Registration of 3D CT and ultrasound datasets of the spine using bone structures.

OBJECTIVE In navigated orthopedic surgery, accurate registration of bones is of major interest. Usually, this registration is performed using landmarks positioned directly on the bone surface. These landmarks must be exposed during surgery. Our goal is to avoid the exposure of bone surface for the sole purpose of registration by using an intraoperative ultrasound device that can localize the bone through tissue. METHOD We propose an algorithm for the registration of CT and ultrasound datasets that takes into account the fact that ultrasound produces very noisy images (speckle) and shows only parts of the bone surface. This part is made from the CT dataset. Next, a surface volume registration is performed by searching for a position of the estimated surface that maximizes the average gray value of the voxels in the ultrasound dataset covered by the surface. RESULTS The algorithm was implemented and validated using an ex vivo preparation of a human lumbar spine with surrounding muscle tissue. On the basis of this data, the method has a large radius of convergence and a repeatability of 0.5 mm for displacement and 0.5 degrees for rotation. CONCLUSIONS A robust algorithm for the registration of 3D CT and ultrasound datasets is presented. The computation time seems sufficiently short to permit intraoperative use.

[1]  T. Peters,et al.  An algorithmic overview of surface registration techniques for medical imaging , 2000, Medical Image Anal..

[2]  Jay B. West,et al.  Predicting error in rigid-body point-based registration , 1998, IEEE Transactions on Medical Imaging.

[3]  Yoshikazu Nakajima,et al.  Effects of CT threshold value to make a surface bone model on accuracy of shape-based registration in a CT-based navigation system for hip surgery , 2001, CARS.

[4]  Ma Bin-rong,et al.  A review of medical image registration , 1999 .

[5]  Max A. Viergever,et al.  A survey of medical image registration , 1998, Medical Image Anal..

[6]  R W Prager,et al.  Rapid calibration for 3-D freehand ultrasound. , 1998, Ultrasound in medicine & biology.

[7]  F. Lizzi Ultrasound Imaging , 1991, Proceedings Technology Requirements for Biomedical Imaging.

[8]  David J. Hawkes,et al.  AcouStick: A Tracked A-Mode Ultrasonography System for Registration in Image-Guided Surgery , 1999, MICCAI.

[9]  Roy W. Martin,et al.  Three-dimensional ultrasound imaging using multiple magnetic tracking systems and miniature magnetic sensors , 1995, 1995 IEEE Ultrasonics Symposium. Proceedings. An International Symposium.

[10]  W. Eric L. Grimson,et al.  An Integrated Visualization System for Surgical Planning and Guidance Using Image Fusion and Interventional Imaging , 1999, MICCAI.

[11]  Jérôme Tonetti,et al.  Percutaneous Computer Assisted Iliosacral Screwing: Clinical Validation , 2000, MICCAI.

[12]  D M Muratore,et al.  Beam calibration without a phantom for creating a 3-D freehand ultrasound system. , 2001, Ultrasound in medicine & biology.

[13]  Benoit M. Dawant,et al.  Vertebral surface extraction from ultrasound images for technology-guided therapy , 1999, Medical Imaging.