Towards the design of 3D multiscale instructive tissue engineering constructs: Current approaches and trends.

[1]  Tal Dvir,et al.  Nanotechnological strategies for engineering complex tissues. , 2020, Nature nanotechnology.

[2]  G. Hortelano,et al.  Fibronectin-Alginate microcapsules improve cell viability and protein secretion of encapsulated Factor IX-engineered human mesenchymal stromal cells , 2015, Artificial cells, nanomedicine, and biotechnology.

[3]  J. Kanczler,et al.  Bone Tissue Engineering , 2015, Current Molecular Biology Reports.

[4]  Sara M. Oliveira,et al.  Layer-by-layer assembled cell instructive nanocoatings containing platelet lysate. , 2015, Biomaterials.

[5]  J. Mano,et al.  Myoconductive and osteoinductive free-standing polysaccharide membranes. , 2015, Acta biomaterialia.

[6]  R. Reis,et al.  Cell selective chitosan microparticles as injectable cell carriers for tissue regeneration. , 2015, Biomaterials.

[7]  João F Mano,et al.  Assembly of cell-laden hydrogel fiber into non-liquefied and liquefied 3D spiral constructs by perfusion-based layer-by-layer technique , 2015, Biofabrication.

[8]  J. Mano Designing biomaterials for tissue engineering based on the deconstruction of the native cellular environment , 2015 .

[9]  J. Mano,et al.  Fast and Mild Strategy, Using Superhydrophobic Surfaces, to Produce Collagen/Platelet Lysate Gel Beads for Skin Regeneration , 2015, Stem Cell Reviews and Reports.

[10]  Rui L Reis,et al.  Assembling Human Platelet Lysate into Multiscale 3D Scaffolds for Bone Tissue Engineering. , 2015, ACS biomaterials science & engineering.

[11]  A. McGuigan,et al.  A microgroove patterned multiwell cell culture plate for high‐throughput studies of cell alignment , 2014, Biotechnology and bioengineering.

[12]  João F Mano,et al.  High-throughput screening for integrative biomaterials design: exploring advances and new trends. , 2014, Trends in biotechnology.

[13]  Ali Khademhosseini,et al.  Fiber-assisted molding (FAM) of surfaces with tunable curvature to guide cell alignment and complex tissue architecture. , 2014, Small.

[14]  P. Supaphol,et al.  Development of polycaprolactone porous scaffolds by combining solvent casting, particulate leaching, and polymer leaching techniques for bone tissue engineering: Development Of Polycaprolactone Porous Scaffolds , 2014 .

[15]  Shan-hui Hsu,et al.  The substrate-dependent regeneration capacity of mesenchymal stem cell spheroids derived on various biomaterial surfaces. , 2014, Biomaterials science.

[16]  R. Reis,et al.  Layer‐by‐Layer Assembly of Light‐Responsive Polymeric Multilayer Systems , 2014 .

[17]  J. Mano,et al.  Molecular interactions driving the layer-by-layer assembly of multilayers. , 2014, Chemical reviews.

[18]  Myron Spector,et al.  Adaptive growth factor delivery from a polyelectrolyte coating promotes synergistic bone tissue repair and reconstruction , 2014, Proceedings of the National Academy of Sciences.

[19]  R. Reis,et al.  Photopatterned antibodies for selective cell attachment. , 2014, Langmuir : the ACS journal of surfaces and colloids.

[20]  C. Bai,et al.  Induction of immunomodulatory monocytes by human mesenchymal stem cell‐derived hepatocyte growth factor through ERK1/2 , 2014, Journal of leukocyte biology.

[21]  David A. Williams,et al.  Modulating the stem cell niche for tissue regeneration , 2014, Nature Biotechnology.

[22]  G. Vunjak‐Novakovic,et al.  Human adipose‐derived cells can serve as a single‐cell source for the in vitro cultivation of vascularized bone grafts , 2014, Journal of tissue engineering and regenerative medicine.

[23]  R. D'Souza,et al.  Biomaterial-mesenchymal stem cell constructs for immunomodulation in composite tissue engineering. , 2014, Tissue engineering. Part A.

[24]  N. Rosenthal,et al.  Preparing the ground for tissue regeneration: from mechanism to therapy , 2014, Nature Medicine.

[25]  A. Wagers,et al.  Stem cell aging: mechanisms, regulators and therapeutic opportunities , 2014, Nature Medicine.

[26]  P. Bonaldo,et al.  Extracellular matrix: A dynamic microenvironment for stem cell niche , 2014, Biochimica et biophysica acta.

[27]  Josep A Planell,et al.  Biofabrication of tissue constructs by 3D bioprinting of cell-laden microcarriers , 2014, Biofabrication.

[28]  M. Gou,et al.  Magnetically controllable 3D microtissues based on magnetic microcryogels. , 2014, Lab on a chip.

[29]  Richard A Que,et al.  Modification of Biomaterials with a Self‐Protein Inhibits the Macrophage Response , 2014, Advanced healthcare materials.

[30]  B. Boyan,et al.  A review on the wettability of dental implant surfaces II: Biological and clinical aspects. , 2014, Acta biomaterialia.

[31]  H. Ceylan,et al.  Bone-like mineral nucleating peptide nanofibers induce differentiation of human mesenchymal stem cells into mature osteoblasts. , 2014, Biomacromolecules.

[32]  Rui L Reis,et al.  Engineering Biomolecular Microenvironments for Cell Instructive Biomaterials , 2014, Advanced healthcare materials.

[33]  João F Mano,et al.  Nanostructured polymeric coatings based on chitosan and dopamine-modified hyaluronic acid for biomedical applications. , 2014, Small.

[34]  Tian Jian Lu,et al.  Engineering physical microenvironment for stem cell based regenerative medicine. , 2014, Drug discovery today.

[35]  Changchun Zhou,et al.  Biomimetic fabrication of a three-level hierarchical calcium phosphate/collagen/hydroxyapatite scaffold for bone tissue engineering , 2014, Biofabrication.

[36]  J. Mano,et al.  Magnetic composite biomaterials for tissue engineering. , 2014, Biomaterials science.

[37]  C. Chrelias,et al.  The immunomodulatory and anti-apoptotic effect of dexamethasone in imminent preterm labor: an experimental study. , 2014, European journal of pharmacology.

[38]  J. Lewis,et al.  3D Bioprinting of Vascularized, Heterogeneous Cell‐Laden Tissue Constructs , 2014, Advanced materials.

[39]  J. Santerre,et al.  Biomaterials in co-culture systems: towards optimizing tissue integration and cell signaling within scaffolds. , 2014, Biomaterials.

[40]  João F. Mano,et al.  Polyelectrolyte multilayered assemblies in biomedical technologies. , 2014, Chemical Society reviews.

[41]  Dong-Yol Yang,et al.  Hierarchical multilayer assembly of an ordered nanofibrous scaffold via thermal fusion bonding , 2014, Biofabrication.

[42]  Kristi S. Anseth,et al.  Mechanical memory and dosing influence stem cell fate , 2014, Nature materials.

[43]  C. Chua,et al.  Cartilage Tissue Engineering with Silk Fibroin Scaffolds Fabricated by Indirect Additive Manufacturing Technology , 2014, Materials.

[44]  C. Custódio,et al.  Functionalized Microparticles Producing Scaffolds in Combination with Cells , 2014 .

[45]  David J Mooney,et al.  Injectable, porous, and cell-responsive gelatin cryogels. , 2014, Biomaterials.

[46]  A. I. Neto,et al.  In vivo high-content evaluation of three-dimensional scaffolds biocompatibility. , 2014, Tissue engineering. Part C, Methods.

[47]  S. Hashimoto,et al.  Adhesion of gels by silica particle. , 2014, The journal of physical chemistry. B.

[48]  A. Lucas,et al.  Novel Model for the Description of the Controlled Release of 5-Fluorouracil from PLGA and PLA Foamed Scaffolds Impregnated in Supercritical CO2 , 2014 .

[49]  S. Hashimoto,et al.  Surface Modification Method for Adhesion of Gels , 2014 .

[50]  S. Nigam,et al.  Growth factor–heparan sulfate “switches” regulating stages of branching morphogenesis , 2014, Pediatric Nephrology.

[51]  R L Reis,et al.  Bottom-up approach to construct microfabricated multi-layer scaffolds for bone tissue engineering , 2014, Biomedical microdevices.

[52]  D. Burgess,et al.  Microspheres Prepared with PLGA Blends for Delivery of Dexamethasone for Implantable Medical Devices , 2014, Pharmaceutical Research.

[53]  R. Bellamkonda,et al.  A Perspective on Immunomodulation and Tissue Repair , 2014, Annals of Biomedical Engineering.

[54]  B. Hsiao,et al.  Biodegradable poly(lactic acid)/hydroxyl apatite 3D porous scaffolds using high-pressure molding and salt leaching , 2014, Journal of Materials Science.

[55]  GeunHyung Kim,et al.  Cell-printed hierarchical scaffolds consisting of micro-sized polycaprolactone (PCL) and electrospun PCL nanofibers/cell-laden alginate struts for tissue regeneration. , 2014, Journal of materials chemistry. B.

[56]  Thomas Eschenhagen,et al.  Cardiac tissue engineering: state of the art. , 2014, Circulation research.

[57]  Hao Tang,et al.  Progress Report on the Generation of Polyfunctional Microscale Particles for Programmed Self-Assembly , 2014, Chemistry of materials : a publication of the American Chemical Society.

[58]  Sara M. Oliveira,et al.  Cell interactions with superhydrophilic and superhydrophobic surfaces , 2014 .

[59]  David A. Brafman,et al.  Constructing stem cell microenvironments using bioengineering approaches. , 2013, Physiological genomics.

[60]  N. Maffulli,et al.  Platelet-rich plasma for managing pain and inflammation in osteoarthritis , 2013, Nature Reviews Rheumatology.

[61]  R. Mahato,et al.  Emerging Trends in Cell and Gene Therapy , 2013, Humana Press.

[62]  Seong-Kyoon Choi,et al.  Improved neural progenitor cell proliferation and differentiation on poly(lactide-co-glycolide) scaffolds coated with elastin-like polypeptide. , 2013, Journal of biomedical materials research. Part B, Applied biomaterials.

[63]  R L Reis,et al.  Effect of crosslinking in chitosan/aloe vera-based membranes for biomedical applications. , 2013, Carbohydrate polymers.

[64]  M. Gawaz,et al.  Platelets in tissue repair: control of apoptosis and interactions with regenerative cells. , 2013, Blood.

[65]  P. Supaphol,et al.  Development of polycaprolactone porous scaffolds by combining solvent casting, particulate leaching, and polymer leaching techniques for bone tissue engineering. , 2013, Journal of biomedical materials research. Part A.

[66]  Yangbin Xu,et al.  The effects of gradients of nerve growth factor immobilized PCLA scaffolds on neurite outgrowth in vitro and peripheral nerve regeneration in rats. , 2013, Biomaterials.

[67]  Hyoungshin Park,et al.  3D Structural Patterns in Scalable, Elastomeric Scaffolds Guide Engineered Tissue Architecture , 2013, Advanced materials.

[68]  Sara M. Oliveira,et al.  Nanocoatings containing sulfated polysaccharides prepared by layer-by-layer assembly as models to study cell-material interactions. , 2013, Journal of materials chemistry. B.

[69]  A. Khademhosseini,et al.  DNA directed self-assembly of shape-controlled hydrogels , 2013, Nature Communications.

[70]  H. Kamiya,et al.  Acceleration of autologous in vivo recellularization of decellularized aortic conduits by fibronectin surface coating. , 2013, Biomaterials.

[71]  Shayn M Peirce,et al.  Multiscale computational models of complex biological systems. , 2013, Annual review of biomedical engineering.

[72]  S. Hsu,et al.  Substrate-dependent Wnt signaling in MSC differentiation within biomaterial-derived 3D spheroids. , 2013, Biomaterials.

[73]  João F Mano,et al.  Magnetic force-based tissue engineering and regenerative medicine. , 2013, Journal of biomedical nanotechnology.

[74]  R. Reis,et al.  Interactions between exogenous FGF-2 and sulfonic groups: in situ characterization and impact on the morphology of human adipose-derived stem cells. , 2013, Langmuir : the ACS journal of surfaces and colloids.

[75]  J. Jansen,et al.  Osteochondral tissue regeneration using a bilayered composite hydrogel with modulating dual growth factor release kinetics in a rabbit model. , 2013, Journal of controlled release : official journal of the Controlled Release Society.

[76]  Rui R. Costa,et al.  Multifunctional compartmentalized capsules with a hierarchical organization from the nano to the macro scales. , 2013, Biomacromolecules.

[77]  Feng Xu,et al.  Directed self-assembly of microscale hydrogels by electrostatic interaction , 2013, Biofabrication.

[78]  A. Mandegary,et al.  Effect of EGF and FGF on the expansion properties of human umbilical cord mesenchymal cells , 2013, In Vitro Cellular & Developmental Biology - Animal.

[79]  Shaoyi Jiang,et al.  Zwitterionic hydrogels implanted in mice resist the foreign-body reaction , 2013, Nature Biotechnology.

[80]  Jim Hu,et al.  Cell density during differentiation can alter the phenotype of bone marrow-derived macrophages , 2013, Cell & Bioscience.

[81]  Fabio Ganazzoli,et al.  Surface topography effects in protein adsorption on nanostructured carbon allotropes. , 2013, Langmuir : the ACS journal of surfaces and colloids.

[82]  J. Mano,et al.  Combinatorial on-chip study of miniaturized 3D porous scaffolds using a patterned superhydrophobic platform. , 2013, Small.

[83]  N. Johnson,et al.  Controlled delivery of heparin-binding EGF-like growth factor yields fast and comprehensive wound healing. , 2013, Journal of controlled release : official journal of the Controlled Release Society.

[84]  Rui L Reis,et al.  Hierarchical Fibrillar Scaffolds Obtained by Non‐conventional Layer‐By‐Layer Electrostatic Self‐Assembly , 2013, Advanced healthcare materials.

[85]  B. Sacchetti,et al.  Bone Ingrowth and Vascular Supply in Experimental Spinal Fusion With Platelet-Rich Plasma , 2013, Spine.

[86]  J. Mano,et al.  Interactions between cells or proteins and surfaces exhibiting extreme wettabilities , 2013 .

[87]  Rui L. Reis,et al.  Nanostructured 3D Constructs Based on Chitosan and Chondroitin Sulphate Multilayers for Cartilage Tissue Engineering , 2013, PloS one.

[88]  R. Reis,et al.  Controlled release strategies for bone, cartilage, and osteochondral engineering--Part I: recapitulation of native tissue healing and variables for the design of delivery systems. , 2013, Tissue engineering. Part B, Reviews.

[89]  Rui L Reis,et al.  Multilayered hierarchical capsules providing cell adhesion sites. , 2013, Biomacromolecules.

[90]  N. Nakatsuji Mesoscopic science, where materials become life and life inspires materials. A great opportunity to push back the frontiers of life, materials, and biomaterials sciences. , 2013, Biomaterials science.

[91]  R. Reis,et al.  Chitosan–chondroitin sulphate nanoparticles for controlled delivery of platelet lysates in bone regenerative medicine , 2012, Journal of tissue engineering and regenerative medicine.

[92]  J. Ramshaw,et al.  Collagen-based layer-by-layer coating on electrospun polymer scaffolds. , 2012, Biomaterials.

[93]  R. Reis,et al.  The role of organic solvent on the preparation of chitosan scaffolds by supercritical assisted phase inversion , 2012 .

[94]  J. Jansen,et al.  Chitosan/bioactive glass nanoparticle composite membranes for periodontal regeneration. , 2012, Acta biomaterialia.

[95]  J. Mano,et al.  Secondary structure of rhBMP-2 in a protective biopolymeric carrier material. , 2012, Biomacromolecules.

[96]  P. Krebsbach,et al.  Growth factor delivery: how surface interactions modulate release in vitro and in vivo. , 2012, Advanced drug delivery reviews.

[97]  Georg N Duda,et al.  Biomaterial delivery of morphogens to mimic the natural healing cascade in bone. , 2012, Advanced drug delivery reviews.

[98]  R. Reis,et al.  Enhancement of osteogenic differentiation of human adipose derived stem cells by the controlled release of platelet lysates from hybrid scaffolds produced by supercritical fluid foaming. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[99]  P. Bártolo,et al.  Additive manufacturing of tissues and organs , 2012 .

[100]  R. Reis,et al.  From nano- to macro-scale: nanotechnology approaches for spatially controlled delivery of bioactive factors for bone and cartilage engineering. , 2012, Nanomedicine.

[101]  Srinivas Madduri,et al.  Growth factor delivery systems and repair strategies for damaged peripheral nerves. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[102]  Boyang Zhang,et al.  Mosaic Hydrogels: One‐Step Formation of Multiscale Soft Materials , 2012, Advanced materials.

[103]  R. Reis,et al.  Sulfonic groups induce formation of filopodia in mesenchymal stem cells , 2012 .

[104]  Michiya Matsusaki,et al.  Development of Three-Dimensional Tissue Models Based on Hierarchical Cell Manipulation Using Nanofilms , 2012 .

[105]  GeunHyung Kim,et al.  Preparation and Characterization of 3D Composite Scaffolds Based on Rapid-Prototyped PCL/β-TCP Struts and Electrospun PCL Coated with Collagen and HA for Bone Regeneration , 2012 .

[106]  Lutz Claes,et al.  Fracture healing under healthy and inflammatory conditions , 2012, Nature Reviews Rheumatology.

[107]  J. Mano,et al.  Production methodologies of polymeric and hydrogel particles for drug delivery applications , 2012, Expert opinion on drug delivery.

[108]  Feng Xu,et al.  The assembly of cell-encapsulating microscale hydrogels using acoustic waves. , 2011, Biomaterials.

[109]  Feng Xu,et al.  Three‐Dimensional Magnetic Assembly of Microscale Hydrogels , 2011, Advanced materials.

[110]  T P Vail,et al.  Structured three-dimensional co-culture of mesenchymal stem cells with chondrocytes promotes chondrogenic differentiation without hypertrophy. , 2011, Osteoarthritis and cartilage.

[111]  F. Sailhan,et al.  The performance of BMP-2 loaded TCP/HAP porous ceramics with a polyelectrolyte multilayer film coating. , 2011, Biomaterials.

[112]  J. Simon,et al.  Immune responses to implants - a review of the implications for the design of immunomodulatory biomaterials. , 2011, Biomaterials.

[113]  P. Gao,et al.  Recent advances in materials for extended-release antibiotic delivery system , 2011, The Journal of Antibiotics.

[114]  Scott J Hollister,et al.  Scaffold translation: barriers between concept and clinic. , 2011, Tissue engineering. Part B, Reviews.

[115]  Sara M. Oliveira,et al.  Chemical modification of bioinspired superhydrophobic polystyrene surfaces to control cell attachment/proliferation , 2011 .

[116]  A. Mobasheri,et al.  Three‐dimensional high‐density co‐culture with primary tenocytes induces tenogenic differentiation in mesenchymal stem cells , 2011, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[117]  G. Hannink,et al.  Injectable bone-graft substitutes: current products, their characteristics and indications, and new developments. , 2011, Injury.

[118]  Yukun Zhang,et al.  In vitro osteogenesis of human adipose-derived stem cells by coculture with human umbilical vein endothelial cells. , 2011, Biochemical and biophysical research communications.

[119]  R. Reis,et al.  Nanostructured natural-based polyelectrolyte multilayers to agglomerate chitosan particles into scaffolds for tissue engineering. , 2011, Tissue engineering. Part A.

[120]  Sara M. Oliveira,et al.  Development of an injectable system based on elastin-like recombinamer particles for tissue engineering applications , 2011 .

[121]  J. Mano,et al.  Polymer‐based microparticles in tissue engineering and regenerative medicine , 2011, Biotechnology progress.

[122]  Yaojiong Wu,et al.  Epigenetic Dysregulation in Mesenchymal Stem Cell Aging and Spontaneous Differentiation , 2011, PLoS ONE.

[123]  J Malda,et al.  Bioprinting of hybrid tissue constructs with tailorable mechanical properties , 2011, Biofabrication.

[124]  J. Turnbull,et al.  Extracellular matrix and cell signalling: the dynamic cooperation of integrin, proteoglycan and growth factor receptor. , 2011, The Journal of endocrinology.

[125]  Katja Schenke-Layland,et al.  Skin tissue engineering--in vivo and in vitro applications. , 2011, Advanced drug delivery reviews.

[126]  C. V. van Blitterswijk,et al.  Chitosan scaffolds containing hyaluronic acid for cartilage tissue engineering. , 2011, Tissue engineering. Part C, Methods.

[127]  A. I. Neto,et al.  High-throughput evaluation of interactions between biomaterials, proteins and cells using patterned superhydrophobic substrates , 2011 .

[128]  J. Freedman,et al.  Platelets and the immune continuum , 2011, Nature Reviews Immunology.

[129]  F. Tay,et al.  Differences between top-down and bottom-up approaches in mineralizing thick, partially demineralized collagen scaffolds. , 2011, Acta biomaterialia.

[130]  Sunghoon Kwon,et al.  Three-dimensional fluidic self-assembly by axis translation of two-dimensionally fabricated microcomponents in railed microfluidics. , 2011, Small.

[131]  Changyou Gao,et al.  A hybrid scaffold of poly(lactide-co-glycolide) sponge filled with fibrin gel for cartilage tissue engineering , 2011 .

[132]  Rui L Reis,et al.  Three-dimensional plotted scaffolds with controlled pore size gradients: Effect of scaffold geometry on mechanical performance and cell seeding efficiency. , 2011, Acta biomaterialia.

[133]  J. Couchman,et al.  Syndecans as cell surface receptors: Unique structure equates with functional diversity. , 2011, Matrix biology : journal of the International Society for Matrix Biology.

[134]  Paula T Hammond,et al.  Tissue integration of growth factor-eluting layer-by-layer polyelectrolyte multilayer coated implants. , 2011, Biomaterials.

[135]  A. Caplan,et al.  Mesenchymal stem cells: mechanisms of inflammation. , 2011, Annual review of pathology.

[136]  Sheng Lin-Gibson,et al.  Combinatorial and High‐Throughput Screening of Biomaterials , 2011, Advanced materials.

[137]  J. Mano,et al.  Crosslink effect and albumin adsorption onto chitosan/alginate multilayered systems: an in situ QCM-D study. , 2010, Macromolecular bioscience.

[138]  C. Custódio,et al.  Layer-by-layer technique for producing porous nanostructured 3D constructs using moldable freeform assembly of spherical templates. , 2010, Small.

[139]  R. Reis,et al.  Controlling cell behavior through the design of polymer surfaces. , 2010, Small.

[140]  Yong Sik Chung,et al.  The effect of type II collagen coating of chitosan fibrous scaffolds on mesenchymal stem cell adhesion and chondrogenesis. , 2010, Acta biomaterialia.

[141]  Cheng Yan,et al.  Polyurethane (PU) scaffolds prepared by solvent casting/particulate leaching (SCPL) combined with centrifugation , 2010 .

[142]  Rui L Reis,et al.  Potential applications of natural origin polymer-based systems in soft tissue regeneration , 2010, Critical reviews in biotechnology.

[143]  M. Gardel,et al.  Regulation of cell motile behavior by crosstalk between cadherin- and integrin-mediated adhesions , 2010, Proceedings of the National Academy of Sciences.

[144]  Cory Berkland,et al.  Injectable PLGA based colloidal gels for zero-order dexamethasone release in cranial defects. , 2010, Biomaterials.

[145]  C. M. Alves,et al.  Immobilization of fibronectin in chitosan substrates improves cell adhesion and proliferation , 2010, Journal of tissue engineering and regenerative medicine.

[146]  F. Gage,et al.  Metalloproteinase expression is associated with traumatic wound failure. , 2010, The Journal of surgical research.

[147]  James A Bankson,et al.  Three-dimensional tissue culture based on magnetic cell levitation. , 2010, Nature nanotechnology.

[148]  M. Gawaz,et al.  Platelets in regeneration. , 2010, Seminars in thrombosis and hemostasis.

[149]  Milan Mrksich,et al.  Geometric cues for directing the differentiation of mesenchymal stem cells , 2010, Proceedings of the National Academy of Sciences.

[150]  X Wang,et al.  Preparation of aligned porous gelatin scaffolds by unidirectional freeze-drying method. , 2010, Acta biomaterialia.

[151]  L. DiPietro,et al.  Factors Affecting Wound Healing , 2010, Journal of dental research.

[152]  M. C. Stuart,et al.  Emerging applications of stimuli-responsive polymer materials. , 2010, Nature materials.

[153]  Megan S. Lord,et al.  Influence of nanoscale surface topography on protein adsorption and cellular response , 2010 .

[154]  J. Mano,et al.  New Thermo-responsive Hydrogels Based on Poly (N-isopropylacrylamide)/ Hyaluronic Acid Semi-interpenetrated Polymer Networks: Swelling Properties and Drug Release Studies , 2010 .

[155]  Jason A. Burdick,et al.  Controlling Stem Cell Fate with Material Design , 2010, Advanced materials.

[156]  Adam J Engler,et al.  Intrinsic extracellular matrix properties regulate stem cell differentiation. , 2010, Journal of biomechanics.

[157]  Matthias P. Lutolf,et al.  Designing materials to direct stem-cell fate , 2009, Nature.

[158]  J. L. Santos,et al.  Bioinspired superhydrophobic poly(L-lactic acid) surfaces control bone marrow derived cells adhesion and proliferation. , 2009, Journal of biomedical materials research. Part A.

[159]  R L Reis,et al.  Melt-based compression-molded scaffolds from chitosan-polyester blends and composites: Morphology and mechanical properties. , 2009, Journal of biomedical materials research. Part A.

[160]  Rui R. Costa,et al.  Stimuli‐Responsive Thin Coatings Using Elastin‐Like Polymers for Biomedical Applications , 2009 .

[161]  S. Bellis,et al.  Osteogenic differentiation of human mesenchymal stem cells directed by extracellular matrix-mimicking ligands in a biomimetic self-assembled peptide amphiphile nanomatrix. , 2009, Biomacromolecules.

[162]  W. Murphy,et al.  Modular peptide growth factors for substrate-mediated stem cell differentiation. , 2009, Angewandte Chemie.

[163]  F. Guilak,et al.  Control of stem cell fate by physical interactions with the extracellular matrix. , 2009, Cell stem cell.

[164]  J. Coutinho‐Netto,et al.  Cellular aspects of wound healing. , 2009, Anais brasileiros de dermatologia.

[165]  Rui L. Reis,et al.  Perspectives on: Supercritical Fluid Technology for 3D Tissue Engineering Scaffold Applications , 2009 .

[166]  David J. Mooney,et al.  Growth Factors, Matrices, and Forces Combine and Control Stem Cells , 2009, Science.

[167]  D. E. Discher,et al.  Matrix elasticity directs stem cell lineage — Soluble factors that limit osteogenesis , 2009 .

[168]  C. Custódio,et al.  Bioinspired Degradable Substrates with Extreme Wettability Properties , 2009 .

[169]  Jianhong Liao,et al.  Laser micro-processing of cardiovascular stent with fiber laser cutting system , 2009 .

[170]  A. Khademhosseini,et al.  Modular Tissue Engineering: Engineering Biological Tissues from the Bottom Up. , 2009, Soft matter.

[171]  Nicolas H Voelcker,et al.  Stimuli-responsive interfaces and systems for the control of protein-surface and cell-surface interactions. , 2009, Biomaterials.

[172]  G. Schultz,et al.  Interactions between extracellular matrix and growth factors in wound healing , 2009, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[173]  J. Mano,et al.  Bioactive poly(L-lactic acid)-chitosan hybrid scaffolds , 2008 .

[174]  P. Kasten,et al.  Porosity and pore size of beta-tricalcium phosphate scaffold can influence protein production and osteogenic differentiation of human mesenchymal stem cells: an in vitro and in vivo study. , 2008, Acta biomaterialia.

[175]  Erhan Piskin,et al.  Endothelial cell colonization and angiogenic potential of combined nano- and micro-fibrous scaffolds for bone tissue engineering. , 2008, Biomaterials.

[176]  Dong-Yol Yang,et al.  Development of dual scale scaffolds via direct polymer melt deposition and electrospinning for applications in tissue regeneration. , 2008, Acta biomaterialia.

[177]  R. Reis,et al.  Chitosan microparticles as injectable scaffolds for tissue engineering , 2008, Journal of tissue engineering and regenerative medicine.

[178]  A. Khademhosseini,et al.  Directed assembly of cell-laden microgels for fabrication of 3D tissue constructs , 2008, Proceedings of the National Academy of Sciences.

[179]  J. Mano Stimuli‐Responsive Polymeric Systems for Biomedical Applications , 2008 .

[180]  Peter Fratzl,et al.  The effect of geometry on three-dimensional tissue growth , 2008, Journal of The Royal Society Interface.

[181]  J. Mano,et al.  Chitosan coated alginate beads containing poly(N-isopropylacrylamide) for dual-stimuli-responsive drug release. , 2008, Journal of biomedical materials research. Part B, Applied biomaterials.

[182]  H. Tamagawa,et al.  Adhesion force behavior between two gels attached with an electrolytic polymer liquid , 2008 .

[183]  Francesca Ungaro,et al.  Controlled drug delivery in tissue engineering. , 2008, Advanced drug delivery reviews.

[184]  Il Keun Kwon,et al.  Proteomic analysis and quantification of cytokines and chemokines from biomaterial surface-adherent macrophages and foreign body giant cells. , 2007, Journal of biomedical materials research. Part A.

[185]  Masayuki Yamato,et al.  Reconstruction of functional tissues with cell sheet engineering. , 2007, Biomaterials.

[186]  Rui L Reis,et al.  Smart thermoresponsive coatings and surfaces for tissue engineering: switching cell-material boundaries. , 2007, Trends in biotechnology.

[187]  J. Mano,et al.  Thermally Responsive Biomineralization on Biodegradable Substrates , 2007 .

[188]  Bruce Klitzman,et al.  Reduced foreign body response at nitric oxide-releasing subcutaneous implants. , 2007, Biomaterials.

[189]  Giselle Chamberlain,et al.  Concise Review: Mesenchymal Stem Cells: Their Phenotype, Differentiation Capacity, Immunological Features, and Potential for Homing , 2007, Stem cells.

[190]  R. Reis,et al.  Osteochondral defects: present situation and tissue engineering approaches , 2007, Journal of tissue engineering and regenerative medicine.

[191]  Yusuke Arima,et al.  Effect of wettability and surface functional groups on protein adsorption and cell adhesion using well-defined mixed self-assembled monolayers. , 2007, Biomaterials.

[192]  D. Greenhalgh,et al.  Cutaneous Wound Healing , 2007, Journal of burn care & research : official publication of the American Burn Association.

[193]  Antonios G Mikos,et al.  Injectable matrices and scaffolds for drug delivery in tissue engineering. , 2007, Advanced drug delivery reviews.

[194]  K. Ghosh,et al.  Tissue engineering for cutaneous wounds. , 2007, The Journal of investigative dermatology.

[195]  J. Saja,et al.  Preparation and characterization of poly(L-lactic acid)-chitosan hybrid scaffolds with drug release capability. , 2007, Journal of biomedical materials research. Part B, Applied biomaterials.

[196]  N. Kotov,et al.  Successful differentiation of mouse neural stem cells on layer-by-layer assembled single-walled carbon nanotube composite. , 2007, Nano letters.

[197]  K. Ley,et al.  Platelet-neutrophil-interactions: linking hemostasis and inflammation. , 2007, Blood reviews.

[198]  Jin Man Kim,et al.  In vitro and in vivo characteristics of PCL scaffolds with pore size gradient fabricated by a centrifugation method. , 2007, Biomaterials.

[199]  S. Bhatia,et al.  Fabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[200]  Diane J Burgess,et al.  Concurrent delivery of dexamethasone and VEGF for localized inflammation control and angiogenesis. , 2007, Journal of controlled release : official journal of the Controlled Release Society.

[201]  Zhiyong Tang,et al.  Biomedical Applications of Layer‐by‐Layer Assembly: From Biomimetics to Tissue Engineering , 2006 .

[202]  Adam Byron,et al.  Integrin ligands at a glance , 2006, Journal of Cell Science.

[203]  Josep A Planell,et al.  Micro-finite element models of bone tissue-engineering scaffolds. , 2006, Biomaterials.

[204]  S. Sen,et al.  Matrix Elasticity Directs Stem Cell Lineage Specification , 2006, Cell.

[205]  M. Pardue,et al.  The Journal of Cell Biology , 2002 .

[206]  George Broughton,et al.  The Basic Science of Wound Healing , 2006, Plastic and reconstructive surgery.

[207]  Hermann Eichler,et al.  Comparative Analysis of Mesenchymal Stem Cells from Bone Marrow, Umbilical Cord Blood, or Adipose Tissue , 2006, Stem cells.

[208]  Ma Xiaojun,et al.  Optimization of the cell seeding density and modeling of cell growth and metabolism using the modified Gompertz model for microencapsulated animal cell culture , 2006, Biotechnology and bioengineering.

[209]  K. Moore,et al.  Stem Cells and Their Niches , 2006, Science.

[210]  David Farrar,et al.  Surface tailoring for controlled protein adsorption: effect of topography at the nanometer scale and chemistry. , 2006, Journal of the American Chemical Society.

[211]  Alison P McGuigan,et al.  Vascularized Organoid Engineered by Modular Assembly Enables Blood Perfusion , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[212]  A. Salgado,et al.  Nano- and micro-fiber combined scaffolds: A new architecture for bone tissue engineering , 2005, Journal of materials science. Materials in medicine.

[213]  Masayuki Yamato,et al.  Cell sheet engineering: recreating tissues without biodegradable scaffolds. , 2005, Biomaterials.

[214]  T J Sims,et al.  Polymer scaffolds fabricated with pore-size gradients as a model for studying the zonal organization within tissue-engineered cartilage constructs. , 2005, Tissue engineering.

[215]  Jiang Chang,et al.  Preparation, characterization and in vitro release of gentamicin from PHBV/wollastonite composite microspheres. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[216]  João F Mano,et al.  Hydroxypropyl chitosan bearing beta-cyclodextrin cavities: synthesis and slow release of its inclusion complex with a model hydrophobic drug. , 2005, Macromolecular bioscience.

[217]  Linheng Li,et al.  Stem cell niche: structure and function. , 2005, Annual review of cell and developmental biology.

[218]  D. Kaplan,et al.  Porosity of 3D biomaterial scaffolds and osteogenesis. , 2005, Biomaterials.

[219]  E. Entcheva,et al.  Electrospun fine-textured scaffolds for heart tissue constructs. , 2005, Biomaterials.

[220]  S. Ramakrishna,et al.  Characterization of the surface biocompatibility of the electrospun PCL-collagen nanofibers using fibroblasts. , 2005, Biomacromolecules.

[221]  K. Leong,et al.  Significance of synthetic nanostructures in dictating cellular response. , 2005, Nanomedicine : nanotechnology, biology, and medicine.

[222]  J. Hubbell,et al.  Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering , 2005, Nature Biotechnology.

[223]  B. Skikne,et al.  Localization of bone morphogenetic proteins (BMPs)-2, -4, and -6 within megakaryocytes and platelets. , 2004, Bone.

[224]  J. Karp,et al.  Fibrin-filled scaffolds for bone-tissue engineering: An in vivo study. , 2004, Journal of biomedical materials research. Part A.

[225]  A. Weyrich,et al.  Platelets: signaling cells in the immune continuum. , 2004, Trends in immunology.

[226]  Joe Tien,et al.  Mechanotransduction at cell-matrix and cell-cell contacts. , 2004, Annual review of biomedical engineering.

[227]  Dietmar W Hutmacher,et al.  Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems. , 2004, Trends in biotechnology.

[228]  N. Kikuchi,et al.  A novel method for biomaterial scaffold internal architecture design to match bone elastic properties with desired porosity. , 2004, Journal of biomechanics.

[229]  Christopher S. Chen,et al.  Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. , 2004, Developmental cell.

[230]  G. Cagney,et al.  Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. , 2004, Blood.

[231]  Ankush Gosain,et al.  Aging and Wound Healing , 2004, World Journal of Surgery.

[232]  Guoping Chen,et al.  The use of a novel PLGA fiber/collagen composite web as a scaffold for engineering of articular cartilage tissue with adjustable thickness. , 2003, Journal of biomedical materials research. Part A.

[233]  Paquita Nurden,et al.  Autologous platelets as a source of proteins for healing and tissue regeneration , 2003, Thrombosis and Haemostasis.

[234]  Horst Kessler,et al.  RGD modified polymers: biomaterials for stimulated cell adhesion and beyond. , 2003, Biomaterials.

[235]  A. Perets,et al.  Enhancing the vascularization of three-dimensional porous alginate scaffolds by incorporating controlled release basic fibroblast growth factor microspheres. , 2003, Journal of biomedical materials research. Part A.

[236]  T. Kawase,et al.  Platelet-rich plasma-derived fibrin clot formation stimulates collagen synthesis in periodontal ligament and osteoblastic cells in vitro. , 2003, Journal of periodontology.

[237]  V. Sikavitsas,et al.  Effect of fibronectin- and collagen I-coated titanium fiber mesh on proliferation and differentiation of osteogenic cells. , 2003, Tissue engineering.

[238]  J. Vacanti,et al.  A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering. , 2003, Biomaterials.

[239]  R. Landers,et al.  Rapid prototyping of scaffolds derived from thermoreversible hydrogels and tailored for applications in tissue engineering. , 2002, Biomaterials.

[240]  Smadar Cohen,et al.  Optimization of cardiac cell seeding and distribution in 3D porous alginate scaffolds. , 2002, Biotechnology and bioengineering.

[241]  Richard O Hynes,et al.  Integrins Bidirectional, Allosteric Signaling Machines , 2002, Cell.

[242]  G. Hafner,et al.  Growth factor levels in platelet-rich plasma and correlations with donor age, sex, and platelet count. , 2002, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[243]  Larry L Hench,et al.  Third-Generation Biomedical Materials , 2002, Science.

[244]  K. Leong,et al.  The design of scaffolds for use in tissue engineering. Part II. Rapid prototyping techniques. , 2002, Tissue engineering.

[245]  D. Mooney,et al.  Polymeric system for dual growth factor delivery , 2001, Nature Biotechnology.

[246]  W. Kao,et al.  In vivo modulation of host response and macrophage behavior by polymer networks grafted with fibronectin-derived biomimetic oligopeptides: the role of RGD and PHSRN domains. , 2001, Biomaterials.

[247]  L G Griffith,et al.  Effect of pore size and void fraction on cellular adhesion, proliferation, and matrix deposition. , 2001, Tissue engineering.

[248]  G. Lip,et al.  Platelet activation: assessment and quantification. , 2001, European heart journal.

[249]  W. Kao,et al.  Utilizing biomimetic oligopeptides to probe fibronectin-integrin binding and signaling in regulating macrophage function in vitro and in vivo. , 2001, Frontiers in bioscience : a journal and virtual library.

[250]  Mara Riminucci,et al.  Bone Marrow Stromal Stem Cells: Nature, Biology, and Potential Applications , 2001, Stem cells.

[251]  D. Kaufman,et al.  Multilineage Differentiation from Human Embryonic Stem Cell Lines , 2001, Stem cells.

[252]  I Zein,et al.  Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling. , 2001, Journal of biomedical materials research.

[253]  J. Schlessinger Cell Signaling by Receptor Tyrosine Kinases , 2000, Cell.

[254]  M. Reynolds,et al.  Alveolar ridge and sinus augmentation utilizing platelet-rich plasma in combination with freeze-dried bone allograft: case series. , 2000, Journal of periodontology.

[255]  R. Mège,et al.  Immobilized dimers of N-cadherin-Fc chimera mimic cadherin-mediated cell contact formation: contribution of both outside-in and inside-out signals. , 2000, Journal of cell science.

[256]  D. Dormont,et al.  Fibroblast growth factor 2 up regulates telomerase activity in neural precursor cells , 2000, Oncogene.

[257]  A. Singer,et al.  Cutaneous wound healing. , 1999, The New England journal of medicine.

[258]  R. Marx,et al.  Platelet-rich plasma: Growth factor enhancement for bone grafts. , 1998, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[259]  D. Carey,et al.  Syndecans: multifunctional cell-surface co-receptors. , 1997, The Biochemical journal.

[260]  A. Barbul,et al.  General principles of wound healing. , 1997, The Surgical clinics of North America.

[261]  T. T. Dinh,et al.  Myofibroblasts differentiate from fibroblasts when plated at low density. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[262]  B. Gumbiner,et al.  Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis , 1996, Cell.

[263]  D. Brunette,et al.  Substratum surface topography alters cell shape and regulates fibronectin mRNA level, mRNA stability, secretion and assembly in human fibroblasts. , 1995, Journal of cell science.

[264]  M. Pittelkow,et al.  Cell density and culture factors regulate keratinocyte commitment to differentiation and expression of suprabasal K1/K10 keratins. , 1995, The Journal of investigative dermatology.

[265]  Daniel I. C. Wang,et al.  Engineering cell shape and function. , 1994, Science.

[266]  S. Soker,et al.  The binding of vascular endothelial growth factor to its receptors is dependent on cell surface-associated heparin-like molecules. , 1992, The Journal of biological chemistry.

[267]  J. Hubbell,et al.  An RGD spacing of 440 nm is sufficient for integrin alpha V beta 3- mediated fibroblast spreading and 140 nm for focal contact and stress fiber formation , 1991, The Journal of cell biology.

[268]  M. Takeichi,et al.  Cadherin cell adhesion receptors as a morphogenetic regulator. , 1991, Science.

[269]  J. Hubbell,et al.  Covalent surface immobilization of Arg-Gly-Asp- and Tyr-Ile-Gly-Ser-Arg-containing peptides to obtain well-defined cell-adhesive substrates. , 1990, Analytical biochemistry.

[270]  Joseph Schlessinger,et al.  Signal transduction by receptors with tyrosine kinase activity , 1990, Cell.

[271]  M. Sporn,et al.  Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes. , 1986, Journal of immunology.

[272]  Luca Wurfel,et al.  Principles Of Tissue Engineering , 2016 .

[273]  Rui R. Costa,et al.  Compartmentalized bioencapsulated liquefied 3D macro-construct by perfusion-based layer-by-layer technique , 2015 .

[274]  Xiaojun Yu,et al.  8 – Tendon tissue engineering , 2015 .

[275]  Y. Tabata,et al.  Enhancement of bone regeneration by dual release of a macrophage recruitment agent and platelet-rich plasma from gelatin hydrogels. , 2014, Biomaterials.

[276]  M. Ruel,et al.  Cardiac Tissue Engineering , 2014, Methods in Molecular Biology.

[277]  Tabatabaei Qomi,et al.  The Design of Scaffolds for Use in Tissue Engineering , 2014 .

[278]  Philip Kollmannsberger,et al.  Geometry as a Factor for Tissue Growth: Towards Shape Optimization of Tissue Engineering Scaffolds , 2013, Advanced healthcare materials.

[279]  Shuji Hashimoto,et al.  A self-assembling method for polymer gel components , 2013, 2013 IEEE International Conference on Robotics and Biomimetics (ROBIO).

[280]  Michiya Matsusaki,et al.  Survival and structural evaluations of three-dimensional tissues fabricated by the hierarchical cell manipulation technique. , 2013, Acta biomaterialia.

[281]  Daniel J. Gould,et al.  Covalently immobilized platelet-derived growth factor-BB promotes angiogenesis in biomimetic poly(ethylene glycol) hydrogels. , 2011, Acta biomaterialia.

[282]  Robert A. Campbell,et al.  Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum , 2011, Seminars in Immunopathology.

[283]  Hugo Leite-Almeida,et al.  Development and characterization of a novel hybrid tissue engineering-based scaffold for spinal cord injury repair. , 2010, Tissue engineering. Part A.

[284]  Robert Langer,et al.  High throughput methods applied in biomaterial development and discovery. , 2010, Biomaterials.

[285]  R. Reis,et al.  Preparation of chitosan scaffolds loaded with dexamethasone for tissue engineering applications using supercritical fluid technology , 2009 .

[286]  R. Franke,et al.  Stimulation of monocytes and macrophages: possible influence of surface roughness. , 2008, Clinical hemorheology and microcirculation.

[287]  A. Wagers,et al.  No place like home: anatomy and function of the stem cell niche , 2008, Nature Reviews Molecular Cell Biology.

[288]  D Lacroix,et al.  A finite element study of mechanical stimuli in scaffolds for bone tissue engineering. , 2008, Journal of biomechanics.

[289]  Robert A. Brown,et al.  Effect of cell density on osteoblastic differentiation and matrix degradation of biomimetic dense collagen scaffolds. , 2008, Biomacromolecules.

[290]  Rui L. Reis,et al.  Carboxymethyl chitosan-graft-phosphatidylethanolamine: Amphiphilic matrices for controlled drug delivery , 2007 .

[291]  Tarynn M Witten,et al.  Impaired wound healing. , 2007, Clinics in dermatology.

[292]  Juin-Yih Lai,et al.  Preparation of porous scaffolds by using freeze-extraction and freeze-gelation methods. , 2004, Biomaterials.

[293]  Yasuhiko Tabata,et al.  Tissue regeneration based on growth factor release. , 2003, Tissue engineering.

[294]  Y. Kuboki,et al.  Osteoblast-related gene expression of bone marrow cells during the osteoblastic differentiation induced by type I collagen. , 2001, Journal of biochemistry.

[295]  E. Lüllau,et al.  Animal Cell Technology: From Target to Market , 2001, ESACT Proceedings.

[296]  Robert B. Thompson,et al.  The ₂-localization of () , 1998 .

[297]  J. Vacanti,et al.  Tissue engineering : Frontiers in biotechnology , 1993 .

[298]  J. Spring,et al.  Biology of the syndecans: a family of transmembrane heparan sulfate proteoglycans. , 1992, Annual review of cell biology.

[299]  R. Schofield The relationship between the spleen colony-forming cell and the haemopoietic stem cell. , 1978, Blood cells.