A theoretic framework for intelligent expert systems in medical encounter evaluation

: This paper describes a novel approach to implementation of a medical diagnosis expert system that can assist physicians with their daily practices. Differential artificial intelligence techniques are incorporated into a multi-stage expert system to best represent the various phases of the patient diagnosis process. A weighted scoring system is used to represent the subjective analysis stage, while a rule-based fuzzy expert system is employed to both interpret laboratory tests and imaging findings and suggest the final diagnosis. A model of various patient flow scenarios is presented to demonstrate the functionality of the proposed expert system. An actual example of patient walkthrough is used to demonstrate various computation steps from recording the patient chief complaint to arriving at the final diagnosis. It is shown that the conclusion arrived at by using the proposed system is consistent with a common diagnosis of a third party specialist who is asked to evaluate the performance of the system.

[1]  K. Shulman,et al.  Fuzzy logic pharmacokinetic modeling: Application to lithium concentration prediction , 1997, Clinical pharmacology and therapeutics.

[2]  Elie Sanchez,et al.  FUZZY INFERENCE AND MEDICAL DIAGNOSIS, A CASE STUDY , 1990 .

[3]  Shyi-Ming Chen,et al.  A weighted fuzzy reasoning algorithm for medical diagnosis , 1994, Decis. Support Syst..

[4]  Ramón López de Mántaras,et al.  RENOIR: An expert system using fuzzy logic for rheumatology diagnosis , 1994, Int. J. Intell. Syst..

[5]  M. Madheswaran,et al.  A Hybrid Fuzzy-Neural System for Computer-Aided Diagnosis of Ultrasound Kidney Images Using Prominent Features , 2008, Journal of Medical Systems.

[6]  Ashish Mangalampalli,et al.  A neural network based clinical decision-support system for efficient diagnosis and fuzzy-based prescription of gynecological diseases using homoeopathic medicinal system , 2006, Expert Syst. Appl..

[7]  Peter Szolovits,et al.  Artificial intelligence in medical diagnosis. , 1988, Annals of internal medicine.

[8]  Elif Derya Übeyli Comparison of different classification algorithms in clinical decision‐making , 2007, Expert Syst. J. Knowl. Eng..

[9]  Luis M. Laita,et al.  A logic and computer algebra-based expert system for diagnosis of anorexia , 2002, Math. Comput. Simul..

[10]  Elif Derya Übeyli Detection of electrocardiogram beats using a fuzzy similarity index , 2007, Expert Syst. J. Knowl. Eng..

[11]  Christopher J. R. Green,et al.  Verification and validation of expert systems , 1991 .

[12]  Tzung-Pei Hong,et al.  Design of a Self-Adaptive Brain Tumor Diagnostic System , 1995, J. Inf. Sci. Eng..

[13]  Mu-Yen Chen,et al.  Integrating data mining with case-based reasoning for chronic diseases prognosis and diagnosis , 2007, Expert Syst. Appl..