Functional Links Between Aβ Toxicity, Endocytic Trafficking, and Alzheimer’s Disease Risk Factors in Yeast
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Eric M Reiman | Anders Olofsson | Susan Lindquist | David A Bennett | Rudolph E Tanzi | Chee Yeun Chung | D. Bennett | E. Reiman | S. Lindquist | J. Shulman | R. Tanzi | Denis A. Evans | Julie S. Valastyan | K. Caldwell | G. Caldwell | J. L. Goodman | S. Hamamichi | K. Matlack | Sebastian Treusch | B. Bevis | C. Chung | A. Olofsson | Denis A Evans | A. Parrado | Joshua M Shulman | Jessica L Goodman | Valeriya Baru | Haesun Han | M. Lindhagen-Persson | Philip L. Dejager | Malin Lindhagen-Persson | Kim A. Caldwell | Sebastian Treusch | Shusei Hamamichi | Kent E S Matlack | Valeriya Baru | Antonio Parrado | Brooke J Bevis | Julie S Valastyan | Haesun Han | Philip L DeJager | Kim A Caldwell | Guy A Caldwell | S. Treusch | P. Dejager
[1] Christoph Lange,et al. Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. , 2008, American journal of human genetics.
[2] B. Penke,et al. Amyloid β‐peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease , 2004 .
[3] K D Wittrup,et al. Secretion efficiency in Saccharomyces cerevisiae of bovine pancreatic trypsin inhibitor mutants lacking disulfide bonds is correlated with thermodynamic stability. , 1998, Biochemistry.
[4] P. Toselli,et al. Structure and function analysis of the CMS/CIN85 protein family identifies actin-bundling properties and heterotypic-complex formation , 2007, Journal of Cell Science.
[5] M. Arévalo-Rodríguez,et al. An improved system for estradiol-dependent regulation of gene expression in yeast , 2007, Microbial cell factories.
[6] Jürgen Götz,et al. Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models , 2010, Cell.
[7] Michael S. Wolfe,et al. Presenilin: Running with Scissors in the Membrane , 2007, Cell.
[8] F. LaFerla. Pathways linking Abeta and tau pathologies. , 2010, Biochemical Society transactions.
[9] D. G. Clark,et al. Common variants in MS4A4/MS4A6E, CD2uAP, CD33, and EPHA1 are associated with late-onset Alzheimer’s disease , 2011, Nature Genetics.
[10] L. Kiemeney,et al. Corrigendum: Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer , 2009, Nature Genetics.
[11] Nick C Fox,et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease, and shows evidence for additional susceptibility genes , 2009, Nature Genetics.
[12] A. Adler,et al. The Rsp5 Ubiquitin Ligase Binds to and Ubiquitinates Members of the Yeast CIN85-Endophilin Complex, Sla1-Rvs167* , 2004, Journal of Biological Chemistry.
[13] S. Lindquist,et al. Screening for Amyloid Aggregation by Semi-Denaturing Detergent-Agarose Gel Electrophoresis , 2008, Journal of visualized experiments : JoVE.
[14] Jason J. Corneveaux,et al. CR1 is associated with amyloid plaque burden and age‐related cognitive decline , 2011, Annals of neurology.
[15] M. Kaksonen,et al. PtdIns(4,5)P2 turnover is required for multiple stages during clathrin- and actin-dependent endocytic internalization , 2007, The Journal of cell biology.
[16] J. Hardy,et al. The Amyloid Hypothesis of Alzheimer ’ s Disease : Progress and Problems on the Road to Therapeutics , 2009 .
[17] Jonathan S. Weissman,et al. Construction, Verification and Experimental Use of Two Epitope-Tagged Collections of Budding Yeast Strains , 2005, Comparative and functional genomics.
[18] David A. Bennett,et al. Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles , 2009, Neurology.
[19] Kristina D. Micheva,et al. Identification and Characterization of a Nerve Terminal-enriched Amphiphysin Isoform* , 1997, The Journal of Biological Chemistry.
[20] J. Rogers,et al. hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes , 2007, Genomics.
[21] J. Bessereau,et al. [C. elegans: of neurons and genes]. , 2003, Medecine sciences : M/S.
[22] Songsong Cao,et al. Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model , 2008, Proceedings of the National Academy of Sciences.
[23] S. Lindquist,et al. A suite of Gateway® cloning vectors for high‐throughput genetic analysis in Saccharomyces cerevisiae , 2007, Yeast.
[24] Michael R Dores,et al. Interaction between Epsin/Yap180 adaptors and the scaffolds Ede1/Pan1 is required for endocytosis. , 2008, Molecular biology of the cell.
[25] V. Haucke,et al. Clathrin‐Mediated Endocytosis at Synapses , 2007, Traffic.
[26] S. Lindquist,et al. Hsp104 Catalyzes Formation and Elimination of Self-Replicating Sup35 Prion Conformers , 2004, Science.
[27] H. Pelham. Control of protein exit from the endoplasmic reticulum. , 1989, Annual review of cell biology.
[28] Joshua A. Kritzer,et al. Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models , 2010, Disease Models & Mechanisms.
[29] Carl W. Cotman,et al. Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis , 2003, Science.
[30] Shaomin Li,et al. Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory , 2008, Nature Medicine.
[31] J. Hay,et al. α-Synuclein Delays Endoplasmic Reticulum (ER)-to-Golgi Transport in Mammalian Cells by Antagonizing ER/Golgi SNAREs , 2010, Molecular biology of the cell.
[32] P. Bosco,et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease , 2009, Nature Genetics.
[33] Zhaohui S. Qin,et al. A second generation human haplotype map of over 3.1 million SNPs , 2007, Nature.
[34] S. Brenner. The genetics of Caenorhabditis elegans. , 1974, Genetics.
[35] D. Bennett,et al. Intermediate Phenotypes Identify Divergent Pathways to Alzheimer's Disease , 2010, PloS one.
[36] D. Bozyczko‐Coyne,et al. CEP‐1347/KT‐7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Aβ‐induced cortical neuron apoptosis , 2001, Journal of neurochemistry.
[37] L. Martin,et al. Long-term culture of mouse cortical neurons as a model for neuronal development, aging, and death. , 2002, Journal of neurobiology.
[38] S. Yan,et al. Role of mitochondrial amyloid-beta in Alzheimer's disease. , 2010, Journal of Alzheimer's disease : JAD.
[39] Roger M. Nitsch,et al. Intracellular Aβ and cognitive deficits precede β-amyloid deposition in transgenic arcAβ mice , 2007, Neurobiology of Aging.
[40] R. Nitsch,et al. Intracellular Abeta and cognitive deficits precede beta-amyloid deposition in transgenic arcAbeta mice. , 2007, Neurobiology of aging.
[41] M. Vestling,et al. Amyloid-β Oligomer Specificity Mediated by the IgM Isotype – Implications for a Specific Protective Mechanism Exerted by Endogenous Auto-Antibodies , 2010, PloS one.
[42] S. Lindquist,et al. α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models , 2006, Science.
[43] C. Link,et al. Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[44] J. Trojanowski,et al. Targeting Amyloid-β Peptide (Aβ) Oligomers by Passive Immunization with a Conformation-selective Monoclonal Antibody Improves Learning and Memory in Aβ Precursor Protein (APP) Transgenic Mice* , 2006, Journal of Biological Chemistry.
[45] M. Vidal,et al. C. elegans ORFeome version 3.1: increasing the coverage of ORFeome resources with improved gene predictions. , 2004, Genome research.
[46] S. Lindquist,et al. α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity , 2009, Nature Genetics.
[47] D. Selkoe,et al. The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain. , 2000, Biochemistry.
[48] S. Lindquist,et al. Modelling neurodegeneration in Saccharomyces cerevisiae: why cook with baker's yeast? , 2010, Nature Reviews Neuroscience.
[49] B. Barneda-Zahonero,et al. Soluble Oligomers of Amyloid-β Peptide Disrupt Membrane Trafficking of α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptor Contributing to Early Synapse Dysfunction* , 2011, The Journal of Biological Chemistry.
[50] Nick C Fox,et al. Letter abstract - Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's Disease , 2009 .
[51] E. Koo,et al. Amyloid Precursor Protein Trafficking, Processing, and Function* , 2008, Journal of Biological Chemistry.
[52] J. Fleming,et al. Basic culture methods. , 1995, Methods in cell biology.
[53] J. Haines,et al. ApoE-4 and Age at Onset of Alzheimer's Disease , 1997, Neurology.
[54] Nick C Fox,et al. Common variants in ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer’s disease , 2011, Nature Genetics.
[55] Sudha Seshadri,et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. , 2010, JAMA.
[56] Steve D. M. Brown,et al. α-Synuclein impairs macroautophagy: implications for Parkinson’s disease , 2010, The Journal of cell biology.
[57] L. Mucke,et al. Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model , 2007, Science.
[58] G. Gibson,et al. A mitocentric view of Alzheimer's disease suggests multi-faceted treatments. , 2010, Journal of Alzheimer's disease : JAD.
[59] C. Jack,et al. Alzheimer's Disease Neuroimaging Initiative , 2008 .
[60] S. Lindquist,et al. Yeast Cells Provide Insight into Alpha-Synuclein Biology and Pathobiology , 2003, Science.
[61] A. Linstedt. Faculty Opinions recommendation of Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. , 2006 .