Evaluation of the defined daily dose method for estimating anti-infective use in a university hospital.

Antiinfective resistance resulting from selection pressure is a generally well-accepted occurrence.[1][1]–[5][2] Many hospitals attempt to limit antiinfective use and misuse by implementing active and passive control measures.[6][3] A variety of methods for tracking antiinfective use patterns are

[1]  P. Gastmeier,et al.  Design of a Surveillance System of Antibiotic Use and Bacterial Resistance in German Intensive Care Units (SARI) , 2003, Infection.

[2]  L. Leibovici,et al.  Departmental consumption of antibiotic drugs and subsequent resistance: a quantitative link. , 2001, The Journal of antimicrobial chemotherapy.

[3]  R. Weinstein,et al.  Multi-hospital analysis of antimicrobial usage and resistance trends. , 1997, Diagnostic microbiology and infectious disease.

[4]  D. Gerding,et al.  Society for Healthcare Epidemiology of America and Infectious Diseases Society of America Joint Committee on the Prevention of Antimicrobial Resistance: guidelines for the prevention of antimicrobial resistance in hospitals. , 1997, Infection control and hospital epidemiology.

[5]  L. Briceland,et al.  Survey of Antibiotic Control Policies in University-Affiliated Teaching Institutions , 1996, The Annals of pharmacotherapy.

[6]  S. Levy.  Balancing the drug-resistance equation. , 1994, Trends in microbiology.

[7]  A. Wessling,et al.  Measurement of drug use in a defined population , 1990, European Journal of Clinical Pharmacology.

[8]  C. Fletcher,et al.  Patterns of Antibiotic Use and Expenditures During 7 Years at a University Hospital , 1990, Pharmacotherapy.

[9]  N. F. Col,et al.  Estimating worldwide current antibiotic usage: report of Task Force 1. , 1987, Reviews of infectious diseases.

[10]  J. Mcgowan,et al.  Antimicrobial resistance in hospital organisms and its relation to antibiotic use. , 1983, Reviews of infectious diseases.

[11]  R. Herings,et al.  Application of the ATC/DDD methodology to monitor antibiotic drug use , 2005, European Journal of Clinical Microbiology and Infectious Diseases.

[12]  H. Sørensen,et al.  Risk of resistance related to antibiotic use before admission in patients with community-acquired bacteraemia. , 1999, The Journal of antimicrobial chemotherapy.