almazor,et al.  Cardiac manifestations in dermato-polymyositis. , 1996, Clinical and experimental rheumatology.

[9]  Allen J. Taylor,et al.  The heart in polymyositis: A prospective evaluation of 26 patients , 1993, Clinical cardiology.

[10]  M. Behari,et al.  The heart in polymyositis-dermatomyositis , 1989, Journal of Neurology.

[11]  B. Strasberg,et al.  Polymyositic heart disease. , 1985, Chest.

[12]  G. Hutchins,et al.  The heart and cardiac conduction system in polymyositis-dermatomyositis: a clinicopathologic study of 16 autopsied patients. , 1982, The American journal of cardiology.

[13]  W. Engel,et al.  Cardiac manifestations in polymyositis. , 1978, The American journal of cardiology.

[14]  C. Pearson,et al.  A COMPUTER‐ASSISTED ANALYSIS OF 153 PATIENTS WITH POLYMYOSITIS AND DERMATOMYOSITIS , 1977, Medicine.

[15]  T. Raasakka,et al.  Cardiac involvement in polymyositis. , 1978, Scandinavian journal of rheumatology.