Review on the Medicinal uses and Pharmacological aspects of Plectranthus tenuiflorus from the Labiatae Family of Saudi Arabia

Plectranthus tenuiflorus belong to the Lamiaceae family also known as P. aegypticus. It is widely used in various disorders; eardrop for ear ache, sore throat, inflammation of middle ear, respiratory system infections, and abdominal disorders. The main objectives of this review are to summarizes the phytochemical, medicinal uses and pharmacological activities of Plectranthus tenuiflorus. The current works related to Plectranthus tenuiflorus were reviewed from numerous books, Journals and internet source (Science Direct, PubMed, Google Search engine, and abstracts). Phytochemical studies on fresh leaves of Plectranthus tenuiflorus showed the presence of thymol, the essential oil (62.53%), which is the major constituent, triterpenoids, coumarins and hydrolysable tannins, while flavonoids, alkaloids, steroids, anthraquinones, condensed tannins, cardiac-and anthraquinone glycosides are absent. The Paper chromatography separation technique reported that the leaf contains 7 protein amino acids represented by Ala; His; Phe; Asn; Asp; Glu and Leu. Pharmacological activities such as, Antiplasmodial, Antitrypanosomal, Antileishmanial, Cytotoxicity, Antioxidant, Antischistosomal, Antimicrobial, Antiphytoviral and Wound healing activity have been reported. Further scientific investigations on Plectranthus tenuiflorus are needed to explore toxicity and clinical efficacy and as well as to explore the therapeutic effects of major secondary metabolites of Plectranthus tenuiflorus.

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