Chemical proteomics approaches for identifying the cellular targets of natural products
暂无分享,去创建一个
[1] V. DeRose,et al. Picazoplatin, an azide-containing platinum(II) derivative for target analysis by click chemistry. , 2013, Journal of the American Chemical Society.
[2] M. K. Harper,et al. A Central Strategy for Converting Natural Products into Fluorescent Probes , 2006, Chembiochem : a European journal of chemical biology.
[3] J. L. La Clair,et al. Spirohexenolide A targets human macrophage migration inhibitory factor (hMIF). , 2013, Journal of natural products.
[4] S. Sieber,et al. The two faces of potent antitumor duocarmycin-based drugs: a structural dissection reveals disparate motifs for DNA versus aldehyde dehydrogenase 1 affinity. , 2013, Angewandte Chemie.
[5] Han-Ming Shen,et al. A Quantitative Chemical Proteomics Approach to Profile the Specific Cellular Targets of Andrographolide, a Promising Anticancer Agent That Suppresses Tumor Metastasis* , 2014, Molecular & Cellular Proteomics.
[6] T. Zor,et al. Species selective diazirine positioning in tag-free photoactive quorum sensing probes. , 2013, Chemical communications.
[7] L. Tietze,et al. Glycosidic prodrugs of highly potent bifunctional duocarmycin derivatives for selective treatment of cancer. , 2010, Angewandte Chemie.
[8] S. Sieber,et al. Duocarmycin analogues target aldehyde dehydrogenase 1 in lung cancer cells. , 2012, Angewandte Chemie.
[9] P. Nordlund,et al. Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay , 2013, Science.
[10] J. Taunton,et al. Photo-leucine incorporation reveals the target of a cyclodepsipeptide inhibitor of cotranslational translocation. , 2007, Journal of the American Chemical Society.
[11] J. Hemingway,et al. Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7 , 2016, Proceedings of the National Academy of Sciences.
[12] S. Sieber,et al. Making a Long Journey Short: Alkyne Functionalization of Natural Product Scaffolds. , 2016, Chemistry.
[13] S. Sieber,et al. Antibiotic activity and target discovery of three-membered natural product-derived heterocycles in pathogenic bacteria , 2012 .
[14] Helge Weissig,et al. Functional interrogation of the kinome using nucleotide acyl phosphates. , 2007, Biochemistry.
[15] P. Gmeiner,et al. Covalent molecular probes for class A G protein-coupled receptors: advances and applications. , 2015, ACS chemical biology.
[16] S. Sieber,et al. Alkynol natural products target ALDH2 in cancer cells by irreversible binding to the active site. , 2015, Chemical communications.
[17] B. Cravatt,et al. Simultaneous structure–activity studies and arming of natural products by C–H amination reveal cellular targets of eupalmerin acetate , 2013, Nature Chemistry.
[18] C. D. de Koster,et al. Selective enrichment of azide-containing peptides from complex mixtures. , 2009, Journal of proteome research.
[19] James J. La Clair,et al. Natural product mode of action (MOA) studies: a link between natural and synthetic worlds , 2010 .
[20] S. Sieber,et al. Beta-lactones as privileged structures for the active-site labeling of versatile bacterial enzyme classes. , 2008, Angewandte Chemie.
[21] Emmanuelle Thinon,et al. Multifunctional protein labeling via enzymatic N-terminal tagging and elaboration by click chemistry , 2011, Nature Protocols.
[22] A. Cazenave-Gassiot,et al. Targeting Lipid Esterases in Mycobacteria Grown Under Different Physiological Conditions Using Activity-based Profiling with Tetrahydrolipstatin (THL)* , 2013, Molecular & Cellular Proteomics.
[23] Bernhard Kuster,et al. Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors , 2007, Nature Biotechnology.
[24] Bin Liu,et al. Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum , 2015, Nature Communications.
[25] A. Olson,et al. Mechanistic and structural requirements for active site labeling of phosphoglycerate mutase by spiroepoxides. , 2007, Molecular bioSystems.
[26] M. Bogyo,et al. Activity-based probes as a tool for functional proteomic analysis of proteases , 2008, Expert review of proteomics.
[27] S. Sieber,et al. Copper‐Assisted Click Reactions for Activity‐Based Proteomics: Fine‐Tuned Ligands and Refined Conditions Extend the Scope of Application , 2013, Chembiochem : a European journal of chemical biology.
[28] J. L. La Clair,et al. Seriniquinone, a selective anticancer agent, induces cell death by autophagocytosis, targeting the cancer-protective protein dermcidin , 2014, Proceedings of the National Academy of Sciences.
[29] M. Meijler,et al. Diazirine based photoaffinity labeling. , 2012, Bioorganic & medicinal chemistry.
[30] Mingzi M. Zhang,et al. Robust fluorescent detection of protein fatty-acylation with chemical reporters. , 2009, Journal of the American Chemical Society.
[31] Matthias Mann,et al. Use of stable isotope labeling by amino acids in cell culture as a spike-in standard in quantitative proteomics , 2011, Nature Protocols.
[32] B. Cravatt,et al. Proteome-wide Mapping of Cholesterol-Interacting Proteins in Mammalian Cells , 2013, Nature Methods.
[33] Ian Collins,et al. Photoaffinity labeling in target- and binding-site identification. , 2015, Future medicinal chemistry.
[34] Jennifer A. Prescher,et al. Finding the right (bioorthogonal) chemistry. , 2014, ACS chemical biology.
[35] Luke G Green,et al. A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes. , 2002, Angewandte Chemie.
[36] B. Cravatt,et al. Remodeling Natural Products: Chemistry and Serine Hydrolase Activity of a Rocaglate-Derived β-Lactone , 2014, Journal of the American Chemical Society.
[37] G. Charron,et al. Comparative analysis of cleavable azobenzene-based affinity tags for bioorthogonal chemical proteomics. , 2010, Chemistry & biology.
[38] Christian Ochsenfeld,et al. Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues. , 2015, Angewandte Chemie.
[39] W. Marsden. I and J , 2012 .
[40] Benjamin F. Cravatt,et al. A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles , 2013, Nature Methods.
[41] S. Sze,et al. Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. , 2013, Angewandte Chemie.
[42] S. Sieber,et al. The biological targets of acivicin inspired 3-chloro- and 3-bromodihydroisoxazole scaffolds. , 2010, Chemical communications.
[43] R. Finn,et al. Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions , 2013, Proceedings of the National Academy of Sciences.
[44] Amber L. Couzens,et al. The CRAPome: a Contaminant Repository for Affinity Purification Mass Spectrometry Data , 2013, Nature Methods.
[45] Thomas Böttcher,et al. Natural products and their biological targets: proteomic and metabolomic labeling strategies. , 2010, Angewandte Chemie.
[46] M. Mann,et al. Exponentially Modified Protein Abundance Index (emPAI) for Estimation of Absolute Protein Amount in Proteomics by the Number of Sequenced Peptides per Protein*S , 2005, Molecular & Cellular Proteomics.
[47] R. Rosenfeld. Nature , 2009, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
[48] L. Marnett,et al. Identification of protein targets of 4-hydroxynonenal using click chemistry for ex vivo biotinylation of azido and alkynyl derivatives. , 2008, Chemical research in toxicology.
[49] G. Drewes,et al. Tracking cancer drugs in living cells by thermal profiling of the proteome , 2014, Science.
[50] K. Altmann,et al. Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin. , 2010, Biochemical pharmacology.
[51] Yinliang Yang,et al. Target profiling of 4-hydroxyderricin in S. aureus reveals seryl-tRNA synthetase binding and inhibition by covalent modification. , 2013, Molecular bioSystems.
[52] S. Sieber,et al. Fimbrolide Natural Products Disrupt Bioluminescence of Vibrio By Targeting Autoinducer Biosynthesis and Luciferase Activity. , 2016, Angewandte Chemie.
[53] Steven R. Tannenbaum,et al. In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line , 2016, Scientific Reports.
[54] Jennifer A. Prescher,et al. A comparative study of bioorthogonal reactions with azides. , 2006, ACS chemical biology.
[55] Karunakaran A Kalesh,et al. Target profiling of zerumbone using a novel cell-permeable clickable probe and quantitative chemical proteomics. , 2015, Chemical communications.
[56] S. Sieber,et al. Target discovery of acivicin in cancer cells elucidates its mechanism of growth inhibition , 2014, Chemical science.
[57] Steven J Brown,et al. Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes , 2009, Nature Biotechnology.
[58] Anna K. Schrey,et al. Comprehensive identification of staurosporine-binding kinases in the hepatocyte cell line HepG2 using Capture Compound Mass Spectrometry (CCMS). , 2010, Journal of proteome research.
[59] Leo Eberl,et al. Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound. , 2002, Microbiology.
[60] S. Yao,et al. In situ imaging and proteome profiling indicate andrographolide is a highly promiscuous compound , 2015, Scientific Reports.
[61] Kai Liu,et al. Activity‐Based Protein Profiling: Recent Advances in Probe Development and Applications , 2015, Chembiochem : a European journal of chemical biology.
[62] Raymond E Moellering,et al. How chemoproteomics can enable drug discovery and development. , 2012, Chemistry & biology.
[63] A. Scholten,et al. On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases , 2013, Journal of the American Chemical Society.
[64] E. Weerapana,et al. Covalent protein modification: the current landscape of residue-specific electrophiles. , 2015, Current opinion in chemical biology.
[65] B. Cravatt,et al. Disparate proteome reactivity profiles of carbon electrophiles. , 2008, Nature chemical biology.
[66] M. Katan,et al. Global Profiling of Huntingtin-associated protein E (HYPE)-Mediated AMPylation through a Chemical Proteomic Approach* , 2015, Molecular & Cellular Proteomics.
[67] Knut Reinert,et al. Tools for Label-free Peptide Quantification , 2012, Molecular & Cellular Proteomics.
[68] Xu Wu,et al. Clickable analogue of cerulenin as chemical probe to explore protein palmitoylation. , 2015, ACS chemical biology.
[69] G. G. Stokes. "J." , 1890, The New Yale Book of Quotations.
[70] S. Sieber,et al. Omuralide and vibralactone: differences in the proteasome- β-lactone-γ-lactam binding scaffold alter target preferences. , 2014, Angewandte Chemie.
[71] B. Cravatt,et al. Chemical proteomic probes for profiling cytochrome p450 activities and drug interactions in vivo. , 2007, Chemistry & biology.
[72] M. Dallman,et al. Multifunctional Reagents for Quantitative Proteome-Wide Analysis of Protein Modification in Human Cells and Dynamic Profiling of Protein Lipidation During Vertebrate Development** , 2015, Angewandte Chemie.
[73] B. Cravatt,et al. A tandem orthogonal proteolysis strategy for high-content chemical proteomics. , 2005, Journal of the American Chemical Society.
[74] John A. Robinson,et al. Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa , 2010, Science.
[75] K. Resing,et al. Comparison of Label-free Methods for Quantifying Human Proteins by Shotgun Proteomics*S , 2005, Molecular & Cellular Proteomics.
[76] Reinout Raijmakers,et al. Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics , 2009, Nature Protocols.
[77] N. Gregersen,et al. A cleavable azide resin for direct click chemistry mediated enrichment of alkyne-labeled proteins. , 2014, Chemical communications.
[78] S. Zahler,et al. Pretubulysin derived probes as novel tools for monitoring the microtubule network via activity-based protein profiling and fluorescence microscopy. , 2012, Molecular bioSystems.
[79] K. Aizawa,et al. Toll-like Receptors as a Target of Food-derived Anti-inflammatory Compounds* , 2014, The Journal of Biological Chemistry.
[80] S. Sieber,et al. Rugulactone and its Analogues Exert Antibacterial Effects through Multiple Mechanisms Including Inhibition of Thiamine Biosynthesis , 2012, Chembiochem : a European journal of chemical biology.
[81] D. Piomelli,et al. Activity-Based Probe for N-Acylethanolamine Acid Amidase. , 2015, ACS chemical biology.
[82] Y. Kondo,et al. Eupalmerin acetate, a novel anticancer agent from Caribbean gorgonian octocorals, induces apoptosis in malignant glioma cells via the c-Jun NH2-terminal kinase pathway , 2007, Molecular Cancer Therapeutics.
[83] S. Sieber,et al. Beta-lactam probes as selective chemical-proteomic tools for the identification and functional characterization of resistance associated enzymes in MRSA. , 2009, Journal of the American Chemical Society.
[84] V. DeRose,et al. Multifunctional Pt(II) Reagents: Covalent Modifications of Pt Complexes Enable Diverse Structural Variation and In-Cell Detection. , 2016, Accounts of chemical research.
[85] S. Sieber,et al. Electrophilic natural products and their biological targets. , 2012, Natural product reports.
[86] R Riccio,et al. In cell scalaradial interactome profiling using a bio-orthogonal clickable probe. , 2014, Chemical communications.
[87] Herbert Waldmann,et al. Target identification for small bioactive molecules: finding the needle in the haystack. , 2013, Angewandte Chemie.
[88] A. Hermetter,et al. Activity-Based Probes for Studying the Activity of Flavin-Dependent Oxidases and for the Protein Target Profiling of Monoamine Oxidase Inhibitors , 2012, Angewandte Chemie.
[89] G. Preston,et al. Photo-induced covalent cross-linking for the analysis of biomolecular interactions. , 2013, Chemical Society reviews.
[90] E. Weerapana,et al. A Caged Electrophilic Probe for Global Analysis of Cysteine Reactivity in Living Cells. , 2015, Journal of the American Chemical Society.
[91] A. Adibekian,et al. Proteome-Wide Profiling of Targets of Cysteine reactive Small Molecules by Using Ethynyl Benziodoxolone Reagents. , 2015, Angewandte Chemie.
[92] F. Young. Biochemistry , 1955, The Indian Medical Gazette.
[93] Benjamin F. Cravatt,et al. A roadmap to evaluate the proteome-wide selectivity of covalent kinase inhibitors , 2014, Nature chemical biology.
[94] B. Cravatt,et al. Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP)—a general method for mapping sites of probe modification in proteomes , 2007, Nature Protocols.
[95] S. Sieber,et al. Unraveling the protein targets of vancomycin in living S. aureus and E. faecalis cells. , 2011, Journal of the American Chemical Society.
[96] D. Boger,et al. CC-1065 and the duocarmycins: unraveling the keys to a new class of naturally derived DNA alkylating agents. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[97] Matthew R. Pratt,et al. An alkyne-aspirin chemical reporter for the detection of aspirin-dependent protein modification in living cells. , 2013, Journal of the American Chemical Society.
[98] M. Bogyo,et al. The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains. , 2012, Chemistry & biology.
[99] Youli Xiao,et al. Profiling of Multiple Targets of Artemisinin Activated by Hemin in Cancer Cell Proteome. , 2016, ACS chemical biology.
[100] B. Kuster,et al. A Simple and Effective Cleavable Linker for Chemical Proteomics Applications* , 2012, Molecular & Cellular Proteomics.
[101] S. Sieber,et al. Showdomycin as a versatile chemical tool for the detection of pathogenesis-associated enzymes in bacteria. , 2010, Journal of the American Chemical Society.
[102] Jigang Wang,et al. Mapping sites of aspirin-induced acetylations in live cells by quantitative acid-cleavable activity-based protein profiling (QA-ABPP) , 2015, Scientific Reports.
[103] S. Sieber,et al. Vibralactone as a tool to study the activity and structure of the ClpP1P2 complex from Listeria monocytogenes. , 2011, Angewandte Chemie.
[104] A. Burlingame,et al. Hypothemicin, a fungal natural product, identifies therapeutic targets in Trypanosoma brucei , 2013, eLife.
[105] D. Liebler,et al. Quantitative Chemoproteomics for Site-Specific Analysis of Protein Alkylation by 4-Hydroxy-2-Nonenal in Cells , 2015, Analytical chemistry.
[106] S. Sieber,et al. Beta-lactams as selective chemical probes for the in vivo labeling of bacterial enzymes involved in cell wall biosynthesis, antibiotic resistance, and virulence. , 2008, Journal of the American Chemical Society.
[107] B. Cravatt,et al. Activity-based protein profiling: from enzyme chemistry to proteomic chemistry. , 2008, Annual review of biochemistry.
[108] C. Thiele,et al. Photo-leucine and photo-methionine allow identification of protein-protein interactions in living cells , 2005, Nature Methods.
[109] M. Wenk,et al. Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities. , 2010, Journal of the American Chemical Society.
[110] X. Zou,et al. Disulfide- and terminal alkyne-functionalized magnetic silica particles for enrichment of azido glycopeptides. , 2012, Chemical communications.
[111] Jongmin Park,et al. Investigation of Specific Binding Proteins to Photoaffinity Linkers for Efficient Deconvolution of Target Protein. , 2016, ACS chemical biology.
[112] David Baker,et al. Quantitative reactivity profiling predicts functional cysteines in proteomes , 2010, Nature.
[113] M. Rask-Andersen,et al. Trends in the exploitation of novel drug targets , 2011, Nature Reviews Drug Discovery.
[114] Bernhard Kuster,et al. Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present , 2012, Analytical and Bioanalytical Chemistry.
[115] S. Eykyn. Microbiology , 1950, The Lancet.
[116] Matthias Mann,et al. Quantitative shotgun proteomics: considerations for a high-quality workflow in immunology , 2014, Nature Immunology.
[117] D. Mierke,et al. Methionine acts as a “magnet” in photoaffinity crosslinking experiments , 2006, FEBS letters.
[118] K. Rumbaugh,et al. Perception and degradation of N-acyl homoserine lactone quorum sensing signals by mammalian and plant cells. , 2011, Chemical reviews.
[119] Anna E Speers,et al. Profiling enzyme activities in vivo using click chemistry methods. , 2004, Chemistry & biology.
[120] Jack Taunton,et al. Target Identification by Diazirine Photo‐Cross‐Linking and Click Chemistry , 2009, Current protocols in chemical biology.
[121] Edward W. Tate,et al. Chemoproteomic Evaluation of the Polyacetylene Callyspongynic Acid. , 2015, Chemistry.
[122] J. Kozarich,et al. ATP Acyl Phosphate Reactivity Reveals Native Conformations of Hsp90 Paralogs and Inhibitor Target Engagement. , 2015, Biochemistry.
[123] Neil Genzlinger. A. and Q , 2006 .
[124] A. Saghatelian,et al. Target discovery in small-molecule cell-based screens by in situ proteome reactivity profiling , 2005, Nature Biotechnology.
[125] M. Zeltner,et al. Click and release: fluoride cleavable linker for mild bioorthogonal separation. , 2016, Chemical communications.
[126] L. Christophorou. Science , 2018, Emerging Dynamics: Science, Energy, Society and Values.
[127] Morten Meldal,et al. Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides. , 2002, The Journal of organic chemistry.
[128] Erin E. Carlson,et al. Selective penicillin-binding protein imaging probes reveal substructure in bacterial cell division. , 2012, ACS chemical biology.
[129] Shao Q Yao,et al. Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe. , 2011, Chemical communications.
[130] B. Cravatt,et al. A suite of activity-based probes for human cytochrome P450 enzymes. , 2009, Journal of the American Chemical Society.
[131] 宁北芳,et al. 疟原虫var基因转换速率变化导致抗原变异[英]/Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A , 2005 .