The objective of this study is to asses clients knowledge, attitude, practice and associated factors towards tuberculosis in Yejube health center Northwest Ethiopia. Institution based cross-sectional study was conducted at Yejube health center among 392 individuals from March to June 2017. Data were analyzed mannually. Descriptive statistics was used to determine level of practice and its predictors. Out of the total 83.2% of respondents said that they heard about TB. Around 70.4% had awareness that TB can be transmitted through air droplet and knew cough (36.4%) was the most commonly stated symptom of TB while modern drugs used in health institution (80.7%) was the preferred choice of treatment. Similarly, 81.8% said that they would seek treatment at health facility if they had symptoms related to TB and 32.1% experience fear if themselves had TB. Individuals with educational level unable to read and write had poor level of practice on TB prevention compared to college and above. Individuals having poor attitude towards TB are also greater than those of having poor practice to having good attitude and individuals having poor knowledge towards TB has higher than having poor practice to having good knowledge. Most patients had little information about the cause of TB, transmission, prevention and associated factors. Level of practice is affected by poor attitude, poor knowledge. Therefore, it needs a strategy directed to bring a significant change in their attitude and knowledge towards patient with TB.
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