Towards direct reconstruction from a gamma camera based on Compton scattering

The Compton scattering camera (sometimes called the electronically collimated camera) has been shown by others to have the potential to better the photon counting statistics and the energy resolution of the Anger camera for imaging in SPECT. By using coincident detection of Compton scattering events on two detecting planes, a photon can be localized to having been sourced on the surface of a cone. New algorithms are needed to achieve fully three-dimensional reconstruction of the source distribution from such a camera. If a complete set of cone-surface projections are collected over an infinitely extending plane, it is shown that the reconstruction problem is not only analytically solvable, but also overspecified in the absence of measurement uncertainties. Two approaches to direct reconstruction are proposed, both based on the photons which travel perpendicularly between the detector planes. Results of computer simulations are presented which demonstrate the ability of the algorithms to achieve useful reconstructions in the absence of measurement uncertainties (other than those caused by quantization). The modifications likely to be required in the presence of realistic measurement uncertainties are discussed.

[1]  Gabor T. Herman,et al.  Image reconstruction from projections : the fundamentals of computerized tomography , 1980 .

[2]  J. M. Nightingale,et al.  Gamma-radiation imaging system based on the Compton effect , 1977 .

[3]  M. Singh,et al.  An electronically collimated gamma camera for single photon emission computed tomography. Part I: Theoretical considerations and design criteria. , 1983, Medical physics.

[4]  Bruce W. Suter,et al.  Foundations of Hankel transform algorithms , 1991 .

[5]  M. Singh,et al.  Experimental test-object study of electronically collimated SPECT. , 1990, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[6]  Robert J. Ott,et al.  Gamma ray imaging with silicon detectors — A Compton camera for radionuclide imaging in medicine , 1988 .

[7]  Thomas A. Verdon,et al.  Anger Scintillation Camera as Whole-Body Counter for Quantitation and Visualization of Radionuclide—Reply , 1977 .

[8]  R. Diehl The comptel experiment on the NASA Gamma-Ray Observatory , 1989 .

[9]  Philip J. Bones,et al.  Algorithms to numerically evaluate the Hankel transform , 1993 .

[10]  Manbir Singh,et al.  An electronically collimated gamma camera for single photon emission computed tomography. Part II: Image reconstruction and preliminary experimental measurements , 1983 .

[11]  Bruce D. Smith Cone-beam tomography: recent advances and a tutorial review , 1990 .

[12]  D. P. Saylor,et al.  Design of an efficient position sensitive gamma ray detector for nuclear medicine. , 1986, Physics in medicine and biology.

[13]  D. Doria,et al.  An electronically collimated gamma camera for single photon emission computed tomography. Part II: Image reconstruction and preliminary experimental measurements. , 1983, Medical physics.

[14]  D. Wehe,et al.  A source reconstruction method for multiple scatter Compton cameras , 1991, Conference Record of the 1991 IEEE Nuclear Science Symposium and Medical Imaging Conference.

[15]  R Leahy,et al.  Three-dimensional maximum-likelihood reconstruction for an electronically collimated single-photon-emission imaging system. , 1990, Journal of the Optical Society of America. A, Optics and image science.

[16]  T. Kamae,et al.  Prototype design of multiple Compton gamma-ray camera , 1988 .

[17]  Robert Stanton,et al.  Radiological Imaging: The Theory of Image Formation, Detection, and Processing , 1983 .

[18]  S. A. Audet,et al.  A 3 × 3 silicon drift chamber array for application in an electronic collimator , 1988 .