Minicircle DNA is superior to plasmid DNA in eliciting antigen-specific CD8+ T-cell responses.
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P. Hwu | Zhi-Ying Chen | A. Salazar | B. Blazar | Mark J. Osborn | J. Ohlfest | A. Litterman | Bruce R Blazar | Patrick Hwu | John R Ohlfest | Andres M Salazar | Zhi-Ying Chen | Sara E Hamilton | Mark J Osborn | C. Pennell | Wynette M Dietz | Nicole E B Skinner | Michelle D Jund | Suzanne M Heitfeld | Adam J Litterman | Christopher A Pennell | Nicole Skinner | S. Hamilton | Wynette M. Dietz | Michelle D. Jund | Sara E. Hamilton
[1] Siqun Xu,et al. © The American Society of Gene & Cell Therapy original article The Extragenic Spacer Length Between the 5 ′ and 3 ′ Ends of the Transgene Expression Cassette Affects Transgene Silencing From Plasmid-based Vectors , 2012 .
[2] R. Steinman,et al. Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans , 2011, The Journal of experimental medicine.
[3] D. Weiner,et al. Clinical applications of DNA vaccines: current progress. , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[4] G. Freeman,et al. © The American Society of Gene & Cell Therapy original article Minicircle DNA-based Gene Therapy Coupled With Immune Modulation Permits Long-term Expression of α-l-Iduronidase in Mice With , 2022 .
[5] M. Kay,et al. A Simple And Rapid Minicircle DNA Vector Manufacturing System , 2010, Nature Biotechnology.
[6] L. Joosten,et al. A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: upregulation of dectin-1 in psoriasis. , 2010, The Journal of investigative dermatology.
[7] A. Hovav,et al. Directly Transfected Langerin+ Dermal Dendritic Cells Potentiate CD8+ T Cell Responses following Intradermal Plasmid DNA Immunization , 2010, The Journal of Immunology.
[8] A. Jestin,et al. Biosafety of DNA vaccines: New generation of DNA vectors and current knowledge on the fate of plasmids after injection. , 2010, Vaccine.
[9] J. Gehl,et al. Duration and level of transgene expression after gene electrotransfer to skin in mice , 2010, Gene Therapy.
[10] N. Romani,et al. Langerhans cells and more: langerin‐expressing dendritic cell subsets in the skin , 2010, Immunological reviews.
[11] Marco Marra,et al. SKPs derive from hair follicle precursors and exhibit properties of adult dermal stem cells. , 2009, Cell stem cell.
[12] Frank O. Nestle,et al. Skin immune sentinels in health and disease , 2009, Nature Reviews Immunology.
[13] D. G. Gibson,et al. Enzymatic assembly of DNA molecules up to several hundred kilobases , 2009, Nature Methods.
[14] A. Lew,et al. Equivalent stimulation of naive and memory CD8 T cells by DNA vaccination: a dendritic cell‐dependent process , 2009, Immunology and cell biology.
[15] M. Kay,et al. Gene Transfer to Mouse Heart and Skeletal Muscles Using a Minicircle Expressing Human Vascular Endothelial Growth Factor , 2009, Journal of cardiovascular pharmacology.
[16] D. Weiner,et al. DNA vaccines: developing new strategies to enhance immune responses , 2008, Immunologic research.
[17] T. Schumacher,et al. Optimization of intradermal vaccination by DNA tattooing in human skin. , 2008, Human gene therapy.
[18] P. Hwu,et al. Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer , 2008, Proceedings of the National Academy of Sciences.
[19] M. Kay,et al. Radioprotection in vitro and in vivo by minicircle plasmid carrying the human manganese superoxide dismutase transgene. , 2008, Human gene therapy.
[20] L. Lefrançois,et al. Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection. , 2008, Immunity.
[21] M. Kay,et al. Silencing of episomal transgene expression in liver by plasmid bacterial backbone DNA is independent of CpG methylation. , 2008, Molecular therapy : the journal of the American Society of Gene Therapy.
[22] N. Letvin,et al. Duration of Antigen Expression In Vivo following DNA Immunization Modifies the Magnitude, Contraction, and Secondary Responses of CD8+ T Lymphocytes1 , 2007, The Journal of Immunology.
[23] T. Schumacher,et al. In Vivo Antigen Stability Affects DNA Vaccine Immunogenicity , 2007, The Journal of Immunology.
[24] M. Kay,et al. Histone Modifications Are Associated with the Persistence or Silencing of Vector-mediated Transgene Expression in Vivo , 2022 .
[25] Chien-Fu Hung,et al. A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression , 2005, Nature Medicine.
[26] M. Kay,et al. Increased maintenance and persistence of transgenes by excision of expression cassettes from plasmid sequences in vivo. , 2005, Human gene therapy.
[27] A. Mirmohammadsadegh,et al. Topical application of plasmid DNA to mouse and human skin , 2005, Journal of Molecular Medicine.
[28] M. Kay,et al. Improved production and purification of minicircle DNA vector free of plasmid bacterial sequences and capable of persistent transgene expression in vivo. , 2005, Human gene therapy.
[29] Y. Oh,et al. Skin permeation, biodistribution, and expression of topically applied plasmid DNA , 2004, The journal of gene medicine.
[30] J. Nalbantoglu,et al. Factors influencing the efficacy, longevity, and safety of electroporation-assisted plasmid-based gene transfer into mouse muscles. , 2004, Molecular therapy : the journal of the American Society of Gene Therapy.
[31] B. D. de Lumen,et al. Dynamics of keratinocytes in vivo using HO labeling: a sensitive marker of epidermal proliferation state. , 2004, The Journal of investigative dermatology.
[32] M. Kay,et al. Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo , 2004, Gene Therapy.
[33] M. Kay,et al. Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo. , 2003, Molecular therapy : the journal of the American Society of Gene Therapy.
[34] R. Dudani,et al. Multiple Mechanisms Compensate to Enhance Tumor-Protective CD8+ T Cell Response in the Long-Term Despite Poor CD8+ T Cell Priming Initially: Comparison Between an Acute Versus a Chronic Intracellular Bacterium Expressing a Model Antigen1 , 2002, The Journal of Immunology.
[35] N. Perrimon,et al. I-SceI endonuclease, a new tool for studying DNA double-strand break repair mechanisms in Drosophila. , 1999, Genetics.
[36] D. Scherman,et al. Minicircle: an improved DNA molecule for in vitro and in vivo gene transfer , 1999, Gene Therapy.
[37] D. Scherman,et al. A new DNA vehicle for nonviral gene delivery: supercoiled minicircle , 1997, Gene Therapy.
[38] J. Yewdell,et al. Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody. , 1997, Immunity.
[39] S. Johnston,et al. Biological features of genetic immunization. , 1997, Vaccine.
[40] Philip J. R. Goulder,et al. Phenotypic Analysis of Antigen-Specific T Lymphocytes , 1996, Science.
[41] E. Wagner,et al. The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice. , 1996, Nucleic acids research.
[42] R. Zinkernagel,et al. CD8+ T cell‐mediated protection against an intracellular bacterium by perforin‐dependent cytotoxicity , 1994, European journal of immunology.
[43] D. Loh,et al. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. , 1994, Immunity.
[44] D. Dwyer,et al. Listeriosis — a review of eighty‐four cases , 1994, The Medical journal of Australia.
[45] Kristin A. Hogquist,et al. T cell receptor antagonist peptides induce positive selection , 1994, Cell.
[46] E. Schlick,et al. Pharmacokinetic and therapeutic activity of polyinosinic-polycytidylic acid stabilized with poly-L-lysine in carboxymethylcellulose [poly(I,C)-LC]. , 1985, Journal of biological response modifiers.
[47] A. Fire,et al. © The American Society of Gene & Cell Therapy original article Minicircle DNA Vectors Achieve Sustained Expression Reflected by Active Chromatin and Transcriptional , 2022 .
[48] E. Ingulli. Tracing tolerance and immunity in vivo by CFSE-labeling of administered cells. , 2007, Methods in molecular biology.