Simvastatin elicits dilation of isolated porcine retinal arterioles: role of nitric oxide and mevalonate-rho kinase pathways.
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Akitoshi Yoshida | L. Kuo | A. Yoshida | T. Nagaoka | T. Hein | Lih Kuo | Taiji Nagaoka | Travis W Hein
[1] A. Yeşilkaya,et al. Peroxynitrite inactivates prostacyclin synthase by heme-thiolate-catalyzed tyrosine nitration. , 1999, Drug metabolism reviews.
[2] R. Andriantsitohaina,et al. Characterization of endothelial factors involved in the vasodilatory effect of simvastatin in aorta and small mesenteric artery of the rat , 2000, British journal of pharmacology.
[3] L. Kuo,et al. Dilation of retinal arterioles in response to lactate: role of nitric oxide, guanylyl cyclase, and ATP-sensitive potassium channels. , 2006, Investigative ophthalmology & visual science.
[4] M. Iida,et al. EFFECTS OF FLUVASTATIN ON ENDOTHELIUM‐DERIVED HYPERPOLARIZING FACTOR‐ AND NITRIC OXIDE‐MEDIATED RELAXATIONS IN ARTERIES OF HYPERTENSIVE RATS , 2004, Clinical and experimental pharmacology & physiology.
[5] M. Selley. Simvastatin prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced striatal dopamine depletion and protein tyrosine nitration in mice , 2005, Brain Research.
[6] 佐藤 俊之. The mechanism of thrombin-induced prostacyclin synthesis in human endothelial cells with reference to the gene transcription of prostacyclin-related enzymes and Ca[2+] kinetics , 2000 .
[7] R. Brandes,et al. Lovastatin maintains nitric oxide--but not EDHF-mediated endothelium-dependent relaxation in the hypercholesterolemic rabbit carotid artery. , 1999, Atherosclerosis.
[8] 今野 優. Retinal blood flow changes in type I diabetes : A long-term follow-up study , 1996 .
[9] M. Brown,et al. cDNA cloning of MEV, a mutant protein that facilitates cellular uptake of mevalonate, and identification of the point mutation responsible for its gain of function. , 1992, The Journal of biological chemistry.
[10] L. Yannuzzi,et al. The effects of lipid lowering on diabetic retinopathy. , 1991, American journal of ophthalmology.
[11] S. Gupte,et al. Hypoxia enhances a cGMP-independent nitric oxide relaxing mechanism in pulmonary arteries. , 2003, American journal of physiology. Lung cellular and molecular physiology.
[12] C. Sobey,et al. Opposing Roles of Endothelial and Smooth Muscle Phosphatidylinositol 3-Kinase in Vasoconstriction: Effects of Rho-Kinase and Hypertension , 2005, Journal of Pharmacology and Experimental Therapeutics.
[13] C. Owsley,et al. Statins and other cholesterol-lowering medications and the presence of glaucoma. , 2004, Archives of ophthalmology.
[14] T. Sawamura,et al. Statin inhibits leukocyte-endothelial interaction and prevents neuronal death induced by ischemia-reperfusion injury in the rat retina. , 2002, Archives of ophthalmology.
[15] C. McCulloch,et al. Statin and aspirin therapy are associated with decreased rates of choroidal neovascularization among patients with age-related macular degeneration. , 2004, American journal of ophthalmology.
[16] S. Chłopicki,et al. Statins as coronary vasodilators in isolated bovine coronary arteries--involvement of PGI2 and NO. , 2005, Prostaglandins, leukotrienes, and essential fatty acids.
[17] M. Herrera,et al. Cardiovascular effects of lovastatin in normotensive and spontaneously hypertensive rats. , 1998, General pharmacology.
[18] T. Lüscher,et al. Heterogeneity of endothelium-dependent regulation in ophthalmic and ciliary arteries. , 1993, Investigative ophthalmology & visual science.
[19] D. Lefer,et al. The effects of statins on endothelium, inflammation and cardioprotection. , 2005, Drug news & perspectives.
[20] K. Kaibuchi,et al. Rho GTPase/Rho Kinase Negatively Regulates Endothelial Nitric Oxide Synthase Phosphorylation through the Inhibition of Protein Kinase B/Akt in Human Endothelial Cells , 2002, Molecular and Cellular Biology.
[21] T. Nurkiewicz,et al. Calcium‐Independent Release of Endothelial Nitric Oxide in the Arteriolar Network: Onset During Rapid Juvenile Growth , 2004, Microcirculation.
[22] L. Kuo,et al. Effect of systemic administration of simvastatin on retinal circulation. , 2006, Archives of ophthalmology.
[23] A. Pastuszyn,et al. Cytochrome p-450 epoxygenase products contribute to attenuated vasoconstriction after chronic hypoxia. , 2003, American journal of physiology. Heart and circulatory physiology.
[24] K. Franchini,et al. Simvastatin Prevents Load-Induced Protein Tyrosine Nitration in Overloaded Hearts , 2004, Hypertension.
[25] N. Delanty,et al. Vascular effects of statins in stroke. , 1997, Stroke.
[26] B. Tesfamariam. The Effects of HMG-CoA Reductase Inhibitors on Endothelial Function , 2006, American journal of cardiovascular drugs : drugs, devices, and other interventions.
[27] M. Manzoni,et al. Biosynthesis and biotechnological production of statins by filamentous fungi and application of these cholesterol-lowering drugs , 2002, Applied Microbiology and Biotechnology.
[28] M. Herrera,et al. Effect of simvastatin on vascular smooth muscle responsiveness: involvement of Ca(2+) homeostasis. , 2001, European journal of pharmacology.
[29] R. Cohen,et al. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle , 1994, Nature.
[30] R. Caldwell,et al. Pravastatin sodium activates endothelial nitric oxide synthase independent of its cholesterol-lowering actions. , 1999, Journal of the American College of Cardiology.
[31] J. Liao,et al. oxLDL specifically impairs endothelium-dependent, NO-mediated dilation of coronary arterioles. , 2000, American journal of physiology. Heart and circulatory physiology.
[32] A. Mueck,et al. Fluvastatin increases prostacyclin and decreases endothelin production by human umbilical vein endothelial cells. , 2000, International journal of clinical pharmacology and therapeutics.
[33] S. Watts,et al. Inhibition of nitric oxide-induced vasodilation by gap junction inhibitors: a potential role for a cGMP-independent nitric oxide pathway. , 1996, Journal of vascular research.
[34] M. Glucksberg,et al. Direct measurement of retinal microvascular pressures in the live, anesthetized cat. , 1993, Microvascular research.
[35] L. Kuo,et al. Requisite roles of A2A receptors, nitric oxide, and KATP channels in retinal arteriolar dilation in response to adenosine. , 2005, Investigative ophthalmology & visual science.
[36] C. Curcio,et al. Complex mutations of USH2A gene denote ARRP , 2003, The British journal of ophthalmology.
[37] J. Goldstein,et al. Regulation of the mevalonate pathway , 1990, Nature.
[38] J. Bertoglio,et al. Modulation of COX-2 Expression by Statins in Human Aortic Smooth Muscle Cells , 2001, The Journal of Biological Chemistry.
[39] F. Fyhrquist,et al. Atorvastatin completely inhibits VEGF-induced ACE upregulation in human endothelial cells. , 2004, American journal of physiology. Heart and circulatory physiology.
[40] R. Busse,et al. Endothelium-derived epoxyeicosatrienoic acids and vascular function. , 2006, Hypertension.
[41] B. Vollrath,et al. Effects of statins on vascular function of endothelin‐1 , 2005, British journal of pharmacology.
[42] L. Schmetterer,et al. Assessment of optic disk blood flow in patients with open-angle glaucoma. , 2000, American journal of ophthalmology.
[43] M. Wolzt,et al. Effect of pravastatin on responsiveness to N-monomethyl-L-arginine in patients with hypercholesterolaemia. , 2002, Atherosclerosis.
[44] U. Laufs,et al. Direct vascular effects of HMG-CoA reductase inhibitors. , 2000, Trends in cardiovascular medicine.
[45] R. Andriantsitohaina,et al. Simvastatin and Ca(2+) signaling in endothelial cells: involvement of rho protein. , 2001, Biochemical and biophysical research communications.
[46] R. Gregg,et al. Differential effects of pravastatin, simvastatin, and atorvastatin on Ca2+ release and vascular reactivity. , 1999, Journal of cardiovascular pharmacology.
[47] J. Falck,et al. Contribution of 20-HETE to the vasodilator actions of nitric oxide in renal arteries. , 1998, American journal of physiology. Renal physiology.
[48] R. Gryglewski,et al. Comparison of Endothelial Pleiotropic Actions of Angiotensin Converting Enzyme Inhibitors and Statins , 2001, Annals of the New York Academy of Sciences.
[49] G. Barnes,et al. A novel method to assess reactivities of retinal microcirculation. , 1994, Microvascular research.
[50] U. Laufs,et al. Post-transcriptional Regulation of Endothelial Nitric Oxide Synthase mRNA Stability by Rho GTPase* , 1998, The Journal of Biological Chemistry.
[51] P. Neuvonen,et al. Grapefruit juice—simvastatin interaction: Effect on serum concentrations of simvastatin, simvastatin acid, and HMG‐CoA reductase inhibitors , 1998, Clinical pharmacology and therapeutics.
[52] P. Neuvonen,et al. Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations , 1998, Clinical pharmacology and therapeutics.
[53] L. Kuo,et al. cAMP-independent dilation of coronary arterioles to adenosine : role of nitric oxide, G proteins, and K(ATP) channels. , 1999, Circulation research.
[54] L. Dobrucki,et al. Increased Nitric Oxide Bioavailability in Endothelial Cells Contributes to the Pleiotropic Effect of Cerivastatin , 2002, Circulation.
[55] G. Fried,et al. Effects of nitric oxide donors and inhibitors of nitric oxide signalling on endothelin- and serotonin-induced contractions in human placental arteries. , 2002, Acta physiologica Scandinavica.
[56] U. Laufs,et al. Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. , 1998, Circulation.
[57] B. Kemp,et al. Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors. , 2004, American journal of physiology. Heart and circulatory physiology.
[58] M. Moskowitz,et al. Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[59] N. Youhnovski,et al. Specific Nitration at Tyrosine 430 Revealed by High Resolution Mass Spectrometry as Basis for Redox Regulation of Bovine Prostacyclin Synthase* , 2003, The Journal of Biological Chemistry.
[60] J. Vane,et al. Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin. , 1978, Pharmacological reviews.
[61] R. Roman,et al. Mechanism of cGMP contribution to the vasodilator response to NO in rat middle cerebral arteries. , 2002, American journal of physiology. Heart and circulatory physiology.
[62] G. Ying,et al. Reduced foveolar choroidal blood flow in eyes with increasing AMD severity. , 2005, Investigative ophthalmology & visual science.
[63] L. Kuo,et al. LDLs impair vasomotor function of the coronary microcirculation: role of superoxide anions. , 1998, Circulation research.
[64] L. Dobrucki,et al. Statin-stimulated nitric oxide release from endothelium. , 2001, Medical science monitor : international medical journal of experimental and clinical research.
[65] M. Lagarde,et al. Human lymphocytes stimulate prostacyclin synthesis in human umbilical vein endothelial cells. Involvement of endothelial cPLA2 , 2000, Journal of leukocyte biology.
[66] K. Nakagawa,et al. The mechanism of thrombin-induced prostacyclin synthesis in human endothelial cells with reference to the gene transcription of prostacyclin-related enzymes and Ca2+ kinetics. , 1999, Journal of pharmacological and toxicological methods.
[67] A. Tsujikawa,et al. Simvastatin inhibits leukocyte accumulation and vascular permeability in the retinas of rats with streptozotocin-induced diabetes. , 2004, The American journal of pathology.
[68] J. Liao,et al. Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. , 2001, Arteriosclerosis, thrombosis, and vascular biology.
[69] H. Syddall,et al. Risk of macular degeneration in users of statins: cross sectional study , 2001, BMJ : British Medical Journal.