Therapy and clinical trials in frontotemporal dementia: past, present, and future
暂无分享,去创建一个
[1] H. Arai,et al. 18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease , 2016, The Journal of Nuclear Medicine.
[2] Jorge Sepulcre,et al. Tau positron emission tomographic imaging in aging and early Alzheimer disease , 2016, Annals of neurology.
[3] D. J. Brooks,et al. Tau imaging in neurodegenerative diseases , 2015, European Journal of Nuclear Medicine and Molecular Imaging.
[4] Keith A. Johnson,et al. Validating novel tau positron emission tomography tracer [F‐18]‐AV‐1451 (T807) on postmortem brain tissue , 2015, Annals of neurology.
[5] E. Gómez-Tortosa,et al. Behavioral Evolution of Progressive Semantic Aphasia in Comparison with Nonfluent Aphasia , 2015, Dementia and Geriatric Cognitive Disorders.
[6] Cassandra J. Anor,et al. Mutation analysis of C9orf72 in patients with corticobasal syndrome , 2015, Neurobiology of Aging.
[7] L. Petrucelli,et al. Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers , 2015, Acta Neuropathologica.
[8] P. Wong,et al. Susceptibility-weighted MRI in mild traumatic brain injury , 2015, Neurology.
[9] N. Krogan,et al. Critical Role of Acetylation in Tau-Mediated Neurodegeneration and Cognitive Deficits , 2015, Nature Medicine.
[10] Donna C. Tippett,et al. Treatment of Primary Progressive Aphasia , 2015, Current Treatment Options in Neurology.
[11] N. Pearce,et al. Neurofilament light chain , 2015, Neurology.
[12] D. Neary,et al. Cognitive–behavioural features of progressive supranuclear palsy syndrome overlap with frontotemporal dementia , 2015, Journal of Neurology.
[13] Keith A. Johnson,et al. Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging , 2015, Neuropathology and applied neurobiology.
[14] M. Borrie,et al. Oxytocin for frontotemporal dementia , 2015, Neurology.
[15] J. Trojanowski,et al. Microtubule-stabilizing agents as potential therapeutics for neurodegenerative disease. , 2014, Bioorganic & medicinal chemistry.
[16] L. Collin,et al. Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease. , 2014, Brain : a journal of neurology.
[17] Bruce H. Morimoto,et al. Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial , 2014, The Lancet Neurology.
[18] M. Diamond,et al. Prion-like Properties of Tau Protein: The Importance of Extracellular Tau as a Therapeutic Target* , 2014, The Journal of Biological Chemistry.
[19] H. Huppertz,et al. Tideglusib reduces progression of brain atrophy in progressive supranuclear palsy in a randomized trial , 2014, Movement disorders : official journal of the Movement Disorder Society.
[20] E. Tolosa,et al. A phase 2 trial of the GSK‐3 inhibitor tideglusib in progressive supranuclear palsy , 2014, Movement disorders : official journal of the Movement Disorder Society.
[21] U. Sengupta,et al. Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles , 2014, The Journal of Neuroscience.
[22] M. Muiesan,et al. Results from a pilot study on amiodarone administration in monogenic frontotemporal dementia with granulin mutation , 2014, Neurological Sciences.
[23] Chadwick M. Hales,et al. Reduced CSF p-Tau181 to Tau ratio is a biomarker for FTLD-TDP , 2013, Neurology.
[24] B. Franke,et al. Dissociable Effects of Dopamine and Serotonin on Reversal Learning , 2013, Neuron.
[25] Nipun A. Mistry,et al. RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention , 2013, Neuron.
[26] Gene W. Yeo,et al. Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration , 2013, Proceedings of the National Academy of Sciences.
[27] L. Petrucelli,et al. Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion , 2013, Science Translational Medicine.
[28] F. van Leuven,et al. Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy , 2013, PloS one.
[29] Bruno Vellas,et al. Designing drug trials for Alzheimer’s disease: What we have learned from the release of the phase III antibody trials: A report from the EU/US/CTAD Task Force , 2013, Alzheimer's & Dementia.
[30] D. Arciniegas,et al. Donepezil-induced confusional state in a patient with autopsy-proven behavioral-variant frontotemporal dementia. , 2013, The Journal of neuropsychiatry and clinical neurosciences.
[31] B. Ghetti,et al. Brain homogenates from human tauopathies induce tau inclusions in mouse brain , 2013, Proceedings of the National Academy of Sciences.
[32] A. Pestronk,et al. An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study , 2013, The Lancet Neurology.
[33] P. Davies,et al. Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificity , 2013, PloS one.
[34] Takemi Kimura,et al. Pilot study of pharmacological treatment for frontotemporal dementia: Risk of donepezil treatment for behavioral and psychological symptoms , 2013, Geriatrics & gerontology international.
[35] K. Kortte,et al. Behavioural interventions for enhancing life participation in behavioural variant frontotemporal dementia and primary progressive aphasia , 2013, International review of psychiatry.
[36] D. Geschwind,et al. TDP-43 frontotemporal lobar degeneration and autoimmune disease , 2013, Journal of Neurology, Neurosurgery & Psychiatry.
[37] N. Tsuno,et al. Managing abnormal eating behaviours in frontotemporal lobar degeneration patients with topiramate , 2013, Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society.
[38] Robert V Farese,et al. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: The next therapeutic frontier) , 2013, Alzheimer's & Dementia.
[39] Kevin F. Bieniek,et al. Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS , 2013, Neuron.
[40] Murray Grossman,et al. Memantine in patients with frontotemporal lobar degeneration: a multicentre, randomised, double-blind, placebo-controlled trial , 2013, The Lancet Neurology.
[41] Mark Hallett,et al. Criteria for the diagnosis of corticobasal degeneration , 2013, Neurology.
[42] R. Reeves,et al. Aripiprazole for sexually inappropriate vocalizations in frontotemporal dementia. , 2012, Journal of clinical psychopharmacology.
[43] A. Boxer,et al. Treatment implications of C9ORF72 , 2012, Alzheimer's Research & Therapy.
[44] N. Herrmann,et al. Serotonergic function and treatment of behavioral and psychological symptoms of frontotemporal dementia. , 2012, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.
[45] T. Cooper,et al. RNA-binding proteins in microsatellite expansion disorders: Mediators of RNA toxicity , 2012, Brain Research.
[46] C. Jack,et al. Rates of brain atrophy and clinical decline over 6 and 12-month intervals in PSP: determining sample size for treatment trials. , 2012, Parkinsonism & related disorders.
[47] D. Neary,et al. Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations. , 2012, Brain : a journal of neurology.
[48] J. Stewart,et al. Treatment of indiscriminate, inappropriate sexual behavior in frontotemporal dementia with carbamazepine. , 2012, Journal of clinical psychopharmacology.
[49] David Heckerman,et al. A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD , 2011, Neuron.
[50] D. Geschwind,et al. Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS , 2011, Neuron.
[51] Nick C Fox,et al. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. , 2011, Brain : a journal of neurology.
[52] P. Davies,et al. Passive Immunization with Anti-Tau Antibodies in Two Transgenic Models , 2011, The Journal of Biological Chemistry.
[53] J. Trojanowski,et al. Clinicopathological correlations in corticobasal degeneration , 2011, Annals of neurology.
[54] E. Sigurdsson,et al. Passive immunization targeting pathological phospho‐tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain , 2011, Journal of neurochemistry.
[55] Zhinan Yin,et al. The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice , 2011, Science.
[56] P. Nestor. Reversal of abnormal eating and drinking behaviour in a frontotemporal lobar degeneration patient using low-dose topiramate , 2011, Journal of Neurology, Neurosurgery & Psychiatry.
[57] Robert V Farese,et al. Suberoylanilide Hydroxamic Acid (Vorinostat) Up-regulates Progranulin Transcription , 2011, The Journal of Biological Chemistry.
[58] B. Miller,et al. Classification of primary progressive aphasia and its variants , 2011, Neurology.
[59] K. Sleegers,et al. Rescue of Progranulin Deficiency Associated with Frontotemporal Lobar Degeneration by Alkalizing Reagents and Inhibition of Vacuolar ATPase , 2011, The Journal of Neuroscience.
[60] E. Yaksi,et al. Electrical Coupling between Olfactory Glomeruli , 2010, Neuron.
[61] A. Lees,et al. Does corticobasal degeneration exist? A clinicopathological re-evaluation. , 2010, Brain : a journal of neurology.
[62] B. Boeve,et al. Clinical, neuroimaging and neuropathological features of a new chromosome 9p-linked FTD-ALS family , 2010, Journal of Neurology, Neurosurgery & Psychiatry.
[63] D. Berg,et al. Rivastigmine for the treatment of dementia in patients with progressive supranuclear palsy: Clinical observations as a basis for power calculations and safety analysis , 2010, Alzheimer's & Dementia.
[64] E. Ross,et al. Behavioural abnormalities associated with rapid deterioration of language functions in semantic dementia respond to sertraline , 2009, Journal of Neurology, Neurosurgery & Psychiatry.
[65] J. Neuhaus,et al. An Open-label Study of Memantine Treatment in 3 Subtypes of Frontotemporal Lobar Degeneration , 2009, Alzheimer disease and associated disorders.
[66] K. Sleegers,et al. Serum biomarker for progranulin‐associated frontotemporal lobar degeneration , 2009, Annals of neurology.
[67] R. Petersen,et al. Plasma progranulin levels predict progranulin mutation status in frontotemporal dementia patients and asymptomatic family members , 2009, Brain : a journal of neurology.
[68] J. Grafman,et al. Stimulant treatment of frontotemporal dementia in 8 patients. , 2008, The Journal of clinical psychiatry.
[69] Nathaniel Mercaldo,et al. Development of methodology for conducting clinical trials in frontotemporal lobar degeneration. , 2008, Brain : a journal of neurology.
[70] G. Binetti,et al. Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration , 2008, Neurology.
[71] Peter Heutink,et al. Mutations in progranulin (GRN) within the spectrum of clinical and pathological phenotypes of frontotemporal dementia , 2008, The Lancet Neurology.
[72] Leonardo Franklin Fontenelle,et al. Topiramate may modulate alcohol abuse but not other compulsive behaviors in frontotemporal dementia: case report. , 2008, Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology.
[73] A. Kertesz,et al. Galantamine in Frontotemporal Dementia and Primary Progressive Aphasia , 2008, Dementia and Geriatric Cognitive Disorders.
[74] J. Merrilees. A Model for Management of Behavioral Symptoms in Frontotemporal Lobar Degeneration , 2007, Alzheimer disease and associated disorders.
[75] Ayodeji A. Asuni,et al. Immunotherapy Targeting Pathological Tau Conformers in a Tangle Mouse Model Reduces Brain Pathology with Associated Functional Improvements , 2007, The Journal of Neuroscience.
[76] L. Golbe,et al. A clinical rating scale for progressive supranuclear palsy. , 2007, Brain : a journal of neurology.
[77] J. Trojanowski,et al. Cognitive and motor assessment in autopsy-proven corticobasal degeneration , 2007, Neurology.
[78] M. Swanberg. Memantine for Behavioral Disturbances in Frontotemporal Dementia: A Case Series , 2007, Alzheimer disease and associated disorders.
[79] Matthias J. Müller,et al. Clinical improvement in a case of frontotemporal dementia under aripiprazole treatment corresponds to partial recovery of disturbed frontal glucose metabolism , 2007, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.
[80] S H Appel,et al. Prevalence and patterns of cognitive impairment in sporadic ALS , 2005, Neurology.
[81] J. Shapira,et al. Stereotypical movements and frontotemporal dementia , 2005, Movement disorders : official journal of the Movement Disorder Society.
[82] B. L. Miller,et al. The natural history of temporal variant frontotemporal dementia , 2005, Neurology.
[83] Daniela Perani,et al. Glucose metabolism and serotonin receptors in the frontotemporal lobe degeneration , 2005, Annals of neurology.
[84] K. Blennow,et al. Increased intrathecal inflammatory activity in frontotemporal dementia: pathophysiological implications , 2004, Journal of Neurology, Neurosurgery & Psychiatry.
[85] F. Pasquier,et al. Frontotemporal Dementia: A Randomised, Controlled Trial with Trazodone , 2004, Dementia and Geriatric Cognitive Disorders.
[86] B. Sahakian,et al. Paroxetine does not improve symptoms and impairs cognition in frontotemporal dementia: a double-blind randomized controlled trial , 2004, Psychopharmacology.
[87] Pierre N Tariot,et al. Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial. , 2004, JAMA.
[88] A. Bava,et al. Olanzapine as a treatment of neuropsychiatric disorders of Alzheimer's disease and other dementias: A 24-month follow-up of 68 patients , 2003, American journal of Alzheimer's disease and other dementias.
[89] Nick C Fox,et al. Vulnerability to neuroleptic side effects in frontotemporal lobar degeneration , 2003, International journal of geriatric psychiatry.
[90] A. Bava,et al. Frontotemporal Dementia: Paroxetine as a Possible Treatment of Behavior Symptoms , 2002, European Neurology.
[91] C. Robinson,et al. Progressive supranuclear palsy diagnosis and confounding features: Report on 16 autopsied cases , 2002, Movement disorders : official journal of the Movement Disorder Society.
[92] M. Mendez,et al. Goals in symptomatic pharmacologic management of frontotemporal lobar degeneration , 2002, American journal of Alzheimer's disease and other dementias.
[93] J. Trojanowski,et al. Sporadic Pick's disease: A tauopathy characterized by a spectrum of pathological τ isoforms in gray and white matter , 2002, Annals of neurology.
[94] D. Dickson,et al. Morphological and Biochemical Correlations of Abnormal Tau Filaments in Progressive Supranuclear Palsy , 2002, Journal of neuropathology and experimental neurology.
[95] M. Hallett,et al. Randomized placebo-controlled trial of donepezil in patients with progressive supranuclear palsy , 2001, Neurology.
[96] H. P. Schmitt,et al. Frontotemporal dementia: evidence for impairment of ascending serotoninergic but not noradrenergic innervation , 2001, Acta Neuropathologica.
[97] C. Colosimo,et al. Donepezil in the treatment of progressive supranuclear palsy , 2001, Acta neurologica Scandinavica.
[98] R. Curtis,et al. Case of pick's central lobar atrophy with apparent stabilization of cognitive decline after treatment with risperidone. , 2000, Journal of clinical psychopharmacology.
[99] A. Delacourte,et al. Comparative Biochemistry of Tau in Progressive Supranuclear Palsy, Corticobasal Degeneration, FTDP‐17 and Pick's Disease , 1999, Brain pathology.
[100] P. Francis,et al. Neurochemical Features of Frontotemporal Dementia , 1999, Dementia and Geriatric Cognitive Disorders.
[101] J. Hodges,et al. Frontotemporal dementia , 1999, Neurology.
[102] K. Jellinger,et al. Pharmacological therapy in progressive supranuclear palsy. , 1998, Archives of neurology.
[103] R. Vejsada,et al. Persephin, a Novel Neurotrophic Factor Related to GDNF and Neurturin , 1998, Neuron.
[104] J. Swartz,et al. Frontotemporal dementia: treatment response to serotonin selective reuptake inhibitors. , 1997, The Journal of clinical psychiatry.
[105] M. Roth,et al. Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[106] M. Hallett,et al. Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome) , 1996, Neurology.
[107] C. Jahr,et al. β-Adrenergic Regulation of Synaptic NMDA Receptors by cAMP-Dependent Protein Kinase , 1996, Neuron.
[108] D. Dickson,et al. Neuropathologic Overlap of Progressive Supranuclear Palsy, Pick's Disease and Corticobasal Degeneration , 1996, Journal of neuropathology and experimental neurology.
[109] K. Kosik,et al. Structure and novel exons of the human tau gene. , 1992, Biochemistry.
[110] A. Hyman,et al. Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau. , 1992, Molecular biology of the cell.
[111] M. Calvani,et al. Clues to the Mechanism of Action of Acetyl-L-Carnitine in the Central Nervous System , 1991 .
[112] T. Yokota,et al. Serum antibodies to HTLV‐I in autonomic failure with multiple system atrophy , 1990, Annals of neurology.
[113] F. Clementi,et al. Cellular immune response against acetylcholine receptor in myasthenia gravis , 1979, Neurology.
[114] G. Edsall. PASSIVE IMMUNIZATION. , 1963, Pediatrics.
[115] R. Staff,et al. Tau aggregation inhibitor therapy: an exploratory phase 2 study in mild or moderate Alzheimer's disease. , 2015, Journal of Alzheimer's disease : JAD.
[116] J. Kramer,et al. Cerebrospinal fluid neurofilament concentration reflects disease severity in frontotemporal degeneration. , 2014, Annals of neurology.
[117] U. Sengupta,et al. Specific targeting of tau oligomers in Htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds. , 2014, Journal of Alzheimer's disease : JAD.
[118] M. Walterfang,et al. Topiramate for Abnormal Eating Behaviour in Frontotemporal Dementia , 2013, Behavioural neurology.
[119] C. Volteau,et al. Memantine in behavioral variant frontotemporal dementia: negative results. , 2011, Journal of Alzheimer's disease : JAD.
[120] R. Panush. The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice , 2011 .
[121] M. Freedman,et al. Frontotemporal dementia and pharmacologic interventions. , 2010, The Journal of neuropsychiatry and clinical neurosciences.
[122] M. Mendez,et al. Preliminary findings: behavioral worsening on donepezil in patients with frontotemporal dementia. , 2007, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.
[123] M. Riepe,et al. Memantine in Moderate-to-severe Alzheimer's Disease , 2006 .
[124] A. Bava,et al. Rivastigmine in Frontotemporal Dementia , 2004, Drugs & aging.
[125] J. Trojanowski,et al. Tau and axonopathy in neurodegenerative disorders , 2002, NeuroMolecular Medicine.
[126] S. Ringel,et al. Observations on the efficacy of L-dopa in progressive supranuclear palsy. , 1971, European neurology.